Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Antonella Favit"'
Autor:
L. Arthur Hewitt, Annika Lindsten, Stephen Gorny, Meghana Karnik‐Henry, Steven Kymes, Antonella Favit
Publikováno v:
Health Science Reports, Vol 4, Iss 1, Pp n/a-n/a (2021)
Abstract Background and Aims Patients with neurogenic orthostatic hypotension (nOH) due to autonomic dysfunction may also experience supine hypertension (defined as supine systolic blood pressure [SBP] ≥140 mmHg). Because pressor agents used to imp
Externí odkaz:
https://doaj.org/article/f62dbb9e762a4e71881f52772b9cf076
Autor:
Robert A. Hauser, Antonella Favit, L. Arthur Hewitt, Annika Lindsten, Stephen Gorny, Steven Kymes, Stuart H. Isaacson
Publikováno v:
Neurology and Therapy. 11:459-469
Autor:
Robert A, Hauser, Antonella, Favit, L Arthur, Hewitt, Annika, Lindsten, Stephen, Gorny, Steven, Kymes, Stuart H, Isaacson
Publikováno v:
Neurology and therapy. 11(1)
Droxidopa is approved to treat neurogenic orthostatic hypotension (nOH) symptoms in patients with autonomic failure based on short-term clinical trial data. Additional data on the long-term efficacy of droxidopa are needed. We have evaluated the 12-w
Autor:
Jay D. Amsterdam, Antonella Favit, George Moonsammy, Catherine M. Piontek, Anita H. Clayton, Ying Yang, Bryan J. Campbell
Publikováno v:
The Journal of Clinical Psychiatry. 68:1860-1866
Objective Spontaneous reports of sexual side effects were infrequent during placebo-controlled clinical trials of selegiline transdermal system (STS). The objective of this study was to examine the impact of STS 6 mg/24 hours on various domains of se
Autor:
M. Maral Mouradian, Tzvetelina Dimitrova, Abdulah Sherzai, Thomas N. Chase, Antonella Favit, William Bara-Jimenez
Publikováno v:
Movement Disorders. 19:1183-1186
Dopamine reuptake blockers, by enhancing and stabilizing intrasynaptic transmitter levels, could help palliate motor dysfunction in Parkinson's disease. This randomized, double-blind, placebo-controlled study compared the acute effects of the monoami
Autor:
Marjorie Gillespie, M. J. Morris, William Bara-Jimenez, Tzvetelina Dimitrova, Abdullah Sherzai, T. N. Chase, Francesco Bibbiani, Antonella Favit, M. Maral Mouradian
Publikováno v:
Neurology. 61:293-296
Observations in animal models suggest that A(2A) antagonists confer benefit by modulating dopaminergic effects on the striatal dysfunction associated with motor disability. This double-blind, placebo-controlled, proof-of-principle study evaluated the
Publikováno v:
Journal of Neurochemistry. 75:1258-1263
In many neurodegenerative disorders, such as Alzheimer's disease, inclusions containing ubiquitinated proteins have been found in the brain, suggesting a pathophysiological role for ubiquitin-mediated proteasomal degradation of neuronal proteins. Her
Autor:
Antonella Favit, Patricia Pinto-Garcia, Emily E. Clements, Alison J. White, Daniel J. Brat, Solomon H. Snyder, Andrew A. Pieper, Jill Conover, Seth Blackshaw, Ajay Verma, David K. Krug
Publikováno v:
Proceedings of the National Academy of Sciences. 97:1845-1850
Poly(ADP-ribose) polymerase (PARP) transfers ADP ribose groups from NAD + to nuclear proteins after activation by DNA strand breaks. PARP overactivation by massive DNA damage causes cell death via NAD + and ATP depletion. Heretofore, PARP has been th
Publikováno v:
Journal of Biological Chemistry. 274:33557-33564
In this report we investigated the correlation between cell morphology and regulation of cytosolic calcium homeostasis. Type I astrocytes were differentiated to stellate process-bearing cells by a 100-min exposure to cAMP. Differentiation of cortical
Autor:
Daniel L. Alkon, Lucas Pozzo-Miller, Wei Qin Zhao, Antonella Favit, Thomas J. Nelson, Shauna Yuan
Publikováno v:
Biochemical Journal. 341:423-433
Calexcitin (CE), a Ca2+- and GTP-binding protein, which is phosphorylated during memory consolidation, is shown here to co-purify with ryanodine receptors (RyRs) and bind to RyRs in a calcium-dependent manner. Nanomolar concentrations of CE released