Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Antonia Reale"'
Autor:
Fabrice Lucien, Dakota Gustafson, Metka Lenassi, Bo Li, Jacob J. Teske, Eric Boilard, Katharina Clemm vonHohenberg, Juan Manual Falcón‐Perez, Alice Gualerzi, Antonia Reale, Jennifer C. Jones, Cecilia Lässer, Charlotte Lawson, Irina Nazarenko, Lorraine O'Driscoll, Ryan Pink, Pia R‐M Siljander, Carolina Soekmadji, An Hendrix, Joshua A Welsh, Kenneth W. Witwer, Rienk Nieuwland
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 12, Pp n/a-n/a (2023)
Abstract Blood is the most commonly used body fluid for extracellular vesicle (EV) research. The composition of a blood sample and its derivatives (i.e., plasma and serum) are not only donor‐dependent but also influenced by collection and preparati
Externí odkaz:
https://doaj.org/article/010fcc3dbbc8418bb52f5676920d8ecb
Autor:
Aurelia Lamanuzzi, Ilaria Saltarella, Antonia Reale, Assunta Melaccio, Antonio Giovanni Solimando, Concetta Altamura, Grazia Tamma, Clelia Tiziana Storlazzi, Doron Tolomeo, Vanessa Desantis, Maria Addolorata Mariggiò, Jean-François Desaphy, Andrew Spencer, Angelo Vacca, Benedetta Apollonio, Maria Antonia Frassanito
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1400 (2023)
Extracellular vesicles (EVs) have emerged as important players in cell-to-cell communication within the bone marrow (BM) of multiple myeloma (MM) patients, where they mediate several tumor-associated processes. Here, we investigate the contribution o
Externí odkaz:
https://doaj.org/article/53691e10e7164ed6be018791decbb9fc
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The cross-talk between tumour cells and stromal cells is a hallmark of multiple myeloma (MM), a blood cancer that still remains incurable despite increased knowledge of its biology and advances in its treatment. Extracellular vesicles (EVs) derived f
Externí odkaz:
https://doaj.org/article/9e85faf8f5974ebaaa85ec8781f09403
Autor:
Antonia Reale, Assunta Melaccio, Aurelia Lamanuzzi, Ilaria Saltarella, Franco Dammacco, Angelo Vacca, Roberto Ria
Publikováno v:
Stem Cells International, Vol 2016 (2016)
It was believed that vasculogenesis occurred only during embryo life and that postnatal formation of vessels arose from angiogenesis. Recent findings demonstrate the existence of Endothelial Precursor Cells (EPCs), which take partin postnatal vasculo
Externí odkaz:
https://doaj.org/article/5d051b160bdd4a7a9dc6a2d1b79e325c
Autor:
Ivana Catacchio, Simona Berardi, Antonia Reale, Annunziata De Luisi, Vito Racanelli, Angelo Vacca, Roberto Ria
Publikováno v:
Stem Cells International, Vol 2013 (2013)
In contrast to the pluripotent embryonic stem cells (ESCs) which are able to give rise to all cell types of the body, mammalian adult stem cells (ASCs) appeared to be more limited in their differentiation potential and to be committed to their tissue
Externí odkaz:
https://doaj.org/article/5a14b7dd659c462086eb315b26ad7cf9
Autor:
Roberto Ria, Antonia Reale, Antonio Giovanni Solimando, Giuseppe Mangialardi, Michele Moschetta, Lucia Gelao, Giuseppe Iodice, Angelo Vacca
Publikováno v:
Stem Cells International, Vol 2012 (2012)
Autologous stem cell transplantation (ASCT) is considered the standard therapy for younger patients with newly diagnosed symptomatic multiple myeloma (MM). The introduction into clinical practice of novel agents, such as the proteasome inhibitor bort
Externí odkaz:
https://doaj.org/article/b490d8e82533446f894f5b3dc78e57fa
Publikováno v:
Journal of clinical medicine. 11(23)
Tumor cells actively incorporate molecules (e.g., proteins, lipids, RNA) into particles named extracellular vesicles (EVs). Several groups have demonstrated that EVs can be transferred to target (recipient) cells, making EVs an important means of int
Publikováno v:
Leukemia. 35:2771-2783
Liquid biopsies-a source of circulating cell-free nucleic acids, proteins and extracellular vesicles-are currently being explored for the quantitative and qualitative characterisation of the tumour genome and as a mode of non-invasive therapeutic mon
Autor:
Antonia Reale, Rong Xu, Irena Carmichael, Haoyun Fang, Jaynish S Sha, Tiffany Khong, Nicholas Bingham, Malarmathy Ramachandran, Maoshan Chen, David W Greening, Andrew Spencer
Publikováno v:
Cancer Research. 83:2366-2366
Background: We have shown that human stromal cells (HS5) treated with small extracellular vesicles (EV) derived from plasma of myeloma (MM) patients (MM-EV) promoted adhesion of human MM cell lines (HMCL), with preliminary proteomic profiling of MM-
Autor:
Nicholas E. Bingham, Jaynish Shah, Antonia Reale, Daniel Wong, Tiffany Khong, Sridurga Mithraprabhu, Andrew Spencer
Publikováno v:
Cancer Research. 83:2225-2225
Background: Extramedullary disease (EMD) affects 30% of multiple myeloma (MM) patients, predicting poor overall survival due to aggressive disease kinetics and multi-drug resistance. Understanding EMD genomics may inform targeted treatment approaches