Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Antonia García-Garzón"'
Autor:
Antonia García-Garzón, Marta M. Alonso, Enric Xipell, Juan Jose Martinez de Irujo, Candelaria Gomez-Manzano, F. Lang, Marisol Gonzalez-Huarriz, Hong Jiang, Juan Fueyo
Publikováno v:
Oncotarget
Glioblastoma is the most frequent malignant brain tumor. Even with aggressive treatment, prognosis for patients is poor. One characteristic of glioblastoma cells is its intrinsic resistance to apoptosis. Therefore, drugs that induce alternative cell
Autor:
Enric Xipell, Tomás J. Aragón, Miguel Angel Idoate, Antonia García Garzón, Marta M. Alonso, Naiara Martinez-Velez, Frederick F. Lang, Beatriz Vera, Juan J. Martinez-Irujo, Marisol Gonzalez-Huarriz, Arlet M. Acanda, Juan Fueyo, Chris Jones, Candelaria Gomez-Manzano
Publikováno v:
Neuro-Oncology. 18:1109-1119
Background Endoplasmic reticulum (ER) stress results from protein misfolding imbalance and has been postulated as a therapeutic strategy. ER stress activates the unfolded protein response which leads to a complex cellular response, including the upre
Autor:
Eduardo Ansorena, María J. Iraburu, María J. López-Zabalza, Guillermo Zalba, Antonia García-Garzón, Naiara Garde, Aitor Andueza, Juan J. Martinez-Irujo
Publikováno v:
Free radical biologymedicine. 126
NADPH oxidase (Nox) variants Nox1, Nox2 and Nox4 are implicated in the progression of liver fibrosis. However, the role of Nox5 is not yet known, mainly due to the lack of this enzyme in rat and mouse genomes. Here we describe the expression and func
Autor:
Teresa Mòdol, Antonia García Garzón, María J. López-Zabalza, Juan J. Martinez-Irujo, María J. Iraburu, Natalia Brice, Marina Ruiz de Galarreta
Publikováno v:
Journal of Cellular Physiology. 230:546-553
The turnover of extracellular matrix (ECM) components can generate signals that regulate several cellular functions such as proliferation, differentiation, and apoptosis. During liver injury, matrix metalloproteases (MMPs) production is enhanced and
Autor:
Aitor Andueza, Eduardo Ansorena, María J. López-Zabalza, Antonia García-Garzón, María J. Iraburu, Guillermo Zalba, Naiara Garde, Juan J. Martinez-Irujo
Publikováno v:
Free Radical Biology and Medicine. 120:S86
NADPH oxidase (Nox) variants Nox1, Nox2 and Nox4 have been implicated in the progression of liver fibrosis. However, the role of Nox5 is unknown, mainly due to the lack of this enzyme in rat and mouse genomes. Here we describe the expression and func
Autor:
Teresa Mòdol, María J. López-Zabalza, Eduardo Ansorena, María J. Iraburu, Juan J. Martinez-Irujo, Amaia Navarro, Marina Ruiz de Galarreta, Antonia García Garzón
Publikováno v:
Biochimica et biophysica acta. 1863(8)
Unfolded protein response (UPR) triggered as a consequence of ER stress has been shown to be involved in the development of different pathologies, including fibrotic disorders. In the present paper we explore the role played by UPR on a key fibrogeni
Autor:
Marina Ruiz de Galarreta, María J. López-Zabalza, Juan J. Martinez-Irujo, Aitor Andueza, Eduardo Ansorena, María J. Iraburu, Antonia García-Garzón
Publikováno v:
Free radical biologymedicine. 87
Apigenin, a natural flavone, is emerging as a promising compound for the treatment of several diseases. One of the hallmarks of apigenin is the generation of intracellular reactive oxygen species (ROS), as judged by the oxidation of reduced dichlorof
Autor:
Teresa, Mòdol, Natalia, Brice, Marina, Ruiz de Galarreta, Antonia, García Garzón, María J, Iraburu, Juan J, Martínez-Irujo, María J, López-Zabalza
Publikováno v:
Journal of cellular physiology. 230(3)
The turnover of extracellular matrix (ECM) components can generate signals that regulate several cellular functions such as proliferation, differentiation, and apoptosis. During liver injury, matrix metalloproteases (MMPs) production is enhanced and
Autor:
Enric Xipell, Candelaria Gomez-Manzano, Marta M. Alonso, Arlet M. Acanda, Naiara Martinez-Velez, Juan Fueyo, Miguel Angel Idoate, Antonia García Garzón, Beatriz Vera-Cano
Publikováno v:
Neuro-Oncology. 16:v93-v93
Termozolamide (TMZ) is the standard treatment against GBM, unfortunately its therapeutic effect is limited due to the expression of the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT). Therefore, approaches that overcome the resistan