Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Antonia Wallrapp"'
Autor:
Vijay Kuchroo, Yu Hou, Martin LaFleur, Linglin Huang, Conner Lambden, Pratiksha Thakore, Kathryn Geiger-Schuller, Ruihan Tang, Jingwen Shi, Rocky Barilla, Ayshwarya Subramanian, Antonia Wallrapp, Hee Sun Choi, Yoon-Chul Kye, Orr Ashenbrg, Geoffrey Schiebinger, John Doench, Aviv Regev, Arlene Sharpe
The balance between T helper type 1 (Th1) cells and other Th cells is critical for antiviral and anti-tumor responses, but how this fine balance is achieved remains poorly understood. Here, we dissected the dynamic regulation of Th1 cell differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f73a53d2c34de40f858520400f4428e
https://doi.org/10.21203/rs.3.rs-1953978/v1
https://doi.org/10.21203/rs.3.rs-1953978/v1
Publikováno v:
Trends in neurosciences. 45(4)
In the gut, coordinated cell interactions regulate tissue repair and immunity. How enteric glial cells (EGCs) mediate these processes remained elusive. In a recent paper, Progatzky et al. demonstrate that EGCs interact with immune and mesothelial cel
Autor:
David DeTomaso, Yvonne C. Lee, Ana C. Anderson, Vijay K. Kuchroo, Nir Yosef, Patrick R. Burkett, Danielle Dionne, Antonia Wallrapp, Meyer zu Horste G, Aviv Regev, Ramnik J. Xavier, Jackson Nyman, Chao Wang, Mathias Pawlak, Samantha J. Riesenfeld
SummaryThe cytokine receptor IL-23R plays a fundamental role in inflammation and autoimmunity. However, several observations have been difficult to reconcile under the assumption that only Th17 cells critically depend on IL-23 to acquire a pathogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc05cb90675c3d4c9d0f53a8647add49
https://doi.org/10.1101/2021.01.24.426445
https://doi.org/10.1101/2021.01.24.426445
Autor:
Aditya Misra, Chuan Wu, Felipe A. Pinho-Ribeiro, Salima Soualhi, Melissa A. Musser, Donggi Paik, Meenakshi Rao, Dingding An, Pankaj Baral, Amanda Jacobson, Neeraj K. Surana, Kisha N. Sivanathan, Hailian Shi, Anja Nordstrom, Michael N. Starnbach, Jun R. Huh, Yiqing Yan, Pingchuan Ma, David E. Potts, Roni Nowarski, Zuojia Chen, Nicole Y. Lai, Valentina N. Lagomarsino, Isaac M. Chiu, Kaitlin Goldstein, Antonia Wallrapp, Vijay K. Kuchroo
Publikováno v:
Cell
Gut-innervating nociceptor sensory neurons respond to noxious stimuli by initiating protective responses including pain and inflammation; however, their role in enteric infections is unclear. Here, we find that nociceptor neurons critically mediate h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318e18b31759b6272e1a3f1bfadb38c5
https://europepmc.org/articles/PMC6954329/
https://europepmc.org/articles/PMC6954329/
Autor:
Pankaj Baral, Patrick R. Burkett, Daneyal Farouq, David Artis, Brian J. Haas, Bruce D. Levy, Jackson Nyman, John J. Trombetta, Antonia Wallrapp, Monika S. Kowalczyk, Timothy L. Tickle, Vijay K. Kuchroo, Samantha J. Riesenfeld, Christoph S.N. Klose, Christopher Rodman, Michael S. Cuoco, Orit Rozenblatt-Rosen, Aviv Regev, Danielle Dionne, Raja-Elie E. Abdulnour, Matan Hofree, Tanel Mahlakõiv, Isaac M. Chiu
Publikováno v:
Nature. 549:351-356
Type 2 innate lymphoid cells (ILC2s) both contribute to mucosal homeostasis and initiate pathologic inflammation in allergic asthma. However, the signals that direct ILC2s to promote homeostasis versus inflammation are unclear. To identify such molec
Autor:
Aviv Regev, Antonia Wallrapp, Jiarui Ding, Orit Rozenblatt-Rosen, Samantha J. Riesenfeld, Sai Ma, Shujie Fu, Patrick R. Burkett, Chien-wen Su, Hai Ning Shi, Daniel B. Graham, Danielle Dionne, Vijay K. Kuchroo, Marcin Tabaka, Caroline B. M. Porter, Xu Heping, Lan T. Nguyen, Orr Ashenberg, Ramnik J. Xavier, Xuanxuan Guo, Ariel Lefkovith
Publikováno v:
Prof. Regev via Courtney Crummett
Summary Signaling abnormalities in immune responses in the small intestine can trigger chronic type 2 inflammation involving interaction of multiple immune cell types. To systematically characterize this response, we analyzed 58,067 immune cells from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207acc737e8ef0bcf7f8ea4c72c906c2
https://hdl.handle.net/1721.1/126748
https://hdl.handle.net/1721.1/126748
Autor:
Alan Fine, Fengzhi Shao, Kenneth G. Trieu, Wei Wang, Xingbin Ai, Jonathan A. Cohen, Juliana Barrios, Yan Bai, Antonia Wallrapp, Vijay K. Kuchroo, Matthew R. Jones, Nandini Krishnamoorthy
Publikováno v:
Immunity. 51(6)
Summary Young children are more susceptible to developing allergic asthma than adults. As neural innervation of the peripheral tissue continues to develop after birth, neurons may modulate tissue inflammation in an age-related manner. Here we showed
Autor:
Samantha J. Riesenfeld, Rebecca H. Herbst, Pavana Khan, Bruce D. Levy, Antonia Wallrapp, Aviv Regev, Conner Lambden, Patrick R. Burkett, Kazutake Tsujikawa, Alexandra Schnell, Pratiksha I. Thakore, Isaac M. Chiu, Kim Se-Jin, Vijay K. Kuchroo, Raja-Elie E. Abdulnour, Ramnik J. Xavier, Elena Christian
Publikováno v:
Prof. Regev via Courtney Crummett
Immunity
Immunity
Summary Neuroimmune interactions have emerged as critical modulators of allergic inflammation, and type 2 innate lymphoid cells (ILC2s) are an important cell type for mediating these interactions. Here, we show that ILC2s expressed both the neuropept
Autor:
Donggi Paik, Goldstein K, Isaac M. Chiu, Meenakshi Rao, Potts De, Neeraj K. Surana, Huwenbo Shi, Aditya Misra, Catherine J. Wu, Zhicheng Chen, Huh, Soualhi S, Roni Nowarski, Antonia Wallrapp, Kisha N. Sivanathan, Ping Ma, Vijay K. Kuchroo, Lagomarsino, Amanda Jacobson, Nicole Y. Lai, Dingding An, Pankaj Baral, Michael N. Starnbach, Felipe A. Pinho-Ribeiro, Melissa A. Musser
SUMMARYGut-innervating nociceptor sensory neurons respond to noxious/tissue-damaging stimuli by initiating protective responses and releasing mediators that regulate tissue inflammation, gastrointestinal secretion, and motility. The role of nocicepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751c07616da4d16eff0f7ad460da4027
https://doi.org/10.1101/580555
https://doi.org/10.1101/580555
Publikováno v:
Immunol Rev
Type 2 immunity against pathogens is tightly regulated to ensure appropriate inflammatory responses that clear infection and prevent excessive tissue damage. Recent research has shown that type 2 innate lymphoid cells (ILC2s) contribute to steady-sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27871d82150bb57f51027997c4c9a50
https://europepmc.org/articles/PMC7370855/
https://europepmc.org/articles/PMC7370855/