Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Antonia Orsi"'
Autor:
Antonia Orsi, Germano Oberto, Silvana Venturella, Daryl Rees, Isabella Andreini, Serena Cinelli
Publikováno v:
Regulatory Toxicology and Pharmacology
Callithrix jacchus (common marmoset) is one of the more primitive non-human primate species and is used widely in fundamental biology, pharmacology and toxicology studies. Marmosets breed well in captivity with good reproductive efficiencies and thei
Publikováno v:
Neurobiology of Aging. 31:1010-1019
The purpose of this work is to study the effect of smilagenin on the mRNA stability of muscarinic receptor subtype 1 (M(1); m1 mRNA) in aged rat brains and its significance in improving memory. The Y-maze avoidance task showed that oral administratio
Autor:
Tom H. Johnston, Noelle Callizot, Kimberly Dixon, Antonia Orsi, Daryl Rees, Naomi P. Visanji, Patrick A. Howson, Jonathan M. Brotchie
Publikováno v:
The FASEB Journal. 22:2488-2497
Many experimental data support the enhancement of neurotrophic factors as a means to modify neurodegeneration in Parkinson's disease. However, the translation of this to the clinic has proven problematic. This is likely due to the complex nature of t
Publikováno v:
FEBS Letters. 582:956-960
Tyrosine hydroxylase immunohistochemical analysis revealed that in cultured mesencephalic dopaminergic neurons smilagenin (SMI), added prior to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPP+), protected against the drop of neuron number and neuri
Publikováno v:
British Journal of Pharmacology. 129:953-960
The effect of prolonged exposure to nitric oxide on enzymes involved in cell metabolism was investigated in T lymphocyte-derived Jurkat and L929 fibroblast human cell lines using a constant concentration of nitric oxide (1.5 microM) released by the n
Autor:
Antonia Orsi, Belén Beltrán, Salvador Moncada, Martin Feelisch, Katarina Hallén, Emilio Clementi
Publikováno v:
Biochemical Journal. 346:407-412
Nitric oxide (NO) plays a key role in many physiological and pathophysiological events, including the control of cell respiration. Both reversible and irreversible inhibition of mitochondrial respiration have been reported following the generation of
Publikováno v:
Journal of Chromatography A. 689:97-105
In order to optimize the separation of DNA fragments, in the 50–500 base pairs (bp) range, a typical size interval of most polymerase chain reaction-amplified DNA chains produced for analysis of genetic diseases, different ways of preparing liquid
Publikováno v:
Journal of Chromatography A. 686:121-128
Various classes of calf thymus histones (fractions Il-AS, VI-S, VII-S and VIII-S) were separated to the steady state in an extremely alkaline immobilized pH gradient, covering non-linearly the pH 10–12 interval. Successful separations were obtained
Autor:
Cecilia Gelfi, Monica Zanussi, Pier Giorgio Righetti, Antonia Orsi, Maurizio Ferrari, Paola Carrera
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 657:201-205
The use of capillary zone electrophoresis (CZE) in polymer networks for the analysis of an 8 bp (base pair) deletion in congenital adrenal hyperplasia was investigated. Separations were performed in Tris-borate-EDTA buffer (pH 8.3) containing 6% liqu
Autor:
Roberta Bradford, Guus S M J E Duchateau, Winfried Theis, David J. Mela, Caroline L Ward, Salomon Leendert Abrahamse, Wendy A M Blom, Antonia Orsi
Publikováno v:
The American journal of clinical nutrition. 94(5)
Background: Extracts from Hoodia gordonii have been shown to decrease food intakes and body weights in animals and were proposed as a food supplement or ingredient for weight management. Objective: We assessed the safety and efficacy of a 15-d repeat