Výsledky vyhledávání - "Antonella Spila"

Akademický článek

Machine learning approach to predict medication overuse in migraine patients

Autor: Patrizia Ferroni, Fabio M. Zanzotto, Noemi Scarpato, Antonella Spila, Luisa Fofi, Gabriella Egeo, Alessandro Rullo, Raffaele Palmirotta, Piero Barbanti, Fiorella Guadagni

Publikováno v: Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1487-1496 (2020)

Machine learning (ML) is largely used to develop automatic predictors in migraine classification but automatic predictors for medication overuse (MO) in migraine are still in their infancy. Thus, to understand the benefits of ML in MO prediction, we

Externí odkaz: https://doaj.org/article/e54009756a794769988ad947af78bbd4

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Akademický článek

Protective Effect of Antioxidants in Nitric Oxide/COX-2 Interaction during Inflammatory Pain: The Role of Nitration

Autor: Sara Ilari, Concetta Dagostino, Valentina Malafoglia, Filomena Lauro, Luigino Antonio Giancotti, Antonella Spila, Stefania Proietti, Domenica Ventrice, Milena Rizzo, Micaela Gliozzi, Ernesto Palma, Fiorella Guadagni, Daniela Salvemini, Vincenzo Mollace, Carolina Muscoli

Publikováno v: Antioxidants, Vol 9, Iss 12, p 1284 (2020)

In clinical practice, inflammatory pain is an important, unresolved health problem, despite the utilization of non-steroidal anti-inflammatory drugs (NSAIDs). In the last decade, different studies have proven that reactive oxygen species (ROS) and re

Externí odkaz: https://doaj.org/article/b42f5487aaff4d0db40ad2b1d198e625

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Data from Brachyury, a Driver of the Epithelial–Mesenchymal Transition, Is Overexpressed in Human Lung Tumors: An Opportunity for Novel Interventions against Lung Cancer

Autor: Claudia Palena, Jeffrey Schlom, Kwong-Yok Tsang, Joanne Tucker, Bruce Huang, Duane Hamilton, Mary Litzinger, Leopoldo Costarelli, Raffaele Palmirotta, Jhessica Alessandroni, Antonella Spila, Fiorella Guadagni, Romaine I. Fernando, Mario Roselli

Purpose: The epithelial–mesenchymal transition (EMT) is emerging as a critical factor for the progression and metastasis of carcinomas, as well as drug resistance. The T-box transcription factor Brachyury has been recently characterized as a driver

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12904b60e4e85f0ff2f23310b6aec26b
https://doi.org/10.1158/1078-0432.c.6520718.v1

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Supplementary Table 1 from Brachyury, a Driver of the Epithelial–Mesenchymal Transition, Is Overexpressed in Human Lung Tumors: An Opportunity for Novel Interventions against Lung Cancer

PDF file, 62KB, Analysis of Brachyury gene copy number and promoter methylation status.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3418e2c137f44116ff0e3b3d2f9f0397
https://doi.org/10.1158/1078-0432.22446329.v1

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Supplementary Table 2 from Brachyury, a Driver of the Epithelial–Mesenchymal Transition, Is Overexpressed in Human Lung Tumors: An Opportunity for Novel Interventions against Lung Cancer

PDF file, 55KB, Number and percentage of tissues from adult non-cancer subjects that were positive for Brachyury expression by immunohistochemistry.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f61870cfed56b4d92e5d676f5cdfab7
https://doi.org/10.1158/1078-0432.22446326

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Supplementary Table 3 from Brachyury, a Driver of the Epithelial–Mesenchymal Transition, Is Overexpressed in Human Lung Tumors: An Opportunity for Novel Interventions against Lung Cancer

PDF file, 113KB, Patient characteristics for samples in human lung cancer cDNA arrays.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0970eab7cc93ecf2472766fb4518f3ed
https://doi.org/10.1158/1078-0432.22446323.v1

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Machine learning approach to predict medication overuse in migraine patients

Autor: Fabio Massimo Zanzotto, Antonella Spila, Piero Barbanti, Gabriella Egeo, Patrizia Ferroni, Alessandro Rullo, Raffaele Palmirotta, Noemi Scarpato, Luisa Fofi, Fiorella Guadagni

Publikováno v: Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 1487-1496 (2020)
Computational and Structural Biotechnology Journal

Graphical abstract
Highlights • Medication overuse is related to chronicization and medication-overuse headache. • Prediction of medication overuse (MO) is a challenge in the management of migraine. • Machine learning and random optimizati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8417bad483ef751fb083731a2f1c4de8
https://doi.org/10.1016/j.csbj.2020.06.006

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Association of LTA and SOD Gene Polymorphisms with Cerebral White Matter Hyperintensities in Migraine Patients

Autor: Patrizia Ferroni, Raffaele Palmirotta, Gabriella Egeo, Cinzia Aurilia, Maria Giovanna Valente, Antonella Spila, Alberto Pierallini, Piero Barbanti, Fiorella Guadagni

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 13781

White matter hyperintensities (WMHs) in migraine could be related to inflammatory and antioxidant events. The aim of this study is to verify whether migraine patients with WMHs carry a genetic pro-inflammatory/pro-oxidative status. To test this hypot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63b0f1b72f3512b854a8a7f12b2b36d
https://doi.org/10.3390/ijms232213781

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Protective Effect of Antioxidants in Nitric Oxide/COX-2 Interaction during Inflammatory Pain: The Role of Nitration

Autor: D. Ventrice, Valentina Malafoglia, Sara Ilari, Stefania Proietti, Fiorella Guadagni, Daniela Salvemini, Luigino Antonio Giancotti, Milena Rizzo, Ernesto Palma, Carolina Muscoli, Filomena Lauro, Micaela Gliozzi, Vincenzo Mollace, Antonella Spila, Concetta Dagostino

Publikováno v: Antioxidants, Vol 9, Iss 1284, p 1284 (2020)
Antioxidants
Volume 9
Issue 12

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffdf6f058b47fa568a0a8e99c8bf8c0
https://www.mdpi.com/2076-3921/9/12/1284

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Circulating Biomarkers in Migraine: New Opportunities for Precision Medicine

Autor: Antonella Spila, Cinzia Aurilia, Luisa Fofi, Patrizia Ferroni, Gabriella Egeo, Fiorella Guadagni, Piero Barbanti, Federica Fratangeli

Publikováno v: Current medicinal chemistry. 26(34)

Background: Migraine is the most common neurological disorder and the second most disabling human condition, whose pathogenesis is favored by a combination of genetic, epigenetic, and environmental factors. In recent years, several efforts have been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d648c1d101ed1443956db4b07c06ff
https://pubmed.ncbi.nlm.nih.gov/29932027

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