Výsledky vyhledávání - "Antonia Brings"

Perpetrator effects of ciclosporin (P‐glycoprotein inhibitor) and its combination with fluconazole (CYP3A inhibitor) on the pharmacokinetics of rivaroxaban in healthy volunteers

Autor: Antonia Brings, David Czock, Marie-Louise Lehmann, Johanna Weiss, Kathrin I. Foerster, Walter E. Haefeli, Jürgen Burhenne

Publikováno v: Br J Clin Pharmacol

Aims Rivaroxaban exposure is considerably increased by drugs that are combined P-glycoprotein (P-gp) and strong cytochrome P450 (CYP) 3A inhibitors (e.g. ketoconazole). The aim of the present study was to investigate the effects of the potent P-gp in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783ea078204f6e5fc775007b44906a4c
https://doi.org/10.1111/bcp.13934

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