Killer Immunoglobulin-Like Receptor Profiles are not Associated with risk of Amoxicillin-Clavulanate-Induced Liver Injury in Spanish Patients

Autor: Camilla Stephens, Antonia Moreno-Casares, Miguel-Ángel López-Nevot, Miren García-Cortés, Inmaculada Medina-Cáliz, Hacibe Hallal, German Soriano, Eva Roman, Francisco Ruiz-Cabello, Manuel Romero-Gomez, M Isabel Lucena, Raúl J Andrade

Publikováno v: Frontiers in Pharmacology, Vol 7 (2016)

Natural killer cells are an integral part of the immune system and represent a large proportion of the lymphocyte population in the liver. The activity of these cells is regulated by various cell surface receptors, such as killer Ig-like receptors (K

Externí odkaz: https://doaj.org/article/52eb5d5afa794ac19682de663551d1b8

HLA Alleles Influence the Clinical Signature of Amoxicillin-Clavulanate Hepatotoxicity

Autor: Germán Soriano, Camilla Stephens, M.A. López-Nevot, Antonia Moreno-Casares, Manuel Romero-Gómez, M. Isabel Lucena, Francisco Ruiz-Cabello, Raúl J. Andrade, Eugenia Ulzurrun

Publikováno v: PLoS One
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Digibug. Repositorio Institucional de la Universidad de Granada
PLoS ONE, Vol 8, Iss 7, p e68111 (2013)
PLoS ONE

[Background and Aim] The genotype-phenotype interaction in drug-induced liver injury (DILI) is a subject of growing interest. Previous studies have linked amoxicillin-clavulanate (AC) hepatotoxicity susceptibility to specific HLA alleles. In this stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7081708672c56888c5e49f65e78fbaa
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=9803