Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Antonella Monticelli"'
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-9 (2018)
Abstract Background In recent years, epigenetics has gained a central role in the understanding of the process of natural selection. It is now clear how environmental impacts on the methylome could promote methylation variability with direct effects
Externí odkaz:
https://doaj.org/article/594edfb5f6194a92a4e54862a3f82741
Autor:
Ermanno Florio, Simona Keller, Lorena Coretti, Ornella Affinito, Giovanni Scala, Francesco Errico, Annalisa Fico, Francesca Boscia, Maria Josè Sisalli, Mafalda Giovanna Reccia, Gennaro Miele, Antonella Monticelli, Antonella Scorziello, Francesca Lembo, Luca Colucci-D'Amato, Gabriella Minchiotti, Vittorio Enrico Avvedimento, Alessandro Usiello, Sergio Cocozza, Lorenzo Chiariotti
Publikováno v:
Epigenetics, Vol 12, Iss 1, Pp 41-54 (2017)
We performed ultra-deep methylation analysis at single molecule level of the promoter region of developmentally regulated D-Aspartate oxidase (Ddo), as a model gene, during brain development and embryonic stem cell neural differentiation. Single mole
Externí odkaz:
https://doaj.org/article/a9478b179b47438f8014f2f51a8cedd1
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114432 (2014)
The regions surrounding transcription start sites (TSSs) of genes play a critical role in the regulation of gene expression. At the same time, current evidence indicates that these regions are particularly stressed by transcription-related mutagenic
Externí odkaz:
https://doaj.org/article/f3b885a820b941b3ab61be917182d3e1
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27588 (2011)
Many decades of scientific investigation have proved the role of selective pressure in Homo Sapiens at least at the level of individual genes or loci. Nevertheless, there are examples of polygenic traits that are bound to be under selection, but stud
Externí odkaz:
https://doaj.org/article/d2fb3e781bb04c588d64f85dac03e4fb
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23156 (2011)
DNA methylation at CpG islands (CGIs) is one of the most intensively studied epigenetic mechanisms. It is fundamental for cellular differentiation and control of transcriptional potential. DNA methylation is involved also in several processes that ar
Externí odkaz:
https://doaj.org/article/2267b46016f84a0c80b6ea786966e834
Autor:
Daniele Marmolino, Mario Manto, Fabio Acquaviva, Paola Vergara, Ajay Ravella, Antonella Monticelli, Massimo Pandolfo
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10025 (2010)
BackgroundCells from individuals with Friedreich's ataxia (FRDA) show reduced activities of antioxidant enzymes and cannot up-regulate their expression when exposed to oxidative stress. This blunted antioxidant response may play a central role in the
Externí odkaz:
https://doaj.org/article/1ed16c65f7954b3bbaa18b4a705ff543
Autor:
Roberto Amato, Michele Pinelli, Antonella Monticelli, Davide Marino, Gennaro Miele, Sergio Cocozza
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7927 (2009)
Genetic differences both between individuals and populations are studied for their evolutionary relevance and for their potential medical applications. Most of the genetic differentiation among populations are caused by random drift that should affec
Externí odkaz:
https://doaj.org/article/3bafccbbe17f43ff968c6b2efa7a5a08
Autor:
Rossella Bruno, Franca Melfi, Antonella Monticelli, Sara Ricciardi, Paolo Piaggi, Greta Alì, Ornella Affinito, Sergio Cocozza, Antonio Chella, Anello Marcello Poma, Marco Lucchi, Gabriella Fontanini
Publikováno v:
Scientific Reports
Scientific reports (Nature Publishing Group) 9 (2019). doi:10.1038/s41598-019-40016-8
