Zobrazeno 1 - 10
of 1 803
pro vyhledávání: '"Antoni G"'
Autor:
Teddi Herring, Antoni G. Lewkowicz, Alexandre Chiasson, Yifeng Wang, Robert G. Way, Joseph M. Young, Duane Froese, Sharon L. Smith, Brielle Andersen, Olivier Bellehumeur-Génier, Alexandre R. Bevington, Philip P. Bonnaventure, Maxime A. Duguay, Bernd Etzelmüller, Michael N. Gooseff, Sarah E. Godsey, Christina M. Miceli
Publikováno v:
Arctic Science, Vol 10, Iss 4, Pp 850-856 (2024)
Permafrost landscapes are becoming increasingly susceptible to widespread thaw due to climate change. Collating historical and ongoing data are critical for assessing permafrost conditions and spatiotemporal changes. Electrical resistivity tomography
Externí odkaz:
https://doaj.org/article/3a63ff9ca64a489da47699485f23df4e
Autor:
Lena Jaki, Sebastian Weigang, Lisa Kern, Stefanie Kramme, Antoni G. Wrobel, Andrea B. Grawitz, Philipp Nawrath, Stephen R. Martin, Theo Dähne, Julius Beer, Miriam Disch, Philipp Kolb, Lisa Gutbrod, Sandra Reuter, Klaus Warnatz, Martin Schwemmle, Steven J. Gamblin, Elke Neumann-Haefelin, Daniel Schnepf, Thomas Welte, Georg Kochs, Daniela Huzly, Marcus Panning, Jonas Fuchs
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Monoclonal antibodies (mAbs) directed against the spike of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are effective therapeutic options to combat infections in high-risk patients. Here, we report the adaptation of SARS-CoV-
Externí odkaz:
https://doaj.org/article/d61edc8bae2d4d3c8f29f4fd3b6b89ba
Autor:
Valeria Calvaresi, Antoni G. Wrobel, Joanna Toporowska, Dietmar Hammerschmid, Katie J. Doores, Richard T. Bradshaw, Ricardo B. Parsons, Donald J. Benton, Chloë Roustan, Eamonn Reading, Michael H. Malim, Steve J. Gamblin, Argyris Politis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
In this paper, the authors use hydrogen-deuterium exchange mass spectrometry to describe how the SARS-CoV-2 spike glycoprotein has evolved its structural dynamics features and receptor binding capability from the emergence of the original Wuhan isola
Externí odkaz:
https://doaj.org/article/97f9efb389ef48dfa07633acc7b2d899
Evolutionarily conserved amino acids in MHC-II mediate bat influenza A virus entry into human cells.
Autor:
Okikiola M Olajide, Maria Kaukab Osman, Jonathan Robert, Susanne Kessler, Lina Kathrin Toews, Thiprampai Thamamongood, Jacques Neefjes, Antoni G Wrobel, Martin Schwemmle, Kevin Ciminski, Peter Reuther
Publikováno v:
PLoS Biology, Vol 21, Iss 7, p e3002182 (2023)
The viral hemagglutinins of conventional influenza A viruses (IAVs) bind to sialylated glycans on host cell surfaces for attachment and subsequent infection. In contrast, hemagglutinins of bat-derived IAVs target major histocompatibility complex clas
Externí odkaz:
https://doaj.org/article/8438d075ef604f679beac4bf69d41a3c
Autor:
Antoni G. Wrobel, Donald J. Benton, Chloë Roustan, Annabel Borg, Saira Hussain, Stephen R. Martin, Peter B. Rosenthal, John J. Skehel, Steven J. Gamblin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-7 (2022)
The SARS-CoV-2 spike has been evolving in the human population. The variants of concern alpha and beta evolved to optimise spike openness and so ability to bind its receptor ACE2, the affinity towards the receptor, and stability upon receptor binding
Externí odkaz:
https://doaj.org/article/b4dd4e7327c04cb0a388bbe45794406e
Autor:
Antoni G. Wrobel, Donald J. Benton, Pengqi Xu, Lesley J. Calder, Annabel Borg, Chloë Roustan, Stephen R. Martin, Peter B. Rosenthal, John J. Skehel, Steven J. Gamblin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-6 (2021)
It has been suggested that pangolin coronaviruses may be the origin of SARS-CoV-2. Here the authors show that the Pangolin-CoV spike is structurally closely related to the closed form of SARS-CoV-2 spike and exhibits similar binding properties to hum
Externí odkaz:
https://doaj.org/article/e6fc3e78a8f74f72b0f0a1e0880a8bb4
Autor:
Antoni G. Wrobel, Donald J. Benton, Saira Hussain, Ruth Harvey, Stephen R. Martin, Chloë Roustan, Peter B. Rosenthal, John J. Skehel, Steven J. Gamblin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-5 (2020)
Here, the authors characterise the binding and neutralisation properties of CR3022, a neutralising Ab isolated from a convalescent SARS patient, against SARS-CoV-2 spike trimers and show using Cryo-EM the disruption of SARS-CoV-2 spike by CR3022 Fab.
