Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Antonia Malinova"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Infidelity to cell fate occurs when differentiated cells lose their original identity and either revert to a more multipotent state or transdifferentiate into a different cell type, either within the same embryonic lineage or in an entirely different
Externí odkaz:
https://doaj.org/article/fcd242144c6d44caa733c5e01c4b254d
Autor:
Sabrina D’Agosto, Francesco Pezzini, Lisa Veghini, Pietro Delfino, Claudia Fiorini, Gael D. Temgue Tane, Anais Del Curatolo, Caterina Vicentini, Giorgia Ferrari, Davide Pasini, Silvia Andreani, Francesca Lupo, Elena Fiorini, Giulia Lorenzon, Rita T. Lawlor, Borislav Rusev, Antonia Malinova, Claudio Luchini, Michele Milella, Elisabetta Sereni, Antonio Pea, Claudio Bassi, Peter Bailey, Aldo Scarpa, Emilio Bria, Vincenzo Corbo
Publikováno v:
Oncogene. 41:4371-4384
Transcriptomic analyses of pancreatic ductal adenocarcinoma (PDAC) have identified two major epithelial subtypes with distinct biology and clinical behaviours. Here, we aimed to clarify the role of FGFR1 and FGFR4 in the definition of aggressive PDAC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1cf412d714bf3f99ee2a0c73add4bf
https://doi.org/10.1038/s41388-022-02432-5
https://doi.org/10.1038/s41388-022-02432-5
Autor:
Silve Vicent, Mariano Ponz-Sarvise, Vincenzo Corbo, Jens T. Siveke, Aldo Scarpa, Fernando Lecanda, Purvesh Khatri, Daniel Öhlund, Irati Macaya, Ester Blanco, Karmele Valencia, Haritz Moreno, Marija Trajkovic-Arsic, Pietro Delfino, Elizabeth Guruceaga, Caterina Vicentini, Antonia Malinova, Rodrigo Entrialgo-Cadierno, Iker Feliu, Shruthi Narayanan, Oihane Erice
Suppl. Figure 3. A. Immunoblot of LAMC2 upon Lamc2 knockdown by a specific shRNA in 511950 and PM12167 PDAC mouse cell lines. B. Quantification of organoid number upon LAMC2 knockdown by a specific shRNA in 511950 and PM12167 PDAC mouse cell lines.C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241af947e69570b728e188ae14ec23c1
https://doi.org/10.1158/1078-0432.22490566
https://doi.org/10.1158/1078-0432.22490566
Autor:
Silve Vicent, Mariano Ponz-Sarvise, Vincenzo Corbo, Jens T. Siveke, Aldo Scarpa, Fernando Lecanda, Purvesh Khatri, Daniel Öhlund, Irati Macaya, Ester Blanco, Karmele Valencia, Haritz Moreno, Marija Trajkovic-Arsic, Pietro Delfino, Elizabeth Guruceaga, Caterina Vicentini, Antonia Malinova, Rodrigo Entrialgo-Cadierno, Iker Feliu, Shruthi Narayanan, Oihane Erice
This file includes the Suppl. Methods, Table (1) and References
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2fb169155229fbe80a123105115489
https://doi.org/10.1158/1078-0432.22490548
https://doi.org/10.1158/1078-0432.22490548
Autor:
Silve Vicent, Mariano Ponz-Sarvise, Vincenzo Corbo, Jens T. Siveke, Aldo Scarpa, Fernando Lecanda, Purvesh Khatri, Daniel Öhlund, Irati Macaya, Ester Blanco, Karmele Valencia, Haritz Moreno, Marija Trajkovic-Arsic, Pietro Delfino, Elizabeth Guruceaga, Caterina Vicentini, Antonia Malinova, Rodrigo Entrialgo-Cadierno, Iker Feliu, Shruthi Narayanan, Oihane Erice
Purpose:The identification of pancreatic ductal adenocarcinoma (PDAC) dysregulated genes may unveil novel molecular targets entering inhibitory strategies. Laminins are emerging as potential targets in PDAC given their role as diagnostic and prognost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991d0dce0ccadf3f4d85d52da22204b0
https://doi.org/10.1158/1078-0432.c.6533179.v1
https://doi.org/10.1158/1078-0432.c.6533179.v1
Autor:
Francesca Lupo, Francesco Pezzini, Elena Fiorini, Annalisa Adamo, Lisa Veghini, Michele Bevere, Cristina Frusteri, Pietro Delfino, Sabrina D’Agosto, Silvia Andreani, Geny Piro, Antonia Malinova, Francesco De Sanctis, Davide Pasini, Rita T. Lawlor, Chang-il Hwang, Carmine Carbone, Ivano Amelio, Peter Bailey, Vincenzo Bronte, David Tuveson, Aldo Scarpa, Stefano Ugel, Vincenzo Corbo
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with few available therapeutic options. Two transcriptional cancer cell states have been consistently reported in PDAC, with the basal-like/squamous phenotype displaying a more aggressive bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6039dd8c6af07f1f4302630d17bce71b
https://doi.org/10.1101/2023.02.25.529923
https://doi.org/10.1101/2023.02.25.529923
Autor:
Oihane Erice, Shruthi Narayanan, Iker Feliu, Rodrigo Entrialgo-Cadierno, Antonia Malinova, Caterina Vicentini, Elizabeth Guruceaga, Pietro Delfino, Marija Trajkovic-Arsic, Haritz Moreno, Karmele Valencia, Ester Blanco, Irati Macaya, Daniel Öhlund, Purvesh Khatri, Fernando Lecanda, Aldo Scarpa, Jens T. Siveke, Vincenzo Corbo, Mariano Ponz-Sarvise, Silve Vicent
