Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Antonieta Capdevila"'
Autor:
Ingrid Alfheim, Raymond F. Burk, Frank Frantzen, Antonieta Capdevila, Joshua Freedman, Conrad Wagner
Publikováno v:
The Journal of Nutritional Biochemistry. 18:827-831
The measurement of plasma S-adenosylhomocysteine is a more sensitive indicator of the risk for vascular disease than is plasma homocysteine. Because the level of S-adenosylhomocysteine is normally in the nanomolar range, it has been difficult to meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3d66792c63543113a61f09ce3987ee
https://doi.org/10.1016/j.jnutbio.2007.01.003
https://doi.org/10.1016/j.jnutbio.2007.01.003
Publikováno v:
ResearcherID
Three human cases having mutations in the glycine N-methyltransferase (GNMT) gene have been reported. This enzyme transfers a methyl group from S-adenosylmethionine (SAM) to glycine to form S-adenosylhomocysteine (SAH) and N-methylglycine (sarcosine)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f78c49026e8cc5a1c398103b9ed01a
https://doi.org/10.1007/s11248-006-0008-1
https://doi.org/10.1007/s11248-006-0008-1
Autor:
David R. Maneval, Bonnie S. Coats, Jesse F. Gregory, Karla P. Shelnutt, Haifa Ghandour, Antonieta Capdevila, Lynn B. Bailey, Peter W. Stacpoole, Jacob Selhub, Eoin P. Quinlivan, Jonathan J. Shuster, Steven R. Davis, Conrad Wagner
Publikováno v:
The Journal of Nutrition. 135:1040-1044
Whether folate status and the methylenetetrahydrofolate reductase (MTHFR) 677C-->T polymorphism interact to affect methionine-cycle metabolite concentrations is uncertain. We evaluated the effects of dietary folate restriction on relations among fola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95696db6b62dd1125108cbf810da6f36
https://doi.org/10.1093/jn/135.5.1040
https://doi.org/10.1093/jn/135.5.1040
Publikováno v:
The American Journal of Clinical Nutrition. 74:723-729
BACKGROUND Although plasma total homocysteine has been identified as an independent risk factor for vascular disease in a multitude of studies, there is a considerable overlap in values between patients at risk and control subjects. The difference in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8586b6903059c2a9315319d6b7aa6cdd
https://doi.org/10.1093/ajcn/74.6.723
https://doi.org/10.1093/ajcn/74.6.723
Autor:
Antonieta Capdevila, Margareth Roch, Donald J. Jenden, S. Harvey Mudd, Harvey L. Levy, Conrad Wagner
Publikováno v:
Metabolism. 49:1542-1547
The concentrations of methionine and S-adenosylmethionine (AdoMet) in plasma and free choline and phospholipid-bound choline in both plasma and red blood cells from individuals with isolated hypermethioninemia have been measured. The only genetic abn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68d46ca209e79ce34bba2d5f49fad92
https://doi.org/10.1053/meta.2000.18521
https://doi.org/10.1053/meta.2000.18521
Autor:
Conrad Wagner, Antonieta Capdevila
Publikováno v:
Analytical Biochemistry. 264:180-184
The low levels of S-adenosylmethionine (AdoMet) and S-adenosylhomocysteine (AdoHcy) in plasma can be measured by formation of the fluorescent isoindole derivatives of these compounds. The procedure involves an initial separation of AdoMet and AdoHcy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f68e5d16582bb37fbc1f2a3fdb774b
https://doi.org/10.1006/abio.1998.2839
https://doi.org/10.1006/abio.1998.2839
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice
Autor:
Conrad Wagner, M. Luz Martínez-Chantar, Mario F. Fraga, Marta Varela, Rune Matthiesen, Ana M. Aransay, Juan Pedro Febles Rodríguez, Zigmund Luka, Heping Yang, Shelly C. Lu, Nuria Martínez, Diego F. Calvisi, Antonieta Capdevila, Mercedes Vazquez-Chantada, José M. Mato, Manel Esteller, Usue Ariz
Publikováno v:
ResearcherID
Glycine N-methyltransferase (GNMT) is the main enzyme responsible for catabolism of excess hepatic S-adenosylmethionine (SAMe). GNMT is absent in hepatocellular carcinoma (HCC), messenger RNA (mRNA) levels are significantly lower in livers of patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a984b04a6ce25ce2d09a95ec5dc6a67c
https://pubmed.ncbi.nlm.nih.gov/19475685
https://pubmed.ncbi.nlm.nih.gov/19475685
Autor:
Conrad Wagner, Peter W. Stacpoole, Barry Shane, Eoin P. Quinlivan, Haifa Ghandour, Antonieta Capdevila, Jonathan J. Shuster, Jacob Selhub, Karla P. Shelnutt, Lynn B. Bailey, Steven R. Davis, Jesse F. Gregory, Bonnie S. Coats
Publikováno v:
The Journal of nutrition. 135(5)
The effects of folate status and the methylenetetrahydrofolate reductase (MTHFR) 677C-->T polymorphism on the kinetics of homocysteine metabolism are unclear. We measured the effects of dietary folate restriction on the kinetics of homocysteine remet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca369924456bd6ac455f4cbdf542b1f
https://pubmed.ncbi.nlm.nih.gov/15867279
https://pubmed.ncbi.nlm.nih.gov/15867279
Autor:
Albert Tangerman, M. C. Schiaffino, Sally P. Stabler, David Watkins, Ubaldo Caruso, N. Matiaszuk, A. R. Fantasia, Leighton LeGros, David S. Rosenblatt, Malak Kotb, James D. Finkelstein, Antonieta Capdevila, Roberto Cerone, B. Schwahn, Robert H. Allen, Conrad Wagner, Zigmund Luka, G. Minniti, Rima Rozen, S. H. Mudd, Renata Lorini
Publikováno v:
Journal of Inherited Metabolic Disease, 24, 448--64
Journal of Inherited Metabolic Disease, 24, 4, pp. 448--64
Journal of Inherited Metabolic Disease, 24, 4, pp. 448--64
Item does not contain fulltext This paper reports clinical and metabolic studies of two Italian siblings with a novel form of persistent isolated hypermethioninaemia, i.e. abnormally elevated plasma methionine that lasted beyond the first months of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a72493834814cdd22a09e86c9c800eb
http://hdl.handle.net/2066/185659
http://hdl.handle.net/2066/185659
Autor:
Conrad Wagner, Waraporn Decha-Umphai, Kyung-Hee Song, Ronald T. Borchardt, Antonieta Capdevila
Publikováno v:
Archives of biochemistry and biophysics. 345(1)
A number of early experiments suggested a relationship between methyl group metabolism and the exocrine secretion of the pancreas. These included nutritional studies showing that ethionine, the ethyl analog of methionine which inhibits cellular methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350a919f387518ea931f5878503108d4
https://pubmed.ncbi.nlm.nih.gov/9281310
https://pubmed.ncbi.nlm.nih.gov/9281310