Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Antonella Gorini"'
Publikováno v:
Neurochemical research. 47(5)
Clonidine is an anti-hypertensive drug that inhibits the release of norepinephrine from pre-synaptic terminals binding to pre-synaptic α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2effaec0b8a45f875a9a994ce5a54c13
https://pubmed.ncbi.nlm.nih.gov/35099720
https://pubmed.ncbi.nlm.nih.gov/35099720
Publikováno v:
Neuroscience Letters. 694:74-79
Energy metabolism is fundamental to maintain Central Nervous System homeostasis because of high requirement of adenosine triphosphate (ATP), that is necessary to sustain neuronal events. During aging, changes in brain bioenergetics may influence the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2566f04bf79b60ed89c6c36b37eb7f3
https://doi.org/10.1016/j.neulet.2018.11.028
https://doi.org/10.1016/j.neulet.2018.11.028
Publikováno v:
Journal of Neurochemistry. 146:416-428
Glutamate is involved in cerebral ischemic injury, but its role has not been completely clarified and studies are required to understand how to minimize its detrimental effects, contemporarily boosting the positive ones. In fact, glutamate is not onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca1d1fb3d5c491ab199bddaeb82de17
https://doi.org/10.1111/jnc.14464
https://doi.org/10.1111/jnc.14464
Autor:
Antonella Gorini, Fabio Tascedda, Federica Ferrari, Nicoletta Brunello, Roberto Federico Villa
Publikováno v:
Neuroscience. 330:326-334
Brain bioenergetic abnormalities in mood disorders were detected by neuroimaging in vivo studies in humans. Because of the increasing importance of mitochondrial pathogenetic hypothesis of Depression, in this study the effects of sub-chronic treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ee662297d75b0044389c726bc5eca4
https://doi.org/10.1016/j.neuroscience.2016.05.051
https://doi.org/10.1016/j.neuroscience.2016.05.051
Publikováno v:
Journal of Proteome Research. 12:5422-5435
The effect of aging on hippocampus is often confounded by diseases that commonly occur in the elderly. In this research, functional proteomics was used to characterize age-related changes in energy metabolism of different neuronal pathways within the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76fcd81f6f18ec9034adbd3cca1bef02
https://doi.org/10.1021/pr400834g
https://doi.org/10.1021/pr400834g
Publikováno v:
Neuroscience. 248:414-426
The maximum rate ( V max ) of some enzymatic activities related to energy consumption was evaluated in synaptic plasma membranes from rat brain striatum, the synaptic energy state being a crucial factor in neurodegenerative diseases etiopathogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2e75eeccb43627a33adb791c8ae5fb
https://doi.org/10.1016/j.neuroscience.2013.06.027
https://doi.org/10.1016/j.neuroscience.2013.06.027
Autor:
Fabio Tascedda, Antonella Gorini, Nicoletta Brunello, Roberto Federico Villa, Federica Ferrari, Laura Bagini
Publikováno v:
Neuropharmacology. 121
Alterations in mitochondrial functions have been hypothesized to participate in the pathogenesis of depression, because brain bioenergetic abnormalities have been detected in depressed patients by neuroimaging in vivo studies. However, this hypothesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc3c1f7769e30e1a86b4e7059b74626
https://pubmed.ncbi.nlm.nih.gov/28431972
https://pubmed.ncbi.nlm.nih.gov/28431972
Publikováno v:
Neuroscience. 227:55-66
Ageing is one of the main risk factors for brain disorders. According to the neuroendocrine theory, ageing modifies the sensitivity of hypothalamus-pituitary-adrenal axis to homoeostatic signals coming from the cerebral cortex. The relationships betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fc9e8b923e3b8b2b27817d577b2d1f
https://doi.org/10.1016/j.neuroscience.2012.09.041
https://doi.org/10.1016/j.neuroscience.2012.09.041
Publikováno v:
Neurochemistry International. 61:1424-1432
The effect of aging and CDP-choline treatment (20 mg kg−1 body weight i.p. for 28 days) on the maximal rates (Vmax) of representative mitochondrial enzyme activities related to Krebs’ cycle (citrate synthase, α-ketoglutarate dehydrogenase, malat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84e6a27b05f80fb59ce598a8f5b49f0
https://doi.org/10.1016/j.neuint.2012.10.009
https://doi.org/10.1016/j.neuint.2012.10.009
Publikováno v:
Neurochemical Research. 27:861-870
Plasticity and relationships between individual ATPases linked to energy-utilizing systems of hippocampus, a very sensitive functional area to both age and ischemia, were studied during ageing on synaptic plasma membranes of 1-year-old “adult” an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::994dd07d7d76858824dc6a165cd85321
https://doi.org/10.1023/a:1020381829107
https://doi.org/10.1023/a:1020381829107