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pro vyhledávání: '"Anton V. Aseychev"'
Autor:
Olga F. Borisova, Galina E. Pozmogova, Igor P. Smirnov, Anton V. Aseychev, Anna K. Shchyolkina, Dmitry N. Kaluzhny, Anna M. Varizhuk, Edward N. Timofeev, S. L. Grokhovsky, V. L. Florentiev, Olga N. Tatarinova, Vladimir B. Tsvetkov
Publikováno v:
European Journal of Medicinal Chemistry. 67:90-97
A series of DNA aptamers bearing triazole internucleotide linkages that bind to thrombin was synthesized. The novel aptamers are structurally analogous to the well-known thrombin-inhibiting G-quadruplexes TBA15 and TBA31. The secondary structure stab