Molecular Aspects of Spike–ACE2 Interaction

Autor: Luigi De Masi, Maria Antonia Argenio, Deborah Giordano, Angelo Facchiano

Publikováno v: Encyclopedia, Vol 2, Iss 1, Pp 96-108 (2022)

A new betacoronavirus (CoV-2) is responsible for the pandemic of severe acute respiratory syndrome (SARS) that began in China at the end of 2019, today known as COronaVIrus Disease 2019 (COVID-19). Subsequent studies confirmed the human angiotensin-c

Externí odkaz: https://doaj.org/article/cac862ab9c6a41b6826bfce31c03bd04

Investigating the Effects of Amino Acid Variations in Human Menin

Autor: Carmen Biancaniello, Antonia D’Argenio, Deborah Giordano, Serena Dotolo, Bernardina Scafuri, Anna Marabotti, Antonio d’Acierno, Roberto Tagliaferri, Angelo Facchiano

Publikováno v: Molecules, Vol 27, Iss 5, p 1747 (2022)

Human menin is a nuclear protein that participates in many cellular processes, as transcriptional regulation, DNA damage repair, cell signaling, cell division, proliferation, and migration, by interacting with many other proteins. Mutations of the ge

Externí odkaz: https://doaj.org/article/f1d231b308c54b6094a90bb1e347c12e

Molecular dissection of the inter-chain interface of the human Angiotensin-Converting Enzyme 2 (ACE2) receptor with the SARS-CoV-2 Spike-protein

Autor: Deborah Giordano (1), Maria Antonia Argenio (1), Luigi De Masi (2), Angelo Facchiano (1)

Publikováno v: BITS 2021-The 17th Annual Meeting of the Bioinformatics Italian Society, pp. 65–65, online, 1-2/07/2021
info:cnr-pdr/source/autori:Deborah Giordano (1); Maria Antonia Argenio (1); Luigi De Masi (2); Angelo Facchiano (1)/congresso_nome:BITS 2021-The 17th Annual Meeting of the Bioinformatics Italian Society/congresso_luogo:online/congresso_data:1-2%2F07%2F2021/anno:2021/pagina_da:65/pagina_a:65/intervallo_pagine:65–65

Motivation The COVID-19 pandemic has prompted many researchers to deepen knowledge of the interaction mechanisms that allow the coronavirus attack to the human target cells. It is well recognized that human ACE2 acts as a cellular receptor of the Spi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::15488b0102530e93a2b4397b6fa07a2d
https://publications.cnr.it/doc/459794

Structural Dissection of Viral Spike-Protein Binding of SARS-CoV-2 and SARS-CoV-1 to the Human Angiotensin-Converting Enzyme 2 (ACE2) as Cellular Receptor

Autor: Angelo Facchiano, Deborah Giordano, Luigi De Masi, Maria Antonia Argenio

Publikováno v: Biomedicines, Vol 9, Iss 1038, p 1038 (2021)
Biomedicines 9 (2021). doi:10.3390/biomedicines9081038
info:cnr-pdr/source/autori:Deborah Giordano, Luigi De Masi, Maria Antonia Argenio, and Angelo Facchiano/titolo:Structural Dissection of Viral Spike-Protein Binding of SARS-CoV-2 and SARS-CoV-1 to the Human Angiotensin-Converting Enzyme 2 (ACE2) as Cellular Receptor/doi:10.3390%2Fbiomedicines9081038/rivista:Biomedicines/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Biomedicines
Volume 9
Issue 8

An outbreak by a new severe acute respiratory syndrome betacoronavirus (SARS-CoV-2) has spread CoronaVirus Disease 2019 (COVID-19) all over the world. Immediately, following studies have confirmed the human Angiotensin-Converting Enzyme 2 (ACE2) as a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66922839521fdfa0b7d05d94b16374b9
https://doi.org/10.3390/biomedicines9081038

Investigating the Effects of Amino Acid Variations in Human Menin.

Autor: Biancaniello, Carmen¹ (AUTHOR) carmenbnl93@gmail.com, D’Argenio, Antonia² (AUTHOR) antoniadargenio1@gmail.com, Giordano, Deborah² (AUTHOR) deborah.giordano@isa.cnr.it, Dotolo, Serena¹ (AUTHOR) sdotolo@unisa.it, Scafuri, Bernardina³ (AUTHOR) bscafuri@unisa.it, Marabotti, Anna³ (AUTHOR) amarabotti@unisa.it, d’Acierno, Antonio² (AUTHOR) dacierno.a@isa.cnr.it, Tagliaferri, Roberto¹ (AUTHOR) robtag@unisa.it, Facchiano, Angelo² (AUTHOR) angelo.facchiano@isa.cnr.it

Publikováno v: Molecules. Mar2022, Vol. 27 Issue 5, p1-13. 13p. 6 Color Photographs.