Purpose:The identification of pancreatic ductal adenocarcinoma (PDAC) dysregulated genes may unveil novel molecular targets entering inhibitory strategies. Laminins are emerging as potential targets in PDAC given their role as diagnostic and prognost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa5bbf4b2339f0fdd552b0e61962e95
https://hdl.handle.net/11562/1082055
https://hdl.handle.net/11562/1082055
Autor:
Edward T Davis, Michael G. Tomlinson, Lisa Seipold, Murat Keles, Natalie S. Poulter, Paul Saftig, Antonia Malinova, Stephan A. Mueller, Stefan F. Lichtenthaler, Alexandra L. Matthews, Bethany Cragoe, Hanh T.H. Nguyen, Stephen J. Briddon, Nicholas D. Holliday, Christos Pliotas, Chek Ziu Koo, Eric Rubinstein, Thomas A. McFarlane, Johanna Tüshaus, Michael C. Sykes, Justyna Szyroka, Eleanor Cull, Katie Willis, Haroon Ahmed, Alessandro Di Maio, Clara Apicella, Joelle Goulding, Peter J. Noy, Neale Harrison, Hung-En Hsia, Philip R. Morrison
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020, 295 (36), pp.12822-12839. ⟨10.1074/jbc.ra120.012601⟩
The journal of biological chemistry 295(36), 12822-12839 (2020). doi:10.1074/jbc.RA120.012601
J Biol Chem
Journal of Biological Chemistry, 2020, 295 (36), pp.12822-12839. ⟨10.1074/jbc.ra120.012601⟩
Koo, C Z, Harrison, N, Noy, P J, Szyroka, J, Matthews, A L, Hsia, H-E, Müller, S A, Tüshaus, J, Goulding, J, Willis, K, Apicella, C, Cragoe, B, Davis, E, Keles, M, Malinova, A, McFarlane, T A, Morrison, P R, Nguyen, H T H, Sykes, M C, Ahmed, H, Maio, A D, Seipold, L, Saftig, P, Cull, E, Pliotas, C, Rubinstein, E, Poulter, N S, Briddon, S J, Holliday, N D, Lichtenthaler, S F & Tomlinson, M G 2020, ' The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex ', Journal of Biological Chemistry, vol. 295, no. 36, pp. 12822-12839 . https://doi.org/10.1074/jbc.RA120.012601
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020, 295 (36), pp.12822-12839. ⟨10.1074/jbc.ra120.012601⟩
The journal of biological chemistry 295(36), 12822-12839 (2020). doi:10.1074/jbc.RA120.012601
J Biol Chem
Journal of Biological Chemistry, 2020, 295 (36), pp.12822-12839. ⟨10.1074/jbc.ra120.012601⟩
Koo, C Z, Harrison, N, Noy, P J, Szyroka, J, Matthews, A L, Hsia, H-E, Müller, S A, Tüshaus, J, Goulding, J, Willis, K, Apicella, C, Cragoe, B, Davis, E, Keles, M, Malinova, A, McFarlane, T A, Morrison, P R, Nguyen, H T H, Sykes, M C, Ahmed, H, Maio, A D, Seipold, L, Saftig, P, Cull, E, Pliotas, C, Rubinstein, E, Poulter, N S, Briddon, S J, Holliday, N D, Lichtenthaler, S F & Tomlinson, M G 2020, ' The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex ', Journal of Biological Chemistry, vol. 295, no. 36, pp. 12822-12839 . https://doi.org/10.1074/jbc.RA120.012601
International audience; A disintegrin and metalloprotease 10 (ADAM10) is a transmembrane protein essential for embryonic development, and its dysregulation underlies disorders such as cancer, Alzheimer's disease, and inflammation. ADAM10 is a “mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8eb363ab27157e6e501561ef205a029
https://hal.sorbonne-universite.fr/hal-03124330
https://hal.sorbonne-universite.fr/hal-03124330
Autor:
Alexandra L. Matthews, Stefan F. Lichtenthaler, Edward T Davis, Hung-En Hsia, Antonia Malinova, Alessandro Di Maio, Michael G. Tomlinson, Justyna Szyroka, Paul Saftig, Michael C. Sykes, Neale Harrison, Katie Willis, Philip R. Morrison, Eleanor Cull, Chek Ziu Koo, Eric Rubinstein, Clara Apicella, Joelle Goulding, Stephen J. Briddon, Murat Keles, Lisa Seipold, Nicholas D. Holliday, Stephan A. Mueller, Bethany Cragoe, Natalie S. Poulter, Thomas A. McFarlane, Haroon Ahmed, Peter J. Noy, Johanna Tüshaus
A disintegrin and metalloprotease 10 (ADAM10) is essential for embryonic development and impacts on diseases such as cancer, Alzheimer’s and inflammatory diseases. ADAM10 is a ‘molecular scissor’ that proteolytically cleaves the extracellular r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a6ba7b78aec233816b3516d596bd571
https://doi.org/10.1101/800557
https://doi.org/10.1101/800557
Autor:
Lupo, Francesca, Pezzini, Francesco, Pasini, Davide, Fiorini, Elena, Adamo, Annalisa, Veghini, Lisa, Bevere, Michele, Frusteri, Cristina, Delfino, Pietro, D’agosto, Sabrina, Andreani, Silvia, Piro, Geny, Malinova, Antonia, Wang, Tian, De Sanctis, Francesco, Lawlor, Rita Teresa, Hwang, Chang-il, Carbone, Carmine, Amelio, Ivano, Bailey, Peter
Publikováno v:
Gut; Aug2024, Vol. 73 Issue 8, p1321-1335, 43p