Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Antonietta Fazio"'
Autor:
Antonietta Fazio, Alberto Di Martino, Matteo Brunello, Francesco Traina, Maria Vittoria Marvi, Antonio Mazzotti, Cesare Faldini, Lucia Manzoli, Camilla Evangelisti, Stefano Ratti
Publikováno v:
Journal of Orthopaedic Translation, Vol 47, Iss , Pp 116-124 (2024)
Osteoarthritis (OA) is one of the most common disabling pathologies, characterized by joint pain and reduced function, significantly worsening the quality of life. Even if important progresses have been made in OA research, little is yet known about
Externí odkaz:
https://doaj.org/article/998c8b7063d94ebb8a595a83705689ff
Autor:
Antonietta Fazio, Irene Neri, Foteini-Dionysia Koufi, Maria Vittoria Marvi, Andrea Galvani, Camilla Evangelisti, James A. McCubrey, Lucio Cocco, Lucia Manzoli, Stefano Ratti
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6592 (2024)
Pericytes are multipotent cells embedded within the vascular system, primarily surrounding capillaries and microvessels where they closely interact with endothelial cells. These cells are known for their intriguing properties due to their heterogenei
Externí odkaz:
https://doaj.org/article/3fb2bf99c3554c7884997f2c480bb881
Autor:
Niels Pietsch, Jiancheng Cheng, Antonietta Fazio, Leonie Ewald, Erda Alizoti, Elisabeth Krämer, Ellen Orthey, Lucie Carrier, Sonia R Singh
Publikováno v:
Stem Cell Research, Vol 71, Iss , Pp 103188- (2023)
Variants in CRYAB can lead to desmin-related (cardio-)myopathy (DRM), a genetic muscle disorder with no curative treatment available. We introduced a homozygous CRYAB c.358G > A (p.Arg120Gly) mutation, which is established for the study of DRM in mic
Externí odkaz:
https://doaj.org/article/690b5a4cbefd4b42b1db8d1852a43c94
Autor:
Foteini-Dionysia Koufi, Irene Neri, Giulia Ramazzotti, Isabella Rusciano, Sara Mongiorgi, Maria Vittoria Marvi, Antonietta Fazio, Minkyung Shin, Yoichi Kosodo, Ilaria Cani, Elisa Giorgio, Pietro Cortelli, Lucia Manzoli, Stefano Ratti
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Lamin B1 is an essential protein of the nuclear lamina that plays a crucial role in nuclear function and organization. It has been demonstrated that lamin B1 is essential for organogenesis and particularly brain development. The important role of lam
Externí odkaz:
https://doaj.org/article/4930a394323e4810b2513ff640342165
Autor:
Francesca Chiarini, Francesca Paganelli, Tommaso Balestra, Cristina Capanni, Antonietta Fazio, Maria Cristina Manara, Lorena Landuzzi, Stefania Petrini, Camilla Evangelisti, Pier-Luigi Lollini, Alberto M. Martelli, Giovanna Lattanzi, Katia Scotlandi
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-13 (2022)
Abstract Lamin A, a main constituent of the nuclear lamina, is involved in mechanosignaling and cell migration through dynamic interactions with the LINC complex, formed by the nuclear envelope proteins SUN1, SUN2 and the nesprins. Here, we investiga
Externí odkaz:
https://doaj.org/article/5d5b516d43e64786927cb4086677f8b3
Autor:
Antonietta Fazio, Camilla Evangelisti, Alessandra Cappellini, Sara Mongiorgi, Foteini-Dionysia Koufi, Irene Neri, Maria Vittoria Marvi, Michele Russo, Alessandra Ghigo, Lucia Manzoli, Roberta Fiume, Stefano Ratti
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13096 (2023)
Phospholipase C (PLC) enzymes represent crucial participants in the plasma membrane of mammalian cells, including the cardiac sarcolemmal (SL) membrane of cardiomyocytes. They are responsible for the hydrolysis of phosphatidylinositol 4,5-bisphosphat
Externí odkaz:
https://doaj.org/article/8cf969a1f27f49c28f19bc0395a38106
Autor:
Magdalena C. Vidalle, Bhavwanti Sheth, Antonietta Fazio, Maria Vittoria Marvi, Stefano Leto, Foteini-Dionysia Koufi, Irene Neri, Irene Casalin, Giulia Ramazzotti, Matilde Y. Follo, Stefano Ratti, Lucia Manzoli, Sonakshi Gehlot, Nullin Divecha, Roberta Fiume
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1049 (2023)
Polyphosphoinositides (PPIns) are signalling messengers representing less than five per cent of the total phospholipid concentration within the cell. Despite their low concentration, these lipids are critical regulators of various cellular processes,
Externí odkaz:
https://doaj.org/article/8acd71ceb0e847d2bbd9c07c1de8f78d
Autor:
Stefano Ratti, Camilla Evangelisti, Sara Mongiorgi, Alessia De Stefano, Antonietta Fazio, Francesca Bonomini, Matilde Y. Follo, Irene Faenza, Lucia Manzoli, Bhavwanti Sheth, Magdalena C. Vidalle, Scott T. Kimber, Nullin Divecha, Lucio Cocco, Roberta Fiume
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Polyphosphoinositides (PPIns) and their modulating enzymes are involved in regulating many important cellular functions including proliferation, differentiation or gene expression, and their deregulation is involved in human diseases such as metaboli
Externí odkaz:
https://doaj.org/article/3ead2fc287554aff929f02b3b756f2b8
Autor:
Jaskarndip Chahal, Alejandro Gómez‐Aristizábal, Konstantin Shestopaloff, Shashank Bhatt, Amélie Chaboureau, Antonietta Fazio, Jolene Chisholm, Amanda Weston, Julia Chiovitti, Armand Keating, Mohit Kapoor, Darrell J. Ogilvie‐Harris, Khalid A. Syed, Rajiv Gandhi, Nizar N. Mahomed, Kenneth W. Marshall, Marshall S. Sussman, Ali M. Naraghi, Sowmya Viswanathan
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 8, Pp 746-757 (2019)
Abstract Patients with late‐stage Kellgren‐Lawrence knee osteoarthritis received a single intra‐articular injection of 1, 10, or 50 million bone marrow mesenchymal stromal cells (BM‐MSCs) in a phase I/IIa trial to assess safety and efficacy u
Externí odkaz:
https://doaj.org/article/da7441f8b4b143e1aabd7d85cd211f75
Autor:
Sarah Parisi, Carlo Finelli, Antonietta Fazio, Alessia De Stefano, Sara Mongiorgi, Stefano Ratti, Alessandra Cappellini, Anna Maria Billi, Lucio Cocco, Matilde Y. Follo, Lucia Manzoli
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 827 (2021)
Erythropoiesis regulation is essential in normal physiology and pathology, particularly in myelodysplastic syndromes (MDS) and β-thalassemia. Several signaling transduction processes, including those regulated by inositides, are implicated in erythr
Externí odkaz:
https://doaj.org/article/26a218d57f1049c1910b5bc2f9e142a7