Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Antonello di Paolo"'
Autor:
Sara Galimberti, Elisabetta Abruzzese, Giacomo Luci, Claudia Baratè, Luigia Luciano, Alessandra Iurlo, Giovanni Caocci, Riccardo Morganti, Fabio Stefanelli, Antonello Di Paolo
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 383 (2024)
Ponatinib may be effective in chronic myeloid leukemia (CML) patients after failure of first/second line therapies. Although its efficacy for minimum plasma concentrations (Cmin) is >21.3 ng/mL (equal to 40 nM), ponatinib may cause adverse events (AE
Externí odkaz:
https://doaj.org/article/905600479e6940c5ac0e2637b4d51945
Autor:
Giovanni Fulvio, Chiara Baldini, Marta Mosca, Antonello di Paolo, Guido Bocci, Giuseppe Alberto Palumbo, Emma Cacciola, Paola Migliorini, Rossella Cacciola, Sara Galimberti
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
In this article, we reviewed the possible mechanisms linking the clonal hematopoiesis of indeterminate potential (CHIP) to chronic myeloproliferative neoplasms (MPNs), autoimmune diseases (ADs), and cardiovascular diseases (CADs). CHIP is characteriz
Externí odkaz:
https://doaj.org/article/c74c4682f9b84b2ca560a46b7004c88c
Autor:
Natalia Maximova, Daniela Nistico’, Annalisa Marcuzzi, Erika Rimondi, Antimo Tessitore, Guglielmo Riccio, Egidio Barbi, Antonello DI Paolo
Publikováno v:
HemaSphere, Vol 7, p e7327865 (2023)
Externí odkaz:
https://doaj.org/article/ffde59c527d846fd89b972beebf06ad4
Autor:
Letizia Biso, Marco Carli, Shivakumar Kolachalam, Giorgio Monticelli, Pasquale Fabio Calabrò, Antonello di Paolo, Filippo Sean Giorgi, Guido Bocci, Marco Scarselli
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 945 (2023)
Despite receiving appropriate antiseizure medications (ASMs), a relevant percentage of neuropsychiatric patients do not benefit from this approach, and one reason is subtherapeutic ASMs plasma concentration (C(p)) due to improper drug adherence, inte
Externí odkaz:
https://doaj.org/article/938c3c880f484e77965fab7cb07d53fa
Autor:
Federico Cucchiara, Giacomo Luci, Noemi Giannini, Filippo Sean Giorgi, Paola Orlandi, Marta Banchi, Antonello Di Paolo, Francesco Pasqualetti, Romano Danesi, Guido Bocci
Publikováno v:
Pharmacological Research, Vol 181, Iss , Pp 106290- (2022)
Glioblastoma multiforme (GBM) is an aggressive brain tumor, often occurring with seizures managed with antiepileptic drugs, such as levetiracetam (LEV). This study is aimed at associating progression-free survival (PFS) and overall survival (OS) of G
Externí odkaz:
https://doaj.org/article/53635defdfb448509408cfa093585276
Autor:
Natalia Maximova, Daniela Nisticò, Giacomo Luci, Roberto Simeone, Elisa Piscianz, Ludovica Segat, Egidio Barbi, Antonello Di Paolo
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Acyclovir represents the first-line prophylaxis and therapy for herpes virus infections. However, its pharmacokinetics in children exposes them to the risk of ineffective or toxic concentrations. The study was aimed at investigating the p
Externí odkaz:
https://doaj.org/article/b70f40f7dfe44a40aa3aceeaf2d00544
Autor:
Bruno Viaggi, Alice Cangialosi, Martin Langer, Carlo Olivieri, Andrea Gori, Alberto Corona, Stefano Finazzi, Antonello Di Paolo
Publikováno v:
Antibiotics, Vol 11, Iss 9, p 1193 (2022)
In patients that are admitted to intensive care units (ICUs), the clinical outcome of severe infections depends on several factors, as well as the early administration of chemotherapies and comorbidities. Antimicrobials may be used in off-label regim
Externí odkaz:
https://doaj.org/article/efba513de3a24548bb097b8410b1b4ed
Autor:
Stefano Finazzi, Giacomo Luci, Carlo Olivieri, Martin Langer, Giulia Mandelli, Alberto Corona, Bruno Viaggi, Antonello Di Paolo
Publikováno v:
Antibiotics, Vol 11, Iss 9, p 1164 (2022)
The challenging severity of some infections, especially in critically ill patients, makes the diffusion of antimicrobial drugs within tissues one of the cornerstones of chemotherapy. The knowledge of how antibacterial agents penetrate tissues may com
Externí odkaz:
https://doaj.org/article/2f73a99cbf1a4ee087d666b865623b75
Autor:
Giuseppe Balice, Claudio Passino, Maria Grazia Bongiorni, Luca Segreti, Alessandro Russo, Marianna Lastella, Giacomo Luci, Marco Falcone, Antonello Di Paolo
Publikováno v:
Antibiotics, Vol 11, Iss 7, p 914 (2022)
Daptomycin pharmacokinetics may not depend on renal function only and it significantly differs between healthy volunteers and severely ill patients. Herein, we propose a population pharmacokinetics model based on 424 plasma daptomycin concentrations
Externí odkaz:
https://doaj.org/article/316bbd8236764523a3e3c52d9c61f0d1
Autor:
Federica Loscocco, Giuseppe Visani, Annamaria Ruzzo, Irene Bagaloni, Fabio Fuligni, Sara Galimberti, Antonello Di Paolo, Fabio Stagno, Patrizia Pregno, Mario Annunziata, Antonella Gozzini, Sara Barulli, Elisa Gabucci, Mauro Magnani, Alessandro Isidori
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Tyrosine kinase inhibitors (TKIs) have radically changed the outcome of chronic myeloid leukemia (CML) patients in the last 20 years. Moreover, the advent of second generation TKIs, namely nilotinib and dasatinib, have largely increased the number of
Externí odkaz:
https://doaj.org/article/43ad989d92e946a3a061a8934831529a