Výsledky vyhledávání - "Antonella Vardeu"

Akademický článek

The effect of cardioplegic supplementation with sildenafil on cardiac energetics in a piglet model of cardiopulmonary bypass and cardioplegic arrest with warm or cold cardioplegia

Autor: Katie L. Skeffington, Eltayeb Mohamed Ahmed, Filippo Rapetto, Guillaume Chanoit, Andrew R. Bond, Antonella Vardeu, Mohamed T. Ghorbel, M-Saadeh Suleiman, Massimo Caputo

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 10 (2023)

Cardioplegic cardioprotection strategies used during paediatric open-heart surgery remain suboptimal. Sildenafil, a phosphodiesterase 5 (PDE-5) inhibitor, has been shown to be cardioprotective against ischemia/reperfusion injury in a variety of exper

Externí odkaz: https://doaj.org/article/e1676eda77224791b18921d484a6a09d

Zobrazit plný text záznamu

Akademický článek

Intravenous administration of viral vectors expressing prostate cancer antigens enhances the magnitude and functionality of CD8+ T cell responses

Autor: Thomas Evans, Ian McDonald, Charlotte Davis, Katie Anderson, Antonella Vardeu, Guilherme Stahlberg, Barsha Thapa, Kinga Piotrowska, Margaret A Marshall, Vicky Wheeler, Sarah Sebastian

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 11 (2022)

Background The use of immunotherapeutic vaccination in prostate cancer is a promising approach that likely requires the induction of functional, cytotoxic T cells . The experimental approach described here uses a well-studied adenovirus-poxvirus hete

Externí odkaz: https://doaj.org/article/a12c3a2b243043cdb03a5800b4b12ce3

Zobrazit plný text záznamu

Supplementary Data from Tebentafusp, A TCR/Anti-CD3 Bispecific Fusion Protein Targeting gp100, Potently Activated Antitumor Immune Responses in Patients with Metastatic Melanoma

Autor: Mario Sznol, Ita O’Kelly, Jacob Hurst, Sion Lewis, Sarah Stanhope, Revashnee Naidoo, Emma Leach, Antonella Vardeu, Avinash Gupta, Omid Hamid, Alexander N. Shoushtari, Alan Anthoney, Thomas R. Jeffry Evans, Neil M. Steven, Jeffrey R. Infante, Pippa Corrie, Victoria K. Woodcock, Cheryl McAlpine, Mark R. Middleton

Supplementary material

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c150f85250c5fc5cf0680722bad89c5b
https://doi.org/10.1158/1078-0432.22476341.v1

Zobrazit plný text záznamu

Data from Tebentafusp, A TCR/Anti-CD3 Bispecific Fusion Protein Targeting gp100, Potently Activated Antitumor Immune Responses in Patients with Metastatic Melanoma

Purpose:Tebentafusp is a first-in-class bispecific fusion protein designed to target gp100 (a melanoma-associated antigen) through a high affinity T-cell receptor (TCR) binding domain and an anti-CD3 T-cell engaging domain, which redirects T cells to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ccbf030ab20eb31d6aefca0fa390978
https://doi.org/10.1158/1078-0432.c.6529373

Zobrazit plný text záznamu

Tebentafusp, A TCR/Anti-CD3 Bispecific Fusion Protein Targeting gp100, Potently Activated Antitumor Immune Responses in Patients with Metastatic Melanoma

Autor: Alexander N. Shoushtari, Neil Steven, Cheryl McAlpine, Jeffrey R. Infante, Revashnee Naidoo, Sarah Stanhope, Ita O’Kelly, Omid Hamid, Victoria K Woodcock, Pippa Corrie, Mark R. Middleton, Emma Leach, Alan Anthoney, Sion Lewis, Jacob Hurst, Avinash Gupta, Antonella Vardeu, Thomas R. Jeffry Evans, Mario Sznol

Publikováno v: Clinical Cancer Research. 26:5869-5878

Purpose: Tebentafusp is a first-in-class bispecific fusion protein designed to target gp100 (a melanoma-associated antigen) through a high affinity T-cell receptor (TCR) binding domain and an anti-CD3 T-cell engaging domain, which redirects T cells t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d07ec411dced4f8bcfe606fe87d76573
https://doi.org/10.1158/1078-0432.ccr-20-1247

Zobrazit plný text záznamu

Intravenous administration of viral vectors expressing prostate cancer antigens enhances the magnitude and functionality of CD8+ T cell responses

Autor: Antonella Vardeu, Charlotte Davis, Ian McDonald, Guilherme Stahlberg, Barsha Thapa, Kinga Piotrowska, Margaret A Marshall, Thomas Evans, Vicky Wheeler, Sarah Sebastian, Katie Anderson

Publikováno v: Journal for ImmunoTherapy of Cancer. 10:e005398

BackgroundThe use of immunotherapeutic vaccination in prostate cancer is a promising approach that likely requires the induction of functional, cytotoxic T cells . The experimental approach described here uses a well-studied adenovirus-poxvirus heter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18bf784f4d45bfe535cb84a59ceab1c
https://doi.org/10.1136/jitc-2022-005398

Zobrazit plný text záznamu

MicroRNAs as potential biomarkers in congenital heart surgery

Autor: Giovanni Biglino, Kerrie L. Ford, Serban Stoica, Antonella Vardeu, Massimo Caputo, Mustafa Zakkar, Costanza Emanueli, Domenico Bruno, Andrew D Mumford, Gianni D Angelini, Dan M Dorobantu

Publikováno v: Stoica, S C, Dorobantu, D M, Vardeu, A, Biglino, G, Ford, K L, Bruno, D V, Zakkar, M, Mumford, A, Angelini, G D, Caputo, M & Emanueli, C 2019, ' MicroRNAs as potential biomarkers in congenital heart surgery ', Journal of Thoracic and Cardiovascular Surgery . https://doi.org/10.1016/j.jtcvs.2019.03.062

Objective: Pediatric congenital heart surgery (CHS)involves intracardiac, valvular, and vascular repairs. Accurate tools to aid short-term outcome prediction in pediatric CHS are lacking. Clinical scores, such as the vasoactive-inotrope score and ven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d2e1372c37850655efc88d59baba48
https://doi.org/10.1016/j.jtcvs.2019.03.062

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání