Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Anton Y Postnov"'
Publikováno v:
Clinical Medicine Insights: Cardiology, Vol 17 (2023)
For several decades, atherosclerosis has attracted the attention of researchers around the world. Even being a major cause of serious cardiovascular disease and events, atherosclerosis is still not fully understood. Despite the fact that the main pla
Externí odkaz:
https://doaj.org/article/e6171d28fbb74b748a94316bd53310fe
Autor:
Margarita A Sazonova, Andrey V Zhelankin, Valeria A Barinova, Vasily V Sinyov, Zukhra B Khasanova, Yuri V Bobryshev, Anton Y Postnov, Igor A Sobenin, Alexander N Orekhov
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
With aim of detection the spectrum of mitochondrial DNA mutations in patients with carotid atherosclerosis from Moscow Region, we used a Roche 454 high-throughput sequencing of the whole mitochondrial genome. We have found that the presence of a numb
Externí odkaz:
https://doaj.org/article/641cd436abe84094a5d1286d591ea503
Autor:
Igor A Sobenin, Margarita A Sazonova, Anton Y Postnov, Jukka T Salonen, Yuri V Bobryshev, Alexander N Orekhov
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68070 (2013)
In human pathology, several diseases are associated with somatic mutations in the mitochondrial genome (mtDNA). Even though mitochondrial dysfunction leads to increased oxidative stress, the role of mitochondrial mutations in atherosclerosis has not
Externí odkaz:
https://doaj.org/article/1a87917af3e14316893ef3385fe8c0b8
Autor:
Igor A Sobenin, Margarita A Sazonova, Maria M Ivanova, Andrey V Zhelankin, Veronika A Myasoedova, Anton Y Postnov, Serik D Nurbaev, Yuri V Bobryshev, Alexander N Orekhov
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46573 (2012)
This study was undertaken to examine the association between the level of heteroplasmy for the mutation C3256T in human white blood cells and the extent of carotid atherosclerosis, as well as the presence of coronary heart disease (CHD), the major cl
Externí odkaz:
https://doaj.org/article/ec6bc45fe49f4058aa9dc01f816828fc
Autor:
Petr V. Chumachenko, Alexandra G. Ivanova, Mariam Bagheri Ekta, Andrey V. Omelchenko, Vasily N. Sukhorukov, Alexander M. Markin, Yuliya V. Markina, Anton Y. Postnov
Publikováno v:
Journal of Clinical Medicine. 12:3578
It is known that vasa vasorum contributes substantially to the blood supply and nutrition of one-third of the wall of the ascending thoracic aorta. Therefore, we focused on studying the relationship between inflammatory cells and vasa vasorum vessels
Autor:
A.I. Ryzhkova, Alexander N. Orekhov, Margarita A. Sazonova, N.A. Doroschuk, Alexander D. Doroschuk, M.D. Sazonova, Anton Y. Postnov, Igor A. Sobenin, Victoria A. Khotina, Vasily V. Sinyov
Publikováno v:
Toxicology Reports, Vol 8, Iss, Pp 499-504 (2021)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • We studied a sample of patients with coronary heart disease. • We analyzed the telomere length in this sample. • We compared telomere length in patients and conventionally healthy study participants. • Pat
Highlights • We studied a sample of patients with coronary heart disease. • We analyzed the telomere length in this sample. • We compared telomere length in patients and conventionally healthy study participants. • Pat
Autor:
Alexander N. Orekhov, Vasily V. Sinyov, Alexander D. Doroschuk, M.D. Sazonova, Anton Y. Postnov, A.I. Ryzhkova, Igor A. Sobenin, N.A. Doroschuk, Margarita A. Sazonova
Publikováno v:
Atherosclerosis. 331:e97-e98
Publikováno v:
Atherosclerosis. 331:e103-e104
Autor:
Anton Y. Postnov, Alexander N. Orekhov, Vasily N. Sukhorukov, Alexander M Markin, Victoria A. Khotina, Y.V. Markina, M. Bagheri Ekta
Publikováno v:
European Heart Journal. 41
Background Foam cell formation caused by modified LDL is the earliest and most noticeable manifestation of atherosclerosis. The mechanisms of foam cell formation are not fully understood and can involve altered lipid uptake, impaired lipid metabolism
Autor:
Alexander N. Orekhov, Igor A. Sobenin, Vasily N. Sukhorukov, M. S. Afanasiev, Andrey V. Suslov, Mariam Bagheri Ekta, Victoria A. Khotina, Anton Y. Postnov, Peter Chumachenko, Ivan Chairkin
Publikováno v:
Current pharmaceutical design. 27(28)
Aortic aneurism development is dependent on internal and external etiological factors that define the width of the therapeutic window available for the treatment of patients with such diagnosis. In this review, we provide a detailed overview of the m