N -(2-Oxo-3-oxetanyl)carbamic acid esters as N-acylethanolamine acid amidase inhibitors: Synthesis and structure-activity and structure-property relationships

Autor: Duranti, A, Tontini, A, Antonietti, F, Vacondio, F, Fioni, A, Silva, C, Lodola, A, Rivara, S, Solorzano, C, Piomelli, D, Tarzia, G, Mor, M

Publikováno v: Duranti, A; Tontini, A; Antonietti, F; Vacondio, F; Fioni, A; Silva, C; et al.(2012). N-(2-Oxo-3-oxetanyl)carbamic acid esters as N-acylethanolamine acid amidase inhibitors: Synthesis and structure-activity and structure-property relationships. Journal of Medicinal Chemistry, 55(10), 4824-4836. doi: 10.1021/jm300349j. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8282x958

The β-lactone ring of N-(2-oxo-3-oxetanyl)amides, a class of N-acylethanolamine acid amidase (NAAA) inhibitors endowed with anti-inflammatory properties, is responsible for both NAAA inhibition and low compound stability. Here, we investigate the st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::c27c2edac9dd3454ddb1c47f83632ce5
http://www.escholarship.org/uc/item/8282x958

Synthesis and structure - Activity relationships of N -(2-Oxo-3-oxetanyl) amides as N -acylethanolamine-hydrolyzing acid amidase inhibitors

Autor: Solorzano, C, Antonietti, F, Duranti, A, Tontini, A, Rivara, S, Lodola, A, Vacondio, F, Tarzia, G, Piomelli, D, Mor, M

Publikováno v: Solorzano, C; Antonietti, F; Duranti, A; Tontini, A; Rivara, S; Lodola, A; et al.(2010). Synthesis and structure-Activity relationships of N-(2-Oxo-3-oxetanyl) amides as N-acylethanolamine-hydrolyzing acid amidase inhibitors. Journal of Medicinal Chemistry, 53(15), 5770-5781. doi: 10.1021/jm100582w. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4m75c2bw

The fatty acid ethanolamides (FAEs) are a family of bioactive lipid mediators that include the endogenous agonist of peroxisome proliferator- activated receptor-α, palmitoylethanolamide (PEA). FAEs are hydrolyzed intracellularly by either fatty acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::ce621f210659a159bbe83aaafd22560c
http://www.escholarship.org/uc/item/4m75c2bw

suicidio da inalazione di emissioni gassose prodotte da autoveicoli dotati di convertitori catalitici

Autor: Antonietti, F., Brunaldi, Vincenzo, Mortoni, L., Avato, Francesco Maria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3709::6a1adfbbabafd6251d6afe68f0e341fd
http://hdl.handle.net/11392/1396356

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Changes in the physical and chemical properties of floodwater and sediment in an experimental ricefield (Reggio Emilia, Italy)

Autor: Antonietti, R., Viaroli, P., Antonietti, F.

Publikováno v: Hydrobiologia; January 1987, Vol. 144 Issue: 1 p83-88, 6p