Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Antonia M. Fernández-Peralta"'
Publikováno v:
EBioMedicine, Vol 2, Iss 2, p 104 (2015)
Externí odkaz:
https://doaj.org/article/94dd873b1a904338be7e65f3a2ae627f
Autor:
Antonio Martínez-Riera, Alberto Bravo-Gutiérrez, Hugo Álvarez-Argüelles, Vicente Medina-Arana, Antonia M. Fernández-Peralta, Luciano Delgado-Plasencia, Diana Rodríguez-González, Eduardo Salido, Antonio Alarcó-Hernández, Juan J. González-Aguilera
Publikováno v:
Journal of Surgical Oncology. 108:176-181
Aims Recently it has been hypothesized that perforation of colorectal cancer (CRC) itself is not a predictor of poor prognosis. The aim of this study was to analyze the prognostic impact, of the spontaneous perforation of the tumour, metastatic lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bebff7f4aa46aeefcf10a300c6b2fd6d
https://doi.org/10.1002/jso.23373
https://doi.org/10.1002/jso.23373
Autor:
Alberto Bravo-Gutiérrez, D León-Ayllón, Luciano Delgado-Plasencia, Aida Cristina Rahy-Martín, Antonia M. Fernández-Peralta, Vicente Medina-Arana, Antonio Martínez-Riera, D Rodríguez-Castellano, Juan J. González-Aguilera
Publikováno v:
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 18(11)
Very few studies have compared the epidemiological characteristics of patients with familial colorectal cancer Type X (FCCTX) with those of sporadic colorectal cancer (S-CRC). The aim of this study was to compare clinicopathological characteristics a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097ff951065e1683ec157302752e5d46
https://pubmed.ncbi.nlm.nih.gov/27671100
https://pubmed.ncbi.nlm.nih.gov/27671100
Autor:
Antonia M. Fernández-Peralta, Alberto Bravo, Juan J. González-Aguilera, Juana Martín, Vicente Medina-Arana, Luciano Delgado
Publikováno v:
Journal of Surgical Oncology. 106:10-16
Inactivation of Mismatch Repair genes in Lynch Syndrome, caused by inherited mutations, decreases the ability to repair DNA errors throughout life. This deficit may allow the development of any tumor type. Nevertheless, the Syndrome develops a specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699763b3aadeba33f8be56422b5ac542
https://doi.org/10.1002/jso.23054
https://doi.org/10.1002/jso.23054
Autor:
Vicente Medina-Arana, Alberto Bravo, H. Díaz, Juan J. González-Aguilera, Antonia M. Fernández-Peralta, Eduardo Salido, L. González, Débora Riverol, Luciano Delgado
Publikováno v:
Familial Cancer. 10:265-271
Lynch syndrome (LS) is an autosomal dominant condition that predisposes to colorectal cancer and specific other tumors. Extracolonic tumors occur mainly in the endometrium, stomach, ovary, small intestine and urinary tract. The presence of rare tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a759ad26039308957274bc534c5abe
https://doi.org/10.1007/s10689-010-9416-8
https://doi.org/10.1007/s10689-010-9416-8
Autor:
Vicente Medina Arana, Antonia M. Fernández-Peralta, Daniel Iglesias, Juan J. González-Aguilera, Mariano Moreno Azcoita, Nargisse Nejda
Publikováno v:
Cancer Genetics and Cytogenetics. 193:71-77
Germline mutations or the malfunctioning of postreplicative mismatch repair genes (MMR) are responsible of hereditary nonpolyposis colorectal cancer (HNPCC), and are also implied in some sporadic colorectal cancer (CRC) forms without any familial his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fec0643c2d2d01de2264e03b27665c8
https://doi.org/10.1016/j.cancergencyto.2009.04.011
https://doi.org/10.1016/j.cancergencyto.2009.04.011
Autor:
Juan J. González-Aguilera, Eduardo Salido-Ruiz, Antonia M. Fernández-Peralta, Antonio Alarcó-Hernández, Hugo Álvarez-Argüelles, M. Elisa Castro-Peraza, Vicente Medina-Arana, Alberto Bravo-Gutiérrez, Luciano Delgado-Plasencia
Publikováno v:
Pathology, research and practice. 211(12)
Methylenetetrahydrofolate reductase (MTHFR) plays a key role in folate metabolism, and folate is implicated in carcinogenesis due to its role in DNA methylation, repair and synthesis. The MTHFR C677T polymorphism is associated with decreased risk of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cfdcf3a5f5544b3510b365432c0f7e3
https://pubmed.ncbi.nlm.nih.gov/26564107
https://pubmed.ncbi.nlm.nih.gov/26564107
Publikováno v:
EBioMedicine, Vol 2, Iss 2, p 104 (2015)
EBioMedicine
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
EBioMedicine
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Background Clinical assessment and prognostic stratification of primary varicose veins have remained controversial and the molecular pathogenesis is unknown. Previous data have suggested a contribution of the MTHFR (methylenetetrahydrofolate reductas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93bf138b20b012d8b52fd2618d8db932
http://www.sciencedirect.com/science/article/pii/S2352396415000407
http://www.sciencedirect.com/science/article/pii/S2352396415000407
Autor:
Carlos Cerquella, Soledad Oliart, Lydia Daimiel, Mariano Moreno-Azcoita, Daniel Iglesias, Juan J. González-Aguilera, Nargisse Nejda, Cristina Martinez-Santos, Antonia M. Fernández-Peralta
Publikováno v:
American Journal of Clinical Oncology. 29:364-370
Background: The mutator pathway implied in the development of colorectal cancer (CRC) is characterized by microsatellite instability (MSI). MSI tumors can be subdivided according to the level of instability: MSI-H (high), MSI-L (low) or stable MSS. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5074dfa27ee669b727d3b16509b4860b
https://doi.org/10.1097/01.coc.0000221428.35366.cb
https://doi.org/10.1097/01.coc.0000221428.35366.cb
Autor:
Soledad Oliart, Juan J. González-Aguilera, Antonia M. Fernández-Peralta, Lidia Daimiel, Nargisse Nejda, Mariano Moreno Azcoita, Daniel Iglesias
Publikováno v:
Cancer Genetics and Cytogenetics. 167:138-144
Microsatellite instability (MSI) due to mismatch repair system (MMR) alterations characterizes the mutator pathway implied in colorectal cancer development. In the present study, we have analyzed the gene RIS1 (Ras-induced senescence 1) in relation t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8bbd8a26c387afd90424e0bdade9c51
https://doi.org/10.1016/j.cancergencyto.2005.12.002
https://doi.org/10.1016/j.cancergencyto.2005.12.002