Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Antonella Nicolò"'
Autor:
Mirja Harms, Monica M.W. Habib, Simona Nemska, Antonella Nicolò, Andrea Gilg, Nico Preising, Pandian Sokkar, Sara Carmignani, Martina Raasholm, Gilbert Weidinger, Gönül Kizilsavas, Manfred Wagner, Ludger Ständker, Ashraf H. Abadi, Hassan Jumaa, Frank Kirchhoff, Nelly Frossard, Elsa Sanchez-Garcia, Jan Münch
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2694-2708 (2021)
Aberrant CXCR4/CXCL12 signaling is involved in many pathophysiological processes such as cancer and inflammatory diseases. A natural fragment of serum albumin, named EPI-X4, has previously been identified as endogenous peptide antagonist and inverse
Externí odkaz:
https://doaj.org/article/877b759cf88f4e9a87e25611fe551bb2
Autor:
Antonella Nicolò, Timm Amendt, Omar El Ayoubi, Marc Young, Stephanie Finzel, Makbule Senel, Reinhard E. Voll, Hassan Jumaa
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Rheumatoid arthritis is an autoimmune disease characterized by joint inflammation due to autoantibodies targeting multiple self-proteins. Most patients with poor prognosis show elevated titers of IgM antibodies specifically binding to IgG. Such autor
Externí odkaz:
https://doaj.org/article/6859fa3d505e4ce3bf14bb6b4b83ddae
Autor:
Domenico Conza, Paola Mirra, Francesca Fiory, Luigi Insabato, Antonella Nicolò, Francesco Beguinot, Luca Ulianich
Publikováno v:
Cells, Vol 12, Iss 17, p 2182 (2023)
The biguanide drug metformin is widely used in type 2 diabetes mellitus therapy, due to its ability to decrease serum glucose levels, mainly by reducing hepatic gluconeogenesis and glycogenolysis. A considerable number of studies have shown that metf
Externí odkaz:
https://doaj.org/article/6ecf599bcba3436e8282ee0c4a96c615
Autor:
Alessia Leone, Antonella Nicolò, Immacolata Prevenzano, Federica Zatterale, Michele Longo, Antonella Desiderio, Rosa Spinelli, Michele Campitelli, Domenico Conza, Gregory Alexander Raciti, Francesco Beguinot, Cecilia Nigro, Claudia Miele
Publikováno v:
Cells, Vol 12, Iss 13, p 1741 (2023)
Adipose-derived stem cells (ADSCs) play a crucial role in angiogenesis and repair of damaged tissues. However, in pathological conditions including diabetes, ADSC function is compromised. This work aims at evaluating the effect of Methylglyoxal (MGO)
Externí odkaz:
https://doaj.org/article/ae86b98c3888430b893c0a56643f7c45
Autor:
Andrea N. Mazzarello, Eva Gentner-Göbel, Marcus Dühren-von Minden, Tatyana N. Tarasenko, Antonella Nicolò, Gerardo Ferrer, Stefano Vergani, Yun Liu, Davide Bagnara, Kanti R. Rai, Jan A. Burger, Peter J. McGuire, Palash C. Maity, Hassan Jumaa, Nicholas Chiorazzi
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 2 (2022)
In chronic lymphocytic leukemia (CLL), the B cell receptor (BCR) plays a critical role in disease development and progression, as indicated by the therapeutic efficacy of drugs blocking BCR signaling. However, the mechanism(s) underlying BCR responsi
Externí odkaz:
https://doaj.org/article/66a5d21ed217411b9bb0675bdc0e82e4
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Advanced genome-wide association studies (GWAS) identified several transforming mutations in susceptible loci which are recognized as valuable prognostic markers in chronic lymphocytic leukemia (CLL) and B cell lymphoma (BCL). Alongside, robust genet
Externí odkaz:
https://doaj.org/article/1b17c74bdcbc4c69a13c3e025abce2e1
Autor:
Alessia Leone, Cecilia Nigro, Antonella Nicolò, Immacolata Prevenzano, Pietro Formisano, Francesco Beguinot, Claudia Miele
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
One of the hallmarks of cancer cells is their metabolic reprogramming, which includes the preference for the use of anaerobic glycolysis to produce energy, even in presence of normal oxygen levels. This phenomenon, known as “Warburg effect”, lead
Externí odkaz:
https://doaj.org/article/3117bd5e35df44038a8159231201f332
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Expression of the membrane-bound form of the immunoglobulin (Ig) as part of the antigen receptor is indispensable for both the development and the effector function of B cells. Among five known isotypes, IgM and IgD are the common B cell antigen rece
Externí odkaz:
https://doaj.org/article/3db2cb71f21c4acbb5ba7b7a2e6e0f06
Autor:
Cecilia Nigro, Alessia Leone, Francesca Fiory, Immacolata Prevenzano, Antonella Nicolò, Paola Mirra, Francesco Beguinot, Claudia Miele
Publikováno v:
Cells, Vol 8, Iss 7, p 749 (2019)
Dicarbonyl stress occurs when dicarbonyl metabolites (i.e., methylglyoxal, glyoxal and 3-deoxyglucosone) accumulate as a consequence of their increased production and/or decreased detoxification. This toxic condition has been associated with metaboli
Externí odkaz:
https://doaj.org/article/7f63f4dd3aca495e93078dc3d39f5e10
Autor:
Miele, Alessia Leone, Antonella Nicolò, Immacolata Prevenzano, Federica Zatterale, Michele Longo, Antonella Desiderio, Rosa Spinelli, Michele Campitelli, Domenico Conza, Gregory Alexander Raciti, Francesco Beguinot, Cecilia Nigro, Claudia
Publikováno v:
Cells; Volume 12; Issue 13; Pages: 1741
Adipose-derived stem cells (ADSCs) play a crucial role in angiogenesis and repair of damaged tissues. However, in pathological conditions including diabetes, ADSC function is compromised. This work aims at evaluating the effect of Methylglyoxal (MGO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::033458b559a142205edcbc9399919853