Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Antonia Sassmann"'
2
Disease Progression and Age as Factors Underlying Multimorbidity in Patients with COPD
Autor: Peter Alter, Kathrin Kahnert, Franziska C Trudzinski, Robert Bals, Henrik Watz, Tim Speicher, Sandra Söhler, Stefan Andreas, Tobias Welte, Klaus F Rabe, Emiel FM Wouters, Antonia Sassmann-Schweda, Hubert Wirtz, Joachim H Ficker, Claus F Vogelmeier, Rudolf A Jörres
Publikováno v: International journal of chronic obstructive pulmonary disease, 17, 1703-1713. Dove Medical Press Ltd
Peter Alter,1 Kathrin Kahnert,2 Franziska C Trudzinski,3 Robert Bals,4 Henrik Watz,5 Tim Speicher,1 Sandra Söhler,1 Stefan Andreas,6 Tobias Welte,7 Klaus F Rabe,8 Emiel FM Wouters,9 Antonia Sassmann-Schweda,10 Hubert Wirtz,11 Joachim H Ficker,12,1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6abe88508376bfaa1b5b471861f1a327
https://doi.org/10.2147/copd.s364812
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3
Changes in taste and smell as an early marker for COVID-19
Autor: Jan Heyckendorf, Rick Shaikh, Johanna Eggeling, Maja Reimann, Christina Maier, Mareike Luethgen, Christian Herzmann, Christoph Lange, Antonia Sassmann-Schweda
Publikováno v: International journal of infectious diseases, 99:8-9
International Journal of Infectious Diseases, Vol 99, Iss, Pp 8-9 (2020)
International Journal of Infectious Diseases
Highlights • Neurosensory dysfunction • Chronological analysis • Viral load
Objectives To detailly described the neurosensory dysfunction, including hyposmia, hypogeusia and tinnitus, in patients with COVID-19. Methods Clinical characteris
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef1d74f6af70b7acebfc0645da8c13f
https://repository.publisso.de/resource/frl:6424129
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4
Increased cGMP promotes healthy expansion and browning of white adipose tissue
Autor: Thorsten Gnad, Daniela Scholz, Michaela M. Mitschke, Peter Mayer, Bodo Haas, Katja Kruithoff, Linda S. Hoffmann, Antonia Sassmann, Alexander Pfeifer, Ana Kilić
Publikováno v: The FASEB Journal. 27:1621-1630
With more than half a billion individuals affected worldwide, obesity has reached pandemic proportions. Development of "brown-like" or "brite" adipocytes within white adipose tissue (WAT) has potential antiobesity and insulin-sensitizing effects. We
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc85028a01582356de9e90f196ccac13
https://doi.org/10.1096/fj.12-221580
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5
Increased apoptosis and browning of TAK1-deficient adipocytes protects against obesity
Autor: Pratibha Singh, Nina Wettschureck, Antonia Sassmann-Schweda, Astrid Wietelmann, Stefan Offermanns, Cong Tang
Publikováno v: JCI Insight. 1
Obesity is an increasing health problem worldwide, and nonsurgical strategies to treat obesity have remained rather inefficient. We here show that acute loss of TGF-β-activated kinase 1 (TAK1) in adipocytes results in an increased rate of apoptotic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317faea3f5c1d2ab6be1eac84aa57805
https://doi.org/10.1172/jci.insight.81175
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6
The Gq/G11-mediated signaling pathway is critical for autocrine potentiation of insulin secretion in mice
Autor: Stefan Offermanns, Gisela Drews, Nina Wettschureck, Antonia Sassmann, Hermann Josef Gröne, Belinda Gier
Publikováno v: Journal of Clinical Investigation. 120:2184-2193
A variety of neurotransmitters, gastrointestinal hormones, and metabolic signals are known to potentiate insulin secretion through GPCRs. We show here that beta cell-specific inactivation of the genes encoding the G protein alpha-subunits Galphaq and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b39bea7856ba226340783d397d72eb
https://doi.org/10.1172/jci41541
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7
Guanine Nucleotide-Binding Proteins of the G12 Family Shape Immune Functions by Controlling CD4+ T Cell Adhesiveness and Motility
Autor: Peter Reichardt, Nancy Hogg, Klaus-Dieter Fischer, Stefan Offermanns, Markus W. Hollmann, Nina Wettschureck, Matthias Gunzer, Antonia Sassmann, Dagmar Jaeneke, Barbara Zimmermann, Robert Grosse, Jana Hoeckner, Stephan Vogt, Susanne Herroeder
Publikováno v: Immunity, 30(5), 708-720. Cell Press
Integrin-mediated adhesion plays a central role in T cell trafficking and activation. Genetic inactivation of the guanine nucleotide-binding (G) protein alpha-subunits G alpha(12) and G alpha(13) resulted in an increased activity of integrin leukocyt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93df788f34eb6ffce58023dca21074f7
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8
Tamoxifen-inducible Cre-mediated recombination in adipocytes
Autor: Nina Wettschureck, Antonia Sassmann, Stefan Offermanns
Publikováno v: Genesis (New York, N.Y. : 2000). 48(10)
To generate a mouse line which allows inducible, Cre/loxP-dependent recombination in adipocytes, we used RedE/RedT-mediated recombineering to insert the CreER(T)²-transgene, which encodes a fusion protein of Cre and a mutated tamoxifen-responsive es
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d560012f3dbbcaea656efd02d959649b
https://pubmed.ncbi.nlm.nih.gov/20715175
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9
Expression of nitric oxide synthase isoforms in hypothalamo-pituitary-adrenal axis during the development of spontaneous hypertension in rats
Autor: Olaf Jöhren, Antonia Sassmann, Fatimunnisa Qadri, Peter Dominiak, Walter Häuser
Publikováno v: Brain research. Molecular brain research. 138(2)
This study was performed to investigate the expression of the major isoforms of nitric oxide synthase mRNA and protein in the hypothalamo-pituitary-adrenal axis (HPA axis) of spontaneously hypertensive rats (SHR) at two different postnatal ages corre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60ae8db1874ee4b6a39229ce4400cbe
https://pubmed.ncbi.nlm.nih.gov/15913838
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10
PAR1 Scaffolds TGFβRII to Downregulate TGF-β Signaling and Activate ESC Differentiation to Endothelial Cells
Autor: Haixia Gong, Manish Mittal, Menglin Liu, Stefan Offermanns, Wei Zhang, Asrar B. Malik, Zhigang Hong, Antonia Sassmann, Jalees Rehman, Victoria Mastej, She-Juan An
Publikováno v: Stem Cell Reports
Summary We studied the function of the G-protein-coupled receptor PAR1 in mediating the differentiation of mouse embryonic stem cells (mESCs) to endothelial cells (ECs) that are capable of inducing neovascularization. We observed that either deletion
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08a1ae71e5a7f12bfb6fff21b270eb1
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