Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Antonello Merlino"'
Autor:
Rosanna Lucignano, Ilaria Stanzione, Giarita Ferraro, Rocco Di Girolamo, Carolina Cané, Angela Di Somma, Angela Duilio, Antonello Merlino, Delia Picone
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
For their easy and high-yield recombinant production, their high stability in a wide range of physico-chemical conditions and their characteristic hollow structure, ferritins (Fts) are considered useful scaffolds to encapsulate bioactive molecules. N
Externí odkaz:
https://doaj.org/article/7247e7bef97147b998c6cbcc54bf93fc
Autor:
Daria Maria Monti, Domenico Loreto, Ilaria Iacobucci, Giarita Ferraro, Alessandro Pratesi, Luigi D’Elia, Maria Monti, Antonello Merlino
Publikováno v:
Pharmaceuticals, Vol 15, Iss 4, p 425 (2022)
β-lactoglobulin is the major component of whey. Here, the adduct formed upon the reaction of the protein with oxaliplatin (OXA) has been prepared, structurally characterized by X-ray crystallography and electrospray ionization–mass spectrometry, a
Externí odkaz:
https://doaj.org/article/1f8ffdfd56444738b4f498e1e0bb7aff
Autor:
Daniele Florio, Maria Cuomo, Ilaria Iacobucci, Giarita Ferraro, Ahmed M. Mansour, Maria Monti, Antonello Merlino, Daniela Marasco
Publikováno v:
Pharmaceuticals, Vol 13, Iss 8, p 171 (2020)
Three Ru(II)-based CO-releasing molecules featuring bidentate benzimidazole and terpyridine derivatives as ligands were investigated for their ability to modulate the aggregation process of the second helix of the C-terminal domain of nucleophosmin 1
Externí odkaz:
https://doaj.org/article/3408f42cee084455b44555f64cf51d03
Autor:
Daniele Florio, Ilaria Iacobucci, Giarita Ferraro, Ahmed M. Mansour, Giancarlo Morelli, Maria Monti, Antonello Merlino, Daniela Marasco
Publikováno v:
Pharmaceuticals, Vol 12, Iss 4, p 154 (2019)
The effect of analogue Pd(II)-, Pt(II)-, and Au(III) compounds featuring 2-(2′-pyridyl)benzimidazole on the aggregation propensity of amyloid-like peptides derived from Aβ and from the C-terminal domain of nucleophosmin 1 was investigated. Kinetic
Externí odkaz:
https://doaj.org/article/d0d70ef2c95744c7b7898723bd7c6d67
Autor:
Maria Grazia Bisconte, Mercedes Caldora, Gennaro Musollino, Giovanna Cardiero, Angela Flagiello, Gaetana La Porta, Laura Lagona, Romeo Prezioso, Gabriele Qualtieri, Carlo Gaudiano, Emilia Medulla, Antonello Merlino, Piero Pucci, Giuseppina Lacerra
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0115738 (2015)
We identified two new variants in the third exon of the α-globin gene in families from southern Italy: the Hb Rogliano, α1 cod108 ACC>AAC or α1[α108(G15)Thr→Asn] and the Hb Policoro, α2 cod124 TCC>CCC or α2[α124(H7)Ser→Pro]. The carriers s
Externí odkaz:
https://doaj.org/article/b830e96e5b0b48969d3ed102b916208d
Autor:
Joanna Skiba, Tytus Bernaś, Damian Trzybiński, Krzysztof Woźniak, Giarita Ferraro, Daniela Marasco, Antonello Merlino, Marsel Z. Shafikov, Rafał Czerwieniec, Konrad Kowalski
Publikováno v:
Molecules, Vol 22, Iss 5, p 809 (2017)
Two new neutral fac-[Re(CO)3(phen)L] compounds (1,2), with phen = 1,10-phenanthroline and L = O2C(CH2)5CH3 or O2C(CH2)4C≡CH, were synthetized in one-pot procedures from fac-[Re(CO)3(phen)Cl] and the corresponding carboxylic acids, and were fully ch
Externí odkaz:
https://doaj.org/article/95fcc4b2ce9540b591304f9ff9b0aea5
Autor:
Giarita Ferraro, Maddalena Paolillo, Giuseppe Sciortino, Federico Pisanu, Eugenio Garribba, Antonello Merlino
Publikováno v:
Inorganic Chemistry. 62:8407-8417
Autor:
Domenico Loreto, Basudev Maity, Taiki Morita, Hiroyuki Nakamura, Antonello Merlino, Takafumi Ueno
Publikováno v:
Inorganic Chemistry. 62:7515-7524
Publikováno v:
Inorganic Chemistry. 61:16458-16467
The interaction with proteins of metal-based drugs plays a crucial role in their transport, mechanism, and activity. For an active MLn complex, where L is the organic carrier, various binding modes (covalent and non-covalent, single or multiple) may
Autor:
Sara La Manna, Marilisa Leone, Ilaria Iacobucci, Alfonso Annuziata, Concetta Di Natale, Elena Lagreca, Anna Maria Malfitano, Francesco Ruffo, Antonello Merlino, Maria Monti, Daniela Marasco
Publikováno v:
Inorganic Chemistry. 61:3540-3552
Neurodegenerative diseases are often caused by uncontrolled amyloid aggregation. Hence, many drug discovery processes are oriented to evaluate new compounds that are able to modulate self-recognition mechanisms. Herein, two related glycoconjugate pen