Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Antonella Vallario"'
Autor:
Massimo Aglietta, Dario Sangiolo, Paola Circosta, Katia Vitaggio, Alessandro Cignetti, Fabrizio Carnevale-Schianca, Angela Rita Elia, Maja Todorovic, Massimo Geuna, Antonella Vallario
Publikováno v:
Immunotherapy. 10(9)
Allogeneic hematopoietic cell transplantation (allo-HCT) is an adoptive immunotherapy strategy whose effectiveness relies on graft-versus-tumor (GVT) effect. We explored the feasibility of enhancing GVT after allo-HCT by peptide vaccination. Two myel
Autor:
Antonella Vallario, Luca Tamagnone, Massimiliano Mazzone, Peter Carmeliet, Charlotte Rolny, Lorena Capparuccia, Alessandro Cignetti, Enzo Medico, Andrea Casazza, Paolo M. Comoglio
Publikováno v:
The Journal of Experimental Medicine
Semaphorins are a large family of evolutionarily conserved morphogenetic molecules originally identified for their repelling role in axonal guidance. Intriguingly, semaphorins have recently been implicated in cancer progression (Neufeld, G., T. Lange
Autor:
Antonia Follenzi, Antonella Vallario, Daniela Gottardi, Luigi Naldini, Federico Caligaris-Cappio, Paola Circosta, Alessandro Cignetti, Antonio Capaldi
Publikováno v:
Human Gene Therapy. 16:445-456
The development of immunotherapy approaches designed to obtain tumor-specific T cells might help eradicate residual malignant cells in multiple myeloma (MM) patients. To this end, we used autologous primary MM cells as antigen-presenting cells (APC).
Autor:
Ulf Thunberg, Giovanna Rege-Cambrin, Federico Caligaris-Cappio, Kenneth Nilsson, Alessandra Faldella, Paola Circosta, Michela Aragno, A Alfarano, Antonella Vallario, Daniela Gottardi, Alessandra Stacchini
Publikováno v:
Leukemia Research. 23:127-136
We report the establishment and characterization of two cell lines, MEC1 and MEC2, that grew spontaneously on two subsequent occasions from the peripheral blood (PB) of a patient with B-chronic lymphocytic leukemia (B-CLL) in prolymphocytoid transfor
Autor:
Antonella Vallario, Katiuscia Vitaggio, Francesca Orso, Loretta Gammaitoni, Stefania Stella, Maja Todorovic, Paola Circosta, Angela Rita Elia, Elisa Vigna, Alessandro Cignetti, Claudia Giachino, Massimo Geuna, Luisa Granziero, Antonia Follenzi, Dario Sangiolo
Publikováno v:
Human gene therapy. 20(12)
We investigated the possibility of introducing exogenous T cell receptor (TCR) genes into T cells by lentiviral transduction, without prior stimulation of endogenous TCR with anti-CD3. TCR transfer is used to impose tumor antigen specificity on recip
Autor:
Antonella Vallario, Valeria Podestà, Simone Di Micco, Ambra A. Grolla, Giovanni Sorba, Giuseppe Bifulco, Gian Cesare Tron, Pier Luigi Canonico, Maria Giovanna Chini, Tracey Pirali, Armando A. Genazzani
HDAC inhibitors show great promise for the treatment of cancer. As part of a broader effort to explore the SAR of HDAC inhibitors, synthesis, biological evaluation, and molecular docking of novel Ugi products containing a zinc-chelating moiety are pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13afb90cfef01ef11c1826f2e2cd76b
http://hdl.handle.net/11386/1960355
http://hdl.handle.net/11386/1960355
Autor:
Fabrizio Carnevale-Schianca, Katiuscia Vitaggio, Massimo Geuna, Dario Sangiolo, Emanuela Martinuzzi, Alessandro Cignetti, Antonio Capaldi, Richard A. Nash, Massimo Aglietta, Antonella Vallario, Noela Jordaney, Maja Todorovic, Laura Casorzo
Publikováno v:
International immunology. 20(7)
Donor-derived cytokine-induced killer (CIK) can be infused as adoptive immunotherapy after hematopoietic cell transplant (HCT). Promising results were recently reported in HLA-identical HCT, where mild grafts versus host (GVH) events were observed. T
Autor:
Giuseppina Prato, Alessandro Cignetti, Paola Circosta, Giovanni Rolla, Monica Boita, Stefania Stella, Sara Mariani, Enrico Heffler, Antonella Vallario, Giuseppe Guida, Antonino Sottile, Roberta Bergia
Churg Strauss Syndrome (CSS) is a systemic vasculitis in which oligoclonal T cell expansions might be involved in the pathogenesis. Combined analysis of TCR-Vbeta expression profile by flow cytometry and of TCR gene rearrangement by heteroduplex PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ec26494ea5e8005580b38e0bb0289f
http://hdl.handle.net/2318/57813
http://hdl.handle.net/2318/57813
Autor:
Elisa Sperti, Giovanni De Rosa, Massimo Geuna, Katiuscia Vitaggio, Massimo Aglietta, Giovanni Grignani, Dario Sangiolo, Alessandro Cignetti, Giorgio Lambertenghi-Deliliers, Antonella Vallario, Richard A. Nash, Fabrizio Carnevale-Schianca, R. Ferraris, Anna Rosa Bucci, Edoardo Benedetti, Marco Fizzotti, Antonio Capaldi, Delia Rota-Scalabrini, A. Ricchiardi, Antonino Sottile, Marco Gatti
A pilot study was conducted to evaluate safety and activity of nonmyeloablative allogeneic hematopoietic cell transplantation (HCT) in colorectal carcinoma (CRC) and to determine whether a T-cell response to a tumor-associated antigen (TAA) was induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081a1fc23fc2786e23070d7eb18adbb8
http://hdl.handle.net/2318/30613
http://hdl.handle.net/2318/30613
Autor:
Annalisa Camporeale, Paola Circosta, Cristina Scielzo, Luisa Granziero, Antonella Vallario, Paolo Ghia, Federico Caligaris-Cappio
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783540252795
Selected microenvironmental stimuli confer to leukemic cells a growth advantage and an extended survival. We aimed at dissecting the differential support provided by the different cellular components of the microenvironment where CLL cells accumulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::330832d00f9e0d2aa334d4588f80538d
https://doi.org/10.1007/3-540-29933-5_8
https://doi.org/10.1007/3-540-29933-5_8