Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Antonia Donat"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 2869-2884 (2024)
The worldwide burden of skeletal diseases such as osteoporosis, degenerative joint disease and impaired fracture healing is steadily increasing. Tranexamic acid (TXA), a plasminogen inhibitor and anti-fibrinolytic agent, is used to reduce bleeding wi
Externí odkaz:
https://doaj.org/article/292e26dc25024d678886378fa30a29c7
Autor:
Shan Jiang, Weixin Xie, Paul Richard Knapstein, Antonia Donat, Lilly-Charlotte Albertsen, Jan Sevecke, Cordula Erdmann, Jessika Appelt, Melanie Fuchs, Alexander Hildebrandt, Tazio Maleitzke, Karl-Heinz Frosch, Anke Baranowsky, Johannes Keller
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Osteoarthritis represents a chronic degenerative joint disease with exceptional clinical relevance. Polymorphisms of the CALCA gene, giving rise to either a procalcitonin/calcitonin (PCT/CT) or a calcitonin gene-related peptide alpha (αCGRP
Externí odkaz:
https://doaj.org/article/a90dc4abb1f74a018b4b750f27567b9c
Autor:
Antonia Donat, Shan Jiang, Weixin Xie, Paul Richard Knapstein, Lilly-Charlotte Albertsen, Judith Luisa Kokot, Jan Sevecke, Ruben Augustin, Denise Jahn, Timur Alexander Yorgan, Karl-Heinz Frosch, Serafeim Tsitsilonis, Anke Baranowsky, Johannes Keller
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107761- (2023)
Summary: Impaired fracture healing is of high clinical relevance, as up to 15% of patients with long-bone fractures display non-unions. Fracture patients also include individuals treated with selective norepinephrine reuptake inhibitors (SNRI). As SN
Externí odkaz:
https://doaj.org/article/3a945e1785104d0bb97697744e0f6340
Autor:
Justus M. Grewe, Paul-Richard Knapstein, Antonia Donat, Shan Jiang, Daniel J. Smit, Weixin Xie, Johannes Keller
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-9 (2022)
Abstract Osteoporosis is a systemic bone disease that affects more than 200 million people worldwide and is caused by the disruption of the equilibrium between osteoclastic bone resorption and osteoblastic bone formation. Sphingosine-1-phosphate (S1P
Externí odkaz:
https://doaj.org/article/d3786b0f0fc74921b23a5584f647c5a2
Autor:
Anke Baranowsky, Denise Jahn, Shan Jiang, Timur Yorgan, Peter Ludewig, Jessika Appelt, Kai K. Albrecht, Ellen Otto, Paul Knapstein, Antonia Donat, Jack Winneberger, Lana Rosenthal, Paul Köhli, Cordula Erdmann, Melanie Fuchs, Karl-Heinz Frosch, Serafeim Tsitsilonis, Michael Amling, Thorsten Schinke, Johannes Keller
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Intermittent injections of parathyroid hormone (iPTH) are applied clinically to stimulate bone formation by osteoblasts, although continuous elevation of parathyroid hormone (PTH) primarily results in increased bone resorption. Here, we iden
Externí odkaz:
https://doaj.org/article/ac9d33378f734b29bdcaf0cf65de4ddc
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100798- (2021)
Summary: Fracture healing represents a dynamic and complex process which depends on the balanced activities of a broad array of different cell types and signaling pathways. Here, we describe a femoral osteotomy protocol for mice, using an external fi
Externí odkaz:
https://doaj.org/article/91bc4879a5414243a9e1ed190112c514
Publikováno v:
Biomarkers in Trauma, Injury and Critical Care ISBN: 9783031073946
Biomarkers in Trauma, Injury and Critical Care ISBN: 9783030873028
Biomarkers in Trauma, Injury and Critical Care ISBN: 9783030873028
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f1ba8fb295e89276a17728704a82b1
https://doi.org/10.1007/978-3-031-07395-3_31
https://doi.org/10.1007/978-3-031-07395-3_31
Autor:
David A.C. Messerer, Thomas Datzmann, Anke Baranowsky, Leandra Peschel, Andrea Hoffmann, Michael Gröger, Michael Amling, Martin Wepler, Benedikt L. Nussbaum, Shan Jiang, Paul Knapstein, Antonia Donat, Enrico Calzia, Peter Radermacher, Johannes Keller
Publikováno v:
British journal of anaesthesia. 128(5)
Calcitonin gene-related peptide (CGRP) and procalcitonin, which are overexpressed in sepsis, exert distinct immunomodulatory effects mediated through the CGRP receptor. The CGRP receptor antagonist olcegepant improves survival in murine sepsis. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7b351c7083bcbaf1a9658d8291b8bf
https://pubmed.ncbi.nlm.nih.gov/35131096
https://pubmed.ncbi.nlm.nih.gov/35131096
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100798-(2021)
STAR Protocols
STAR Protocols
Summary Fracture healing represents a dynamic and complex process which depends on the balanced activities of a broad array of different cell types and signaling pathways. Here, we describe a femoral osteotomy protocol for mice, using an external fix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777361d37b1f44299a0e640690012f5a
http://www.sciencedirect.com/science/article/pii/S2666166721005049
http://www.sciencedirect.com/science/article/pii/S2666166721005049
Autor:
Justus M. Grewe, Paul-Richard Knapstein, Antonia Donat, Shan Jiang, Daniel J. Smit, Weixin Xie, Johannes Keller
Publikováno v:
Bone research. 10(1)
Osteoporosis is a systemic bone disease that affects more than 200 million people worldwide and is caused by the disruption of the equilibrium between osteoclastic bone resorption and osteoblastic bone formation. Sphingosine-1-phosphate (S1P) is a na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b4b556b2886a809b984bc2b48ec1cf
https://pubmed.ncbi.nlm.nih.gov/35396384
https://pubmed.ncbi.nlm.nih.gov/35396384