Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Antonia M Davidson"'
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 381(1)
CVN424 is a novel small molecule and first-in-class candidate therapeutic to selectively modulate GPR6, an orphan G-protein coupled receptor. Expression of GPR6 is largely confined to the subset of striatal projection neurons that give rise to the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b715384157c158490578340a3b61b97
https://pubmed.ncbi.nlm.nih.gov/35110393
https://pubmed.ncbi.nlm.nih.gov/35110393
Autor:
Joyce Zhan, Max Lataillade, Sherene Min, Mark Johnson, Lindsey Webster, Samit R Joshi, Laurie Butcher, Eric Zimmerman, Teodora Pene Dumitrescu, Jianfeng Xu, Antonia M Davidson
Publikováno v:
Antimicrobial Agents and Chemotherapy
GSK3640254 is a next-generation maturation inhibitor that would likely be combined with standard antiretroviral agents to form a regimen of ≥2 fully active classes. This phase I, open-label, 2-period, 1-way study assessed potential pharmacokinetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234aa50c6fdff7ae43b0c1cba1e9eb50
https://doi.org/10.1128/aac.02173-20
https://doi.org/10.1128/aac.02173-20
Autor:
Anne Gardin, Felix Huth, Antonia M Davidson, Eric Legangneux, Kasra Shakeri-Nejad, Cathy Gray, Swati Dumitras, Srikanth Neelakantham
Publikováno v:
European Journal of Clinical Pharmacology. 74:1593-1604
To assess the potential pharmacokinetic (PK) interactions between siponimod and rifampin, a strong CYP3A4/moderate CYP2C9 inducer, in healthy subjects. This was a confirmatory, open-label, multiple-dose two-period study in healthy subjects (aged 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0b6929bedb3f3a49b7da486da9afd4
https://doi.org/10.1007/s00228-018-2533-2
https://doi.org/10.1007/s00228-018-2533-2