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pro vyhledávání: '"Antonin Kroehn"'
Autor:
David R. Vesey, Christopher H. Hill, Rino A. Bit, Christopher J. Hobbs, Eric A. Kitas, Brad S. Sherborne, David Pole, Fiona Wilson, Antonin Kroehn, Glyn Williams, Bill Harris, Ian R. Kilford, David Banner, Neera Borkakoti, D.Lee Walmsley, David Whittaker, Paul Rugman, Andrew Cansfield, Ian Edward David Smith, Allan Surgenor, Katherine L. Hilyard, Peter Lovell
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(10)
Starting from the tetrapeptide Ac-pYEEI-NHMe and using a structure-based approach, we have designed and synthesised a peptidomimetic ligand for p56(lck) SH2 domain containing a conformationally restricted replacement for the two glutamate residues. W