A novel neuroferritinopathy mouse model (FTL 498InsTC) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits

Autor: Federica Maccarinelli, Antonella Pagani, Anna Cozzi, Franca Codazzi, Giuseppina Di Giacomo, Sara Capoccia, Stefania Rapino, Dario Finazzi, Letterio Salvatore Politi, Francesca Cirulli, Marco Giorgio, Ottavio Cremona, Fabio Grohovaz, Sonia Levi

Publikováno v: Neurobiology of Disease, Vol 81, Iss , Pp 119-133 (2015)

Neuroferritinopathy is a rare genetic disease with a dominant autosomal transmission caused by mutations of the ferritin light chain gene (FTL). It belongs to Neurodegeneration with Brain Iron Accumulation, a group of disorders where iron dysregulati

Externí odkaz: https://doaj.org/article/ab480e02c5734d1caa9262644f163cea

Lipophilic dye-compatible brain clearing technique allowing correlative magnetic resonance/high-resolution fluorescence imaging in rat models of glioblastoma

Autor: Alessandra Biffi, Giorgia Spano, Gianluca Brugnara, Antonella Pagani, Cesare Covino, Letterio S. Politi, Rossella Galli, Marco Peviani

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)

In this work we optimized a novel approach for combining in vivo MRI and ex vivo high-resolution fluorescence microscopy that involves: (i) a method for slicing rat brain tissue into sections with the same thickness and spatial orientation as in in v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029836ea8e6c85dd4c57921434e6064a
https://pubmed.ncbi.nlm.nih.gov/33087842

Characterization of biological features of a rat F98 GBM model: a PET-MRI study with [18F]FAZA and [18F]FDG

Autor: Sara Belloli a, b, c, Andrea Brioschi d, Letterio Salvatore Politi e, Francesca Ronchetti d, Sara Calderoni d, Isabella Raccagni b, Antonella Pagani e, Cristina Monterisi a, Francesco Zenga f, g, Gianpaolo Zara h, Ferruccio Fazio a, Alessandro Mauro d, f, Rosa Maria Moresco a

Publikováno v: Nuclear medicine and biology 40 (2013): 831–840. doi:10.1016/j.nucmedbio.2013.05.004
info:cnr-pdr/source/autori:Sara Belloli a, b, c, Andrea Brioschi d, Letterio Salvatore Politi e, Francesca Ronchetti d, Sara Calderoni d, Isabella Raccagni b, Antonella Pagani e, Cristina Monterisi a, b, c, Francesco Zenga f, g, Gianpaolo Zara h, Ferruccio Fazio a, b, c, Alessandro Mauro d, f, Rosa Maria Moresco a, b, c,/titolo:Characterization of biological features of a rat F98 GBM model: A PET-MRI study with [(18)F]FAZA and [(18)F]FDG/doi:10.1016%2Fj.nucmedbio.2013.05.004/rivista:Nuclear medicine and biology/anno:2013/pagina_da:831/pagina_a:840/intervallo_pagine:831–840/volume:40

Introduction The prognosis of malignant gliomas remains largely unsatisfactory for the intrinsic characteristics of the pathology and for the delayed diagnosis. Multimodal imaging based on PET and MRI may assess the dynamics of disease onset and prog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67cd1319f41836f886e89246736a8141
http://hdl.handle.net/10281/48836