An introduction to immunology and immunopathology

Autor: Warrington Richard, Watson Wade, Kim Harold L, Antonetti Francesca

Publikováno v: Allergy, Asthma & Clinical Immunology, Vol 7, Iss Suppl 1, p S1 (2011)

Abstract In basic terms, the immune system has two lines of defense: innate immunity and adaptive immunity. Innate immunity is the first immunological, non-specific (antigen-independent) mechanism for fighting against an intruding pathogen. It is a r

Externí odkaz: https://doaj.org/article/d4c32d9c1c1f4bf883c217e515d37483

MicroRNA-155 Targets the SKI Gene in Human Melanoma Cell Lines

Autor: Lauretta, Levati, Elena, Pagani, Sveva, Romani, Daniele, Castiglia, Eugenia, Piccinni, Claudia, Covaciu, Patrizia, Caporaso, Sergio, Bondanza, Francesca R, Antonetti, Enzo, Bonmassar, Fabio, Martelli, Ester, Alvino, Stefania, D'Atri

Publikováno v: Pigment cell & melanoma research
(2011).
info:cnr-pdr/source/autori:Lauretta Levati, Elena Pagani, Sveva Romani, Daniele Castiglia, Eugenia Piccinni, Claudia Covaciu, Patrizia Caporaso, Sergio Bondanza, Francesca Romana Antonetti, Enzo Bonmassar, Fabio Martelli, Ester Alvino and Stefania D’Atri/titolo:MicroRNA-155 Targets the SKI Gene in Human Melanoma Cell Lines/doi:/rivista:Pigment cell & melanoma research (Print)/anno:2011/pagina_da:/pagina_a:/intervallo_pagine:/volume
24 (2011): 538–550. doi:10.1111/j.1755-148X.2011.00857.x
info:cnr-pdr/source/autori:Levati, Lauretta; Pagani, Elena; Romani, Sveva; Castiglia, Daniele; Piccinni, Eugenia; Covaciu, Claudia; Caporaso, Patrizia; Bondanza, Sergio; Antonetti, Francesca R.; Bonmassar, Enzo; Martelli, Fabio; Alvino, Ester; D'Atri, Stefania/titolo:MicroRNA-155 targets the SKI gene in human melanoma cell lines/doi:10.1111%2Fj.1755-148X.2011.00857.x/rivista:Pigment cell & melanoma research (Print)/anno:2011/pagina_da:538/pagina_a:550/intervallo_pagine:538–550/volume:24

P>The SKI protein is a transcriptional coregulator over-expressed in melanoma. Experimentally induced down-regulation of SKI inhibits melanoma cell growth in vitro and in vivo. MicroRNAs (miRNAs) negatively modulate gene expression and have been impl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4e80a57123bb317f3af9ff12aa93b5d5
https://publications.cnr.it/doc/59190