Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Antonia Kefala Stavridi"'
Autor:
Shikang Liang, Tom L. Blundell, Amanda K. Chaplin, Aleš Hnízda, Antonia Kefala Stavridi, Robert Appleby
Publikováno v:
Progress in Biophysics and Molecular Biology
Non-homologous end joining (NHEJ) is the preferred pathway for the repair of DNA double-strand breaks in humans. Here we describe three structural aspects of the repair pathway: stages, scaffolds and strings. We discuss the orchestration of DNA repai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca43e6e448ffae277c09ed2c9f19bd34
https://www.repository.cam.ac.uk/handle/1810/316479
https://www.repository.cam.ac.uk/handle/1810/316479
Autor:
Antonia Kefala Stavridi, Virginie Ropars, Shikang Liang, Amanda K. Chaplin, Jean-Baptiste Charbonnier, Dimitri Y. Chirgadze, Steven W. Hardwick, Noah J Goff, Tom L. Blundell, Taiana Maia de Oliveira, Katheryn Meek, Christopher J. Buehl
Non-homologous end joining (NHEJ) is one of two critical mechanisms utilized in humans to repair DNA double-strand breaks (DSBs). Unrepaired or incorrect repair of DSBs can lead to apoptosis or cancer. NHEJ involves several proteins, including the Ku
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff291ec26fc79784cdf65b31e9d37f60
Publikováno v:
Essays in Biochemistry
Non-homologous end joining (NHEJ) is one of the two principal damage repair pathways for DNA double-strand breaks in cells. In this review, we give a brief overview of the system including a discussion of the effects of deregulation of NHEJ component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2742056c52362d3481a470e01d449884
Autor:
Taiana Maia de Oliveira, Lee R Cooper, Antonia Kefala Stavridi, Amanda K. Chaplin, Tom L. Blundell, Shikang Liang, Aleš Hnízda, Dimitri Y. Chirgadze, Steven W. Hardwick
DNA double-strand breaks are the most dangerous type of DNA damage and, if not repaired correctly, can lead to cancer. In humans, Ku70/80 recognizes DNA broken ends and recruits the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) to form DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f304c752084a53735a663b170fd4ef
https://www.repository.cam.ac.uk/handle/1810/309624
https://www.repository.cam.ac.uk/handle/1810/309624
Autor:
Amanda K, Chaplin, Steven W, Hardwick, Shikang, Liang, Antonia, Kefala Stavridi, Ales, Hnizda, Lee R, Cooper, Taiana Maia, De Oliveira, Dimitri Y, Chirgadze, Tom L, Blundell
Publikováno v:
Nature structuralmolecular biology. 28(1)
DNA double-strand breaks are the most dangerous type of DNA damage and, if not repaired correctly, can lead to cancer. In humans, Ku70/80 recognizes DNA broken ends and recruits the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) to form DN
Autor:
Murielle Seif-El-Dahan, Antonia Kefala-Stavridi, Philippe Frit, Steven W. Hardwick, Dima Y. Chirgadze, Taiana Maia De Oliviera, Sébastien Britton, Nadia Barboule, Madeleine Bossaert, Arun Prasad Pandurangan, Katheryn Meek, Tom L. Blundell, Virginie Ropars, Patrick Calsou, Jean-Baptiste Charbonnier, Amanda K. Chaplin
Publikováno v:
Science Advances. 9(22)
Nonhomologous end joining is a critical mechanism that repairs DNA double-strand breaks in human cells. In this work, we address the structural and functional role of the accessory protein PAXX [paralog of x-ray repair cross-complementing protein 4 (