Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Antonella L. Bastone"'
Autor:
Antonella L. Bastone, Violetta Dziadek, Philipp John-Neek, Friederike Mansel, Jenni Fleischauer, Eric Agyeman-Duah, Dirk Schaudien, Oliver Dittrich-Breiholz, Adrian Schwarzer, Axel Schambach, Michael Rothe
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 515-533 (2023)
Safety assessment in retroviral vector-mediated gene therapy remains challenging. In clinical trials for different blood and immune disorders, insertional mutagenesis led to myeloid and lymphoid leukemia. We previously developed the In Vitro Immortal
Externí odkaz:
https://doaj.org/article/4d961949250f4d17b1e74ea409031a0e
Autor:
Susana Navarro, Sara Fañanas-Baquero, Michael Rothe, Isabel Ojeda-Perez, Rebeca Sanchez-Dominguez, Sergio López-Manzaneda, Virginia Nieto Romero, Oscar Quintana-Bustamante, Aída Garcia-Torralba, Andrea Molinos-Vicente, Jose-Carlos Segovia, Mariela Villanueva, Jonathan D. Schwartz, Eileen Nicoletti, Sonia Gutierrez, Juan A. Bueren, Omaira Alberquilla, María García-Bravo, Brian C. Beard, Juan C. Ramirez, Kenneth Law, Antonella L. Bastone
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 350-359 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Pyruvate kinase deficiency (PKD) is a rare autosomal recessive disorder caused by mutations in the PKLR gene. PKD is characterized by non-spherocytic hemolytic anemia of variable severity and may be fatal in some cases during early childhood. Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8952906c293b2aaba5d002b91b3f7d14
http://www.sciencedirect.com/science/article/pii/S2329050121001236
http://www.sciencedirect.com/science/article/pii/S2329050121001236
Autor:
Steven R. Talbot, Ute Modlich, Adrian Schwarzer, Hubert B. Gaspar, Axel Schambach, Rik Gijsbers, Michael Rothe, Anton Selich, Michael A. Morgan, Oliver Dittrich-Breiholz, Violetta Dziadek, Teng Cheong Ha, Juliane W. Schott, Bettina Weigel, Adrian J. Thrasher, Frank J. T. Staal, Antonella L. Bastone
Publikováno v:
Molecular Therapy, 29(12), 3383-3397. CELL PRESS
molecular therapy
Molecular therapy, 29(12):3383-3397
molecular therapy
Molecular therapy, 29(12):3383-3397
Hematopoietic stem cell gene therapy is emerging as a promising therapeutic strategy for many diseases of the blood and immune system. However, several individuals who underwent gene therapy in different trials developed hematological malignancies ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86fe6d1cdb3da7a5ee0b306f7e3216d
https://pubmed.ncbi.nlm.nih.gov/34174440
https://pubmed.ncbi.nlm.nih.gov/34174440