Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Anton V. Lopuhov"'
Autor:
Anton V. Lopuhov, E. Yu. Yamansarov, Elena K. Beloglazkina, Sergei A Evteev, A. S. Olshanova, E. I. Seleznev, Alexander G. Majouga, Ya. A. Ivanenkov, Dmitry A. Skvortsov, Natalia L. Klyachko, Sergey V. Kovalev
Publikováno v:
Russian Chemical Bulletin. 69:158-163
A new promising conjugate of betulinic acid with N-acetyl-d-galactosamine was synthesized by the simple reaction sequence: esterification and copper-catalyzed azide-alkyne cycloaddition. The obtained glycoderivative exhibited high activity against he
Autor:
Yan A. Ivanenkov, Elvira T. Yamansarova, Dmitry A. Skvortsov, Sergei A Evteev, Amina Yu. Adelgareeva, Egor I. Seleznev, Alexander G. Majouga, Emil Yu. Yamansarov, Anton V. Lopuhov, Elena K. Beloglazkina, Natalia L. Klyachko, Elena V Lopatukhina
Publikováno v:
Mendeleev Communications. 29:526-528
New allobetulin conjugates were obtained through its O-esterification with hex-5-ynoic acid followed by [3+2]-cycloaddition with three azido derivatives of N-acetyl- d -galactosamine. The conjugates are non-toxic in micromolar range against hepatocel
Autor:
Elena K. Beloglazkina, Petr V. Binevski, Svetlana V. Maklakova, Yuri B. Sandulenko, Yan A. Ivanenkov, Alexander G. Majouga, Natalia Y. Galkina, Victor Koteliansky, N.L. Klyachko, Mark S. Veselov, Anton V. Lopuhov
Publikováno v:
Current drug delivery. 13(8)
During the past decade asialoglycoprotein receptor (ASGP-R) expressed predominantly by hepatocytes has attracted a considerable attention as a convenient biomolecular trap for targeted drug delivery. Currently, several selective galactose-containing