Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Antonello, Pessi"'
Autor:
Concetta Ragone, Michele Minopoli, Vincenzo Ingangi, Giovanni Botti, Federica Fratangelo, Antonello Pessi, Maria Patrizia Stoppelli, Paolo Antonio Ascierto, Gennaro Ciliberto, Maria Letizia Motti, Maria Vincenza Carriero
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-16 (2017)
Abstract Background Accumulating evidence demonstrates that the Urokinase Receptor (uPAR) regulates tumor cell migration through its assembly in composite regulatory units with transmembrane receptors, and uPAR88–92 is the minimal sequence required
Externí odkaz:
https://doaj.org/article/3f3287fd62da493eaa830b099a0bd4e9
Autor:
Maria Vincenza Carriero, Katia Bifulco, Vincenzo Ingangi, Susan Costantini, Giovanni Botti, Concetta Ragone, Michele Minopoli, Maria Letizia Motti, Domenica Rea, Giosuè Scognamiglio, Gerardo Botti, Claudio Arra, Gennaro Ciliberto, Antonello Pessi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract The development of metastases is a multistep process that requires the activation of physiological and biochemical processes that govern migration, invasion and entry of metastatic cells into blood vessels. The urokinase receptor (uPAR) prom
Externí odkaz:
https://doaj.org/article/e00079ff18874aaea55c11698d809490
Autor:
Anandan Palani, Andrea R. Nawrocki, Federica Orvieto, Elisabetta Bianchi, Emanuela Mandić, Antonello Pessi, Chunhui Huang, Qiaolin Deng, Nathalie Toussaint, Erika Walsh, Vijay Reddy, Eric Ashley, Huaibing He, Sheena Mumick, Brian Hawes, Donald Marsh, Mark Erion, Ravi Nargund, Paul E. Carrington
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1248-1254
Peptide-based analogues of the gut-derived incretin hormone, glucagon-like peptide 1 (GLP1), stimulate insulin secretion in a glucose-dependent manner. Currently marketed GLP1 receptor (GLP1R) agonists are safe and effective in the management of Type
Autor:
Elena Scaglione, Francesco Salvatore, Chiara Pagliuca, Aurora Daniele, Antonello Pessi, Fortunata Carbone, Sandro Cosconati, Roberta Colicchio, Stefano Tomassi, Salvatore Di Maro, Irene Colavita, Maria Vincenza Carriero, Paola Salvatore, Giuseppe Matarese, Ersilia Nigro
Publikováno v:
The FASEB Journal. 35
Antibiotic resistance is becoming a severe obstacle in the fight against acute and chronic infectious diseases that accompany most degenerative illnesses from neoplasia to osteo-arthritis and obesity. Currently, the race is on to identify pharmaceuti
Autor:
Simon D. Scott, Saleena Ghanny, Erik F. Young, Antonello Pessi, Patricia Soteropoulos, Michael A. Skinner, George Carnell, Nigel J. Temperton, Efstathios S. Giotis, Krzysztof Lacek, Lin-Fa Wang, Wendy S. Barclay
Publikováno v:
Access Microbiology. 2
The diversity of subtypes within Influenza A recently expanded with identification of H17N10 and H18N11 from bats. To study the tropism and zoonotic potential of these viruses, we successfully produced lentiviral pseudotypes bearing haemagglutinin H1
Autor:
Aparna Talekar, Antonello Pessi, Fraser Glickman, Uttara Sengupta, Thomas Briese, Michael A Whitt, Cyrille Mathieu, Branka Horvat, Anne Moscona, Matteo Porotto
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e30538 (2012)
Emerging viruses including Nipah, Hendra, Lujo, and Junin viruses have enormous potential to spread rapidly. Nipah virus, after emerging as a zoonosis, has also evolved the capacity for human-to-human transmission. Most of the diseases caused by thes
Externí odkaz:
https://doaj.org/article/307493a1871c441a8f21c1f93bd2bed2
Autor:
Antonello Pessi, Annunziata Langella, Elena Capitò, Silvia Ghezzi, Elisa Vicenzi, Guido Poli, Thomas Ketas, Cyrille Mathieu, Riccardo Cortese, Branka Horvat, Anne Moscona, Matteo Porotto
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36833 (2012)
Fusion between the viral and target cell membranes is an obligatory step for the infectivity of all enveloped virus, and blocking this process is a clinically validated therapeutic strategy.Viral fusion is driven by specialized proteins which, althou
Externí odkaz:
https://doaj.org/article/61857899e64549c3ae6e2df80ae40d36
Autor:
Federica Orvieto, Antonello Pessi, Brian Hawes, Paul E. Carrington, Licia Tomei, Armin Lahm, Sheena Mumick, Anandan Palani, Francesco Frattolillo, Valentina Di Biasio, Elisabetta Bianchi, Anna Demartis, Elisa Beghetto
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
A promising emerging area for the treatment of obesity and diabetes is combinatorial hormone therapy, where single-molecule peptides are rationally designed to integrate the complementary actions of multiple endogenous metabolically-related hormones.
Autor:
Matteo Porotto, Barry Rockx, Christine C Yokoyama, Aparna Talekar, Ilaria Devito, Laura M Palermo, Jie Liu, Riccardo Cortese, Min Lu, Heinz Feldmann, Antonello Pessi, Anne Moscona
Publikováno v:
PLoS Pathogens, Vol 6, Iss 10, p e1001168 (2010)
In the paramyxovirus cell entry process, receptor binding triggers conformational changes in the fusion protein (F) leading to viral and cellular membrane fusion. Peptides derived from C-terminal heptad repeat (HRC) regions in F have been shown to in
Externí odkaz:
https://doaj.org/article/7321bb26fcdb44f9915cb3eae907aa3e
Autor:
Olga Scudiero, Daniela Sarnataro, Francesco Salvatore, Ersilia Nigro, Aurora Daniele, Antonello Pessi, Irene Colavita
Publikováno v:
Journal of Peptide Science. 23:303-310
'Privileged scaffolds' are molecular frameworks which have been successfully exploited for small molecule drug discovery. Peptide privileged scaffolds, featuring a strictly conserved multiple-disulfide framework and high variability in the rest of th