Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Antonella Bugatti"'
Autor:
Michela Murdocca, Isabella Romeo, Gennaro Citro, Andrea Latini, Federica Centofanti, Antonella Bugatti, Francesca Caccuri, Arnaldo Caruso, Francesco Ortuso, Stefano Alcaro, Federica Sangiuolo, Giuseppe Novelli
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 891 (2024)
Genomic surveillance based on sequencing the entire genetic code of SARS-CoV-2 involves monitoring and studying genetic changes and variations in disease-causing organisms such as viruses and bacteria. By tracing the virus, it is possible to prevent
Externí odkaz:
https://doaj.org/article/f51beac551c24b8b92662b91163299cb
Autor:
Laura Brandolini, Michele d’Angelo, Rubina Novelli, Vanessa Castelli, Cristina Giorgio, Anna Sirico, Pasquale Cocchiaro, Francesco D’Egidio, Elisabetta Benedetti, Claudia Cristiano, Antonella Bugatti, Anna Ruocco, Pier Giorgio Amendola, Carmine Talarico, Candida Manelfi, Daniela Iaconis, Andrea Beccari, Andreza U. Quadros, Thiago M. Cunha, Arnaldo Caruso, Roberto Russo, Annamaria Cimini, Andrea Aramini, Marcello Allegretti
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-15 (2022)
Abstract Chemotherapy-induced peripheral neuropathy (CIPN) and hypersensitivity reactions (HSRs) are among the most frequent and impairing side effects of the antineoplastic agent paclitaxel. Here, we demonstrated that paclitaxel can bind and activat
Externí odkaz:
https://doaj.org/article/482c74a958854186b399d4cb5817aa32
Autor:
Daniela Iaconis, Licia Bordi, Giulia Matusali, Carmine Talarico, Candida Manelfi, Maria Candida Cesta, Mara Zippoli, Francesca Caccuri, Antonella Bugatti, Alberto Zani, Federica Filippini, Laura Scorzolini, Marco Gobbi, Marten Beeg, Arianna Piotti, Monica Montopoli, Veronica Cocetta, Silvia Bressan, Enrico M. Bucci, Arnaldo Caruso, Emanuele Nicastri, Marcello Allegretti, Andrea R. Beccari
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-9 (2022)
Abstract The new coronavirus SARS-CoV-2 is the causative agent of the COVID-19 pandemic, which so far has caused over 6 million deaths in 2 years, despite new vaccines and antiviral medications. Drug repurposing, an approach for the potential applica
Externí odkaz:
https://doaj.org/article/9f7ad91081cf4ba8bb1f706204ee8be2
Autor:
Daniela Iaconis, Francesca Caccuri, Candida Manelfi, Carmine Talarico, Antonella Bugatti, Federica Filippini, Alberto Zani, Rubina Novelli, Maria Kuzikov, Bernhard Ellinger, Philip Gribbon, Kristoffer Riecken, Francesca Esposito, Angela Corona, Enzo Tramontano, Andrea Rosario Beccari, Arnaldo Caruso, Marcello Allegretti
Publikováno v:
Viruses, Vol 15, Iss 5, p 1128 (2023)
During the COVID-19 pandemic, drug repurposing represented an effective strategy to obtain quick answers to medical emergencies. Based on previous data on methotrexate (MTX), we evaluated the anti-viral activity of several DHFR inhibitors in two cell
Externí odkaz:
https://doaj.org/article/b7bacb79c72b47389e3aeb9d63d3ca35
Autor:
Antonella Bugatti, Federica Filippini, Serena Messali, Marta Giovanetti, Cosetta Ravelli, Alberto Zani, Massimo Ciccozzi, Arnaldo Caruso, Francesca Caccuri
Publikováno v:
Viruses, Vol 15, Iss 2, p 332 (2023)
Severe COVID-19 is characterized by angiogenic features, such as intussusceptive angiogenesis, endothelialitis, and activation of procoagulant pathways. This pathological state can be ascribed to a direct SARS-CoV-2 infection of human lung ECs. Recen
Externí odkaz:
https://doaj.org/article/6539e47d90ca434c9315c37fbf8caa3b
Autor:
Francesca Caccuri, Alberto Zani, Serena Messali, Marta Giovanetti, Antonella Bugatti, Giovanni Campisi, Federica Filippini, Erika Scaltriti, Massimo Ciccozzi, Simona Fiorentini, Arnaldo Caruso
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background Since the first outbreak of SARS-CoV-2, the clinical characteristics of the Coronavirus Disease 2019 (COVID-19) have been progressively changed. Data reporting a viral intra-host and inter-host evolution favouring the appearance o
Externí odkaz:
https://doaj.org/article/7c9c67a167ae46ac864ccf530a5d8f07
Autor:
Antonella Bugatti, Federica Filippini, Marta Bardelli, Alberto Zani, Paola Chiodelli, Serena Messali, Arnaldo Caruso, Francesca Caccuri
Publikováno v:
Viruses, Vol 14, Iss 4, p 705 (2022)
Integrins represent a gateway of entry for many viruses and the Arg-Gly-Asp (RGD) motif is the smallest sequence necessary for proteins to bind integrins. All Severe Acute Respiratory Syndrome Virus type 2 (SARS-CoV-2) lineages own an RGD motif (aa 4
Externí odkaz:
https://doaj.org/article/694de9f5b0214413a77964f098dc9d89
Autor:
Francesca Caccuri, Antonella Bugatti, Alberto Zani, Antonella De Palma, Dario Di Silvestre, Ekta Manocha, Federica Filippini, Serena Messali, Paola Chiodelli, Giovanni Campisi, Simona Fiorentini, Fabio Facchetti, Pierluigi Mauri, Arnaldo Caruso
Publikováno v:
Microorganisms, Vol 9, Iss 7, p 1438 (2021)
SARS-CoV-2-associated acute respiratory distress syndrome (ARDS) and acute lung injury are life-threatening manifestations of severe viral infection. The pathogenic mechanisms that lead to respiratory complications, such as endothelialitis, intussusc
Externí odkaz:
https://doaj.org/article/a6bd25dff9ef4d079ce1bc8293cff614
Autor:
Silvia Agostini, Hashim Ali, Chiara Vardabasso, Antonio Fittipaldi, Ennio Tasciotti, Anna Cereseto, Antonella Bugatti, Marco Rusnati, Marina Lusic, Mauro Giacca
Publikováno v:
EBioMedicine, Vol 21, Iss C, Pp 170-181 (2017)
Besides its essential role in the activation of HIV-1 gene expression, the viral Tat protein has the unusual property of trafficking in and out of cells. In contrast to Tat internalization, the mechanism involved in extracellular Tat release has so f
Externí odkaz:
https://doaj.org/article/8a64912d25a74b23b44872da976b2a8e
Autor:
Ekta Manocha, Antonella Bugatti, Mirella Belleri, Alberto Zani, Stefania Marsico, Francesca Caccuri, Marco Presta, Arnaldo Caruso
Publikováno v:
Cells, Vol 10, Iss 2, p 259 (2021)
Avian reovirus p17 (ARV p17) is a non-structural protein known to activate autophagy, interfere with gene transcription and induce a significant tumor cell growth inhibition in vitro and in vivo. In this study, we show that ARV p17 is capable of exer
Externí odkaz:
https://doaj.org/article/3c2a7fdc1075430d85951b5e9748e512