Externí odkaz:
https://doaj.org/article/d4d4b2a7e1194f45b301bc4c82ffd83f
Autor:
Antoni G. Lewkowicz, Robert G. Way
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Retrogressive thaw slumps (RTS) are landslides caused by melting ground ice in permafrost areas. Based on Google Earth Engine Timelapse data, the authors show an unprecedented 60-fold increase in RTS numbers for Banks Island, Canada, from 1984 to 201
Externí odkaz:
https://doaj.org/article/dc5173efbd7e4353a39c034b7dd6aeee
Autor:
Boris K. Biskaborn, Sharon L. Smith, Jeannette Noetzli, Heidrun Matthes, Gonçalo Vieira, Dmitry A. Streletskiy, Philippe Schoeneich, Vladimir E. Romanovsky, Antoni G. Lewkowicz, Andrey Abramov, Michel Allard, Julia Boike, William L. Cable, Hanne H. Christiansen, Reynald Delaloye, Bernhard Diekmann, Dmitry Drozdov, Bernd Etzelmüller, Guido Grosse, Mauro Guglielmin, Thomas Ingeman-Nielsen, Ketil Isaksen, Mamoru Ishikawa, Margareta Johansson, Halldor Johannsson, Anseok Joo, Dmitry Kaverin, Alexander Kholodov, Pavel Konstantinov, Tim Kröger, Christophe Lambiel, Jean-Pierre Lanckman, Dongliang Luo, Galina Malkova, Ian Meiklejohn, Natalia Moskalenko, Marc Oliva, Marcia Phillips, Miguel Ramos, A. Britta K. Sannel, Dmitrii Sergeev, Cathy Seybold, Pavel Skryabin, Alexander Vasiliev, Qingbai Wu, Kenji Yoshikawa, Mikhail Zheleznyak, Hugues Lantuit
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Climate change strongly impacts regions in high latitudes and altitudes that store high amounts of carbon in yet frozen ground. Here the authors show that the consequence of these changes is global warming of permafrost at depths greater than 10 m in
Externí odkaz:
https://doaj.org/article/735d8e41aac649eebc6089a698a38eec
Autor:
Paul E Chappell, El Kahina Meziane, Michael Harrison, Łukasz Magiera, Clemens Hermann, Laura Mears, Antoni G Wrobel, Charlotte Durant, Lise Lotte Nielsen, Søren Buus, Nicola Ternette, William Mwangi, Colin Butter, Venugopal Nair, Trudy Ahyee, Richard Duggleby, Alejandro Madrigal, Pietro Roversi, Susan M Lea, Jim Kaufman
Publikováno v:
eLife, Vol 4 (2015)
Highly polymorphic major histocompatibility complex (MHC) molecules are at the heart of adaptive immune responses, playing crucial roles in many kinds of disease and in vaccination. We report that breadth of peptide presentation and level of cell sur
Externí odkaz:
https://doaj.org/article/401c28ae24f148d385a2c6b49fd379e2