info:cnr-pdr/source/autori:Ali G.; Bruno R.; Poma A.M.; Affinito O.; Monticelli A.; Piaggi P.; Ricciardi S.; Lucchi M.; Melfi F.; Chella A.; Cocozza S.; Fontanini G./titolo:Whole transcriptome targeted gene quantification provides new insights on pulmonary sarcomatoid carcinomas/doi:10.1038%2Fs41598-019-40016-8/rivista:Scientific reports (Nature Publishing Group)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific reports (Nature Publishing Group) 9 (2019). doi:10.1038/s41598-019-40016-8
info:cnr-pdr/source/autori:Ali G.; Bruno R.; Poma A.M.; Affinito O.; Monticelli A.; Piaggi P.; Ricciardi S.; Lucchi M.; Melfi F.; Chella A.; Cocozza S.; Fontanini G./titolo:Whole transcriptome targeted gene quantification provides new insights on pulmonary sarcomatoid carcinomas/doi:10.1038%2Fs41598-019-40016-8/rivista:Scientific reports (Nature Publishing Group)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Pulmonary sarcomatoid carcinomas (PSC) are a rare group of lung cancer with a median overall survival of 9–12 months. PSC are divided into five histotypes, challenging to diagnose and treat. The identification of PSC biomarkers is warranted, but PS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317b18f003083813c306e4a6849b0c96
https://doi.org/10.1038/s41598-019-40016-8
https://doi.org/10.1038/s41598-019-40016-8
Autor:
Lorenzo Chiariotti, Domenico Palumbo, Antonella Monticelli, Sergio Cocozza, Ornella Affinito, Gennaro Miele, Ermanno Florio, Giovanni Scala
Publikováno v:
BMC Bioinformatics
BMC bioinformatics 17 (2016). doi:10.1186/s12859-016-1380-3
info:cnr-pdr/source/autori:Scala G.; Affinito O.; Palumbo D.; Florio E.; Monticelli A.; Miele G.; Chiariotti L.; Cocozza S./titolo:ampliMethProfiler: A pipeline for the analysis of CpG methylation profiles of targeted deep bisulfite sequenced amplicons/doi:10.1186%2Fs12859-016-1380-3/rivista:BMC bioinformatics/anno:2016/pagina_da:/pagina_a:/intervallo_pagine:/volume:17
BMC bioinformatics 17 (2016). doi:10.1186/s12859-016-1380-3
info:cnr-pdr/source/autori:Scala G.; Affinito O.; Palumbo D.; Florio E.; Monticelli A.; Miele G.; Chiariotti L.; Cocozza S./titolo:ampliMethProfiler: A pipeline for the analysis of CpG methylation profiles of targeted deep bisulfite sequenced amplicons/doi:10.1186%2Fs12859-016-1380-3/rivista:BMC bioinformatics/anno:2016/pagina_da:/pagina_a:/intervallo_pagine:/volume:17
Background CpG sites in an individual molecule may exist in a binary state (methylated or unmethylated) and each individual DNA molecule, containing a certain number of CpGs, is a combination of these states defining an epihaplotype. Classic quantifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec80735d5b05a47ba0b0159eeb10b27
https://doi.org/10.1186/s12859-016-1380-3
https://doi.org/10.1186/s12859-016-1380-3
Publikováno v:
PloS one 9 (2014). doi:10.1371/journal.pone.0114432
info:cnr-pdr/source/autori:Scala G.; Affinito O.; Miele G.; Monticelli A.; Cocozza S./titolo:Evidence for evolutionary and nonevolutionary forces shaping the distribution of human genetic variants near transcription start sites/doi:10.1371%2Fjournal.pone.0114432/rivista:PloS one/anno:2014/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
PLoS ONE, Vol 9, Iss 12, p e114432 (2014)
PLoS ONE
info:cnr-pdr/source/autori:Scala G.; Affinito O.; Miele G.; Monticelli A.; Cocozza S./titolo:Evidence for evolutionary and nonevolutionary forces shaping the distribution of human genetic variants near transcription start sites/doi:10.1371%2Fjournal.pone.0114432/rivista:PloS one/anno:2014/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
PLoS ONE, Vol 9, Iss 12, p e114432 (2014)
PLoS ONE
The regions surrounding transcription start sites (TSSs) of genes play a critical role in the regulation of gene expression. At the same time, current evidence indicates that these regions are particularly stressed by transcription-related mutagenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::858b4300112a5c46e75e45099791e0e6
http://hdl.handle.net/11588/593676
http://hdl.handle.net/11588/593676
