Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anton V. Zhemera"'
Autor:
Yurii S. Moroz, Anton V. Zhemera, Andrey V. Bogolyubsky, Anzhelika I. Konovets, Kateryna E. Gubina, Olena Savych, Volodymyr Brovarets, Dmytro N. Khomenko, Yuliya O. Kuchkovska, Roman Doroschuk, Sergey E. Pipko, Oleksandr O. Grygorenko, Alexander V. Grishchenko
Publikováno v:
ACS Comb Sci
Two protocols for the combinatorial synthesis of 5-(dialkylamino)tetrazoles were developed. The best success rate (67%) was shown by the method which used primary and secondary amines, 2,2,2-trifluoroethylthiocarbamate and sodium azide as the startin
Autor:
Anton V. Zhemera, Anzhelika I. Konovets, Alexander V. Grishchenko, Andrey V. Bogolubsky, Yurii V. Dmytriv, Roman Doroschuk, Yurii S. Moroz, Andrey A. Tolmachev, Pavel K. Mykhailiuk, Sergey E. Pipko, Olga A. Zaporozhets
Publikováno v:
European Journal of Organic Chemistry. 2016:2120-2130
A simple parallel synthesis approach to unsymmetrical N1,N2-substituted aliphatic oxamides using methyl (2,2,2-trifluoroethyl) oxalate and bis(2,2,2-trifluoroethyl) oxalate was developed. The method was validated on a 52-membered set of the oxamides,
Autor:
Andrey V. Bogolyubsky, Volodymyr Brovarets, Roman O. Doroshchuk, Alexander V. Grishchenko, Sergey E. Pipko, Olena Savych, Dmytro N. Khomenko, Anzhelika I. Konovets, Mykhailo Vybornyi, Anton V. Zhemera, Yurii S. Moroz
Publikováno v:
ACS combinatorial science. 20(7)
A 1,2,4-triazole motif is present in numerous commercialized and investigational bioactive molecules. Despite its importance for medicinal chemistry, there is a lack of convenient combinatorial approaches toward this molecular core. Herein, we presen
Autor:
Anton V. Zhemera, Oleksandr O. Viniychuk, Andrey V. Bogolubsky, Anzhelika I. Konovets, Pavel K. Mykhailiuk, Yurii S. Moroz, Andrey A. Tolmachev, Sergey E. Pipko, Olga A. Zaporozhets, Alexander V. Grishchenko, Dmytro V. Ushakov
Publikováno v:
ACS combinatorial science. 18(10)
One-pot synthesis of 3,5-disubstituted 1,2,4-oxadiazoles from carboxylic acids and nitriles was optimized to parallel chemistry. The method was validated on a 141 member library; the desired products were recovered with a high success rate and in mod
Autor:
Sergey E. Pipko, Yurii V. Dmytriv, Olga A. Zaporozhets, Pavel K. Mykhailiuk, Alexander V. Grishchenko, Yurii S. Moroz, Andrey V. Bogolubsky, Anton V. Zhemera, Andrey A. Tolmachev, Roman Doroschuk, Anzhelika I. Konovets
Publikováno v:
European Journal of Organic Chemistry. 2016
Autor:
Anzhelika I. Konovets, Anton V. Zhemera, Yurii S. Moroz, Olena O. Stepaniuk, Andrey A. Tolmachev, Andrey V. Bogolubsky, Pavel K. Mykhailiuk, Roman Doroschuk, Yurii V. Dmytriv, Inna S. Myronchuk, Olga A. Zaporozhets, Sergey E. Pipko
Publikováno v:
ACS combinatorial science. 17(10)
A one-pot parallel synthesis of N(1)-aryl-N(2)-alkyl-substituted oxamides with 2,2,2-trifluoroethyl chlorooxoacetate was developed. The synthesis of a library of 45 oxamides revealed higher efficiency of this reagent over the known ethyl chlorooxoace