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pro vyhledávání: '"Antonia R Bass"'
Autor:
Antonia R. Bass, Marisa S. Egan, Jasmine Alexander-Floyd, Natasha Lopes Fischer, Jessica Doerner, Sunny Shin
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT The inflammasome is essential for host defense against intracellular bacterial pathogens, including Legionella pneumophila, the causative agent of the severe pneumonia Legionnaires’ disease. Inflammasomes recruit and activate caspases, whi
Externí odkaz:
https://doaj.org/article/aaf626656445465281591767045e51d3
Autor:
Jasmine Alexander-Floyd, Antonia R. Bass, Erin M. Harberts, Daniel Grubaugh, Joseph D. Buxbaum, Igor E. Brodsky, Robert K. Ernst, Sunny Shin
Publikováno v:
Infect Immun
Detection of Gram-negative bacterial lipid A by the extracellular sensor, myeloid differentiation 2 (MD2)/Toll-like receptor 4 (TLR4), or the intracellular inflammasome sensors, CASP4 and CASP5, induces robust inflammatory responses. The chemical str
Autor:
Jasmine Alexander-Floyd, Antonia R. Bass, Erin M. Harberts, Daniel Grubaugh, Joseph D. Buxbaum, Igor E. Brodsky, Robert K. Ernst, Sunny Shin
Detection of Gram-negative bacterial lipid A by the extracellular sensor, MD-2/TLR4 or the intracellular inflammasome sensors, CASP4 and CASP5, induces robust inflammatory responses. The chemical structure of lipid A, specifically the phosphorylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6af5f98a62e5a95be2b44df7d68a63e
https://doi.org/10.1101/2021.12.16.472937
https://doi.org/10.1101/2021.12.16.472937
Autor:
Antonia R Bass, Sonya Kimball, Anjelica Jenkins, Aimee Burton, Katherine Trostle, Halea Corcoran, Meredith Allen, Catherine Gallagher, Jacque Harms, Andrew Bett, Nicole Sullivan
Publikováno v:
The Journal of Immunology. 208:50.01-50.01
Adjuvants are crucial components of subunit vaccines, as they help induce immune responses to poorly immunogenic antigens. Merck has developed a variety of lipid nanoparticles (LNPs) that contain different cationic lipids, a critical component that i