Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Antonella, Bacchiocchi"'
Autor:
Xinxing Li, Tao Liu, Antonella Bacchiocchi, Mengxing Li, Wen Cheng, Tobias Wittkop, Fernando L Mendez, Yingyu Wang, Paul Tang, Qianqian Yao, Marcus W Bosenberg, Mario Sznol, Qin Yan, Malek Faham, Li Weng, Ruth Halaban, Hai Jin, Zhiqian Hu
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2188-2209 (2024)
Abstract While whole genome sequencing (WGS) of cell-free DNA (cfDNA) holds enormous promise for detection of molecular residual disease (MRD), its performance is limited by WGS error rate. Here we introduce AccuScan, an efficient cfDNA WGS technolog
Externí odkaz:
https://doaj.org/article/61e8893361234a0aaada760b5863e691
Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5
Autor:
Yanran Chen, Haomiao Su, Jianing Zhao, Zhenkun Na, Kevin Jiang, Antonella Bacchiocchi, Ken H. Loh, Ruth Halaban, Zhentian Wang, Xiongwen Cao, Sarah A. Slavoff
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113145- (2023)
Summary: The conserved WD40-repeat protein WDR5 interacts with multiple proteins both inside and outside the nucleus. However, it is currently unclear whether and how the distribution of WDR5 between complexes is regulated. Here, we show that an unan
Externí odkaz:
https://doaj.org/article/677a2dd973a34f00ba7e7ac83d8ed9a4
Autor:
Farshad Farshidfar, Kahn Rhrissorrakrai, Chaya Levovitz, Cong Peng, James Knight, Antonella Bacchiocchi, Juan Su, Mingzhu Yin, Mario Sznol, Stephan Ariyan, James Clune, Kelly Olino, Laxmi Parida, Joerg Nikolaus, Meiling Zhang, Shuang Zhao, Yan Wang, Gang Huang, Miaojian Wan, Xianan Li, Jian Cao, Qin Yan, Xiang Chen, Aaron M. Newman, Ruth Halaban
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Despite acral melanoma being the most common melanoma subtype in non-White individuals, its molecular drivers remain unknown. Here, the authors integrate genomic and clinical data from 104 patients and identify late-arising focal amplifications of ch
Externí odkaz:
https://doaj.org/article/b66dfca16a5a4cbdb29e51d65dceaf25
Autor:
Farshad Farshidfar, Kahn Rhrissorrakrai, Chaya Levovitz, Cong Peng, James Knight, Antonella Bacchiocchi, Juan Su, Mingzhu Yin, Mario Sznol, Stephan Ariyan, James Clune, Kelly Olino, Laxmi Parida, Joerg Nikolaus, Meiling Zhang, Shuang Zhao, Yan Wang, Gang Huang, Miaojian Wan, Xianan Li, Jian Cao, Qin Yan, Xiang Chen, Aaron M. Newman, Ruth Halaban
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/5a9b8651550c4098999829357759d0b2
Autor:
Roger S. Lo, Antoni Ribas, Georgina V. Long, Richard F. Kefford, Ruth Halaban, Jeffrey A. Sosman, Bartosz Chmielowski, Kimberly B. Dahlman, Antonella Bacchiocchi, Gulietta M. Pupo, Ramin Nazarian, Richard C. Koya, Xiangju Kong, Gatien Moriceau, Hubing Shi
PDF file - 76K, Relative expression levels of WT vs. P124SMEK1 in the YUKSI B-RAF/MEK1 double-mutant melanoma short-term culture. Genomic DNA (gDNA) and cDNA derived from YUKSI were subjected to exon 3 sequencing by the Sanger method. Relative peaks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c405dbf74d2b5be476508218c4e5ad4d
https://doi.org/10.1158/2159-8290.22528610.v1
https://doi.org/10.1158/2159-8290.22528610.v1
Autor:
David F. Stern, Marcus W. Bosenberg, Jonathan W. Haskins, Andrew Koo, Antonella Bacchiocchi, Ashok Chakraborty, Zongzhi Liu, Tisheeka Graham-Steed, James T. Platt, Casey G. Langdon, Matthew A. Held
XLSX file - 134K, Table S8. Most effective genotype-selective combinations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04dc85300f037ae5553db92c07acd09
https://doi.org/10.1158/2159-8290.22528703
https://doi.org/10.1158/2159-8290.22528703
Autor:
David F. Stern, Marcus W. Bosenberg, Jonathan W. Haskins, Andrew Koo, Antonella Bacchiocchi, Ashok Chakraborty, Zongzhi Liu, Tisheeka Graham-Steed, James T. Platt, Casey G. Langdon, Matthew A. Held
PDF file - 1.1MB, Figure S1. Single agent concentration-effect curves, related to Figure 1; Figure S2. Drug class and concentration choices for combinatorial drug screening, related to Figure 2; Figure S3, Mutant BRAF and mutant RAS selective drug pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eae7527ca5c5d876d8e33fa33b99f5d
https://doi.org/10.1158/2159-8290.22528706.v1
https://doi.org/10.1158/2159-8290.22528706.v1
Autor:
David F. Stern, Ruth Halaban, Michael Krauthammer, Marcus Bosenberg, Viswanathan Muthusamy, Antonella Bacchiocchi, Christina Ivins Zito, Sebastian Szpakowski, Garima Singhal, Kathryn Tworkoski
Supplementary Table 4 from Phosphoproteomic Screen Identifies Potential Therapeutic Targets in Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1152294b9e0f6b2225046346a8027861
https://doi.org/10.1158/1541-7786.22519209
https://doi.org/10.1158/1541-7786.22519209
Autor:
David F. Stern, Ruth Halaban, Michael Krauthammer, Marcus Bosenberg, Viswanathan Muthusamy, Antonella Bacchiocchi, Christina Ivins Zito, Sebastian Szpakowski, Garima Singhal, Kathryn Tworkoski
Supplementary Table Legends 1-6, Figure Legend 1 from Phosphoproteomic Screen Identifies Potential Therapeutic Targets in Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c016e6d655568c2d0a24d45d5e9d3670
https://doi.org/10.1158/1541-7786.22519200
https://doi.org/10.1158/1541-7786.22519200
Autor:
Roger S. Lo, Antoni Ribas, Georgina V. Long, Richard F. Kefford, Ruth Halaban, Jeffrey A. Sosman, Bartosz Chmielowski, Kimberly B. Dahlman, Antonella Bacchiocchi, Gulietta M. Pupo, Ramin Nazarian, Richard C. Koya, Xiangju Kong, Gatien Moriceau, Hubing Shi
PDF file - 46K, Rapid symptomatic relief in patient 12 treated with GSK2118436/dabrafenib. This patient's right axillary nodal tumor was punch-biopsied at baseline (prior to B-RAFi therapy), showing concurrent B-RAF/MEK1 mutations, and became non-pal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292239663dd4ffc0c03d75e07e807002
https://doi.org/10.1158/2159-8290.22528616
https://doi.org/10.1158/2159-8290.22528616