Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Antonia T. do-Amaral"'
Autor:
Erika Piccirillo, Thiago G P Alegria, Karen F Discola, José R R Cussiol, Renato M Domingos, Marcos A de Oliveira, Leandro de Rezende, Luis E S Netto, Antonia T-do Amaral
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196918 (2018)
Organic hydroperoxide resistance (Ohr) enzymes are highly efficient Cys-based peroxidases that play central roles in bacterial response to fatty acid hydroperoxides and peroxynitrite, two oxidants that are generated during host-pathogen interactions.
Externí odkaz:
https://doaj.org/article/99244d479e80482aa4aa579b00b09e4a
Autor:
Lucas G. Viviani, Erika Piccirillo, Arquimedes Cheffer, Leandro de Rezende, Henning Ulrich, Ana Maria Carmona-Ribeiro, Antonia T.-do Amaral
Publikováno v:
Molecules, Vol 23, Iss 8, p 1876 (2018)
Promiscuous inhibition due to aggregate formation has been recognized as a major concern in drug discovery campaigns. Here, we report some aggregators identified in a virtual screening (VS) protocol to search for inhibitors of human ecto-5′-nucleot
Externí odkaz:
https://doaj.org/article/2be8da1c474d48bca2d8e63868a1ffdf
Autor:
Alberto Malvezzi, Patrícia M Higa, Antonia T-do Amaral, Gustavo M Silva, Fabio C Gozzo, Emer S Ferro, Leandro M Castro, Leandro de Rezende, Gisele Monteiro, Marilene Demasi
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39408 (2012)
Thimet oligopeptidase (EP24.15) is a cysteine-rich metallopeptidase containing fifteen Cys residues and no intra-protein disulfide bonds. Previous work on this enzyme revealed that the oxidative oligomerization of EP24.15 is triggered by S-glutathiol
Externí odkaz:
https://doaj.org/article/d1eb6ac02a524b949c397368b1d21451
Publikováno v:
Journal of Medicinal Chemistry. 44:3673-3681
Three sets of antibacterial nitrofuran derivatives [set I, 5-R-substituted (Z)-2-(5-nitrofuran-2-ylmethylene)-3(2H)-benzofuranones (R = OCH(3), H, CH(3), C(2)H(5), nC(3)H(7), Cl, Br, CN, and NO(2)) and their 2-hydroxyphenyl and 2-acetoxyphenyl analog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9265920c941892f0e150145c2aa8f3a
https://doi.org/10.1021/jm0101693
https://doi.org/10.1021/jm0101693
Publikováno v:
ChemInform. 33
Three sets of antibacterial nitrofuran derivatives [set I, 5-R-substituted (Z)-2-(5-nitrofuran-2-ylmethylene)-3(2H)-benzofuranones (R = OCH3, H, CH3, C2H5, nC3H7, Cl, Br, CN, and NO2) and their 2-hydroxyphenyl and 2-acetoxyphenyl analogues; set II, 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa2f6ca960de96c1f4e7325283692bdb
https://doi.org/10.1002/chin.200209111
https://doi.org/10.1002/chin.200209111
Autor:
Ohara Augusto, Antonia T. do-Amaral, Giselle Cerchiaro, Alberto Malvezzi, Danilo B. Medinas, José Carlos de Toledo, Leandro de-Rezende
Publikováno v:
Chemical research in toxicology. 22(4)
Despite being one of the most important antioxidant defenses, Cu,Zn-superoxide dismutase (Sod1) has been frequently associated with harmful effects, including neurotoxicity. This toxicity has been attributed to immature forms of Sod1 and extraneous c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078c70e0c059e18dec1e0d805ecb0c18
https://pubmed.ncbi.nlm.nih.gov/19243126
https://pubmed.ncbi.nlm.nih.gov/19243126
Publikováno v:
Molecular Modeling and Prediction of Bioactivity ISBN: 9781461368571
The antimicrobial activity of nitroaromatic compounds requires and is related to an enzymatic reduction of the nitro group in vivo, yielding toxic species1. In the present work, QSAR analysis of nine 5-X-substituted 2-(5-nitro-2-furfurilidene)-3-oxo-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::725c4343aaf56174275c5f8c17ea7174
https://doi.org/10.1007/978-1-4615-4141-7_45
https://doi.org/10.1007/978-1-4615-4141-7_45
