Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anton V Lopukhov"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Last decade, extracellular vesicles (EVs) attracted a lot of attention as potent versatile drug delivery vehicles. We reported earlier the development of EV-based delivery systems for therapeutic proteins and small molecule chemotherapeutics
Externí odkaz:
https://doaj.org/article/f7622b59ef5e4a1c84f9e241843437dc
Autor:
Svetlana Yu. Maklakova, Anton V. Lopukhov, Alexandr D. Khudyakov, Sergey V. Kovalev, Maria P. Mazhuga, Olga E. Chepikova, Andrey A. Zamyatnin, Alexander G. Majouga, Natalia L. Klyachko, Elena K. Beloglazkina
Publikováno v:
RSC Medicinal Chemistry. 14:56-64
Atorvastatin conjugates targeting the galactose-specific hepatic asialoglycoprotein receptor with improved stability are reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d97596c09ca6223ee6a8cecdd3856c24
https://doi.org/10.1039/d2md00119e
https://doi.org/10.1039/d2md00119e
Autor:
Ya. A. Ivanenkov, Sergey V. Kovalev, Elena K. Beloglazkina, E. Yu. Yamansarov, Natalia L. Klyachko, Nikolai V. Zyk, Rostislav A Petrov, Dmitry A. Skvortsov, Sergei A Evteev, Anton V Lopukhov, Alexander G. Majouga
Publikováno v:
Russian Chemical Bulletin. 68:2331-2338
New ligands for targeted delivery to the liver based on glycoconjugated natural triterpenoids are proposed. Simple chemical transformations of starting lupane triterpenes led to betulin or betulinic acid conjugates with N-acetyl-d-galactosamine linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e6f153ec852abc74a9c23a071b5973f
https://doi.org/10.1007/s11172-019-2707-9
https://doi.org/10.1007/s11172-019-2707-9
Autor:
Dmitry O Shkil, Petr V. Gorelkin, Alexander N. Lobov, V.A. Naumenko, Alexander Erofeev, Olga Y. Burenina, Yan A. Ivanenkov, Emil Yu. Yamansarov, Roman Akasov, Dmitry A. Skvortsov, Natalia L. Klyachko, Elena K. Beloglazkina, Sergey V. Kovalev, Alexander G. Majouga, Oxana Ryabaya, Elena V Lopatukhina, Ekaterina N Pavlova, Alexander Vaneev, Sergei A Evteev, Anton V Lopukhov
Publikováno v:
Bioconjugate chemistry. 32(4)
Herein, we describe the design, synthesis, and biological evaluation of novel betulin and N-acetyl-d-galactosamine (GalNAc) glycoconjugates and suggest them as targeted agents against hepatocellular carcinoma. We prepared six conjugates derived via t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0602f8eb7930bf89851877fd26e6ed9
https://pubmed.ncbi.nlm.nih.gov/33691403
https://pubmed.ncbi.nlm.nih.gov/33691403
Autor:
Natalia L. Klyachko, Elena V. Batrakova, Zigang Yang, Anton V Lopukhov, Marina Sokolsky-Papkov, Matthew J. Haney, Alexander V. Kabanov, Tatiana K. Bronich
Publikováno v:
Macromol Biosci
Macrophages are desirable targets for gene therapy of cancer and other diseases. Cationic diblock copolymers of polyethylene glycol (PEG) and poly-L-lysine (PLL) or poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (pAsp(DET)) are synthesized and us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeca509775400f7d8f2898e5559c862
https://europepmc.org/articles/PMC8126558/
https://europepmc.org/articles/PMC8126558/
Autor:
Olga Y. Burenina, Dmitrii A Grishin, Yan A. Ivanenkov, Sergey V. Kovalev, Yury V. Timchenko, Alexander Vaneev, Svetlana Yu. Maklakova, Alexander G. Majouga, Natalia L. Klyachko, Rostislav A Petrov, Alexander Erofeev, Elena K. Beloglazkina, Emil Yu. Yamansarov, Roman Timoshenko, Petr V. Gorelkin, Elena V Lopatukhina, Evgenia E Ondar, Sergei A Evteev, Anton V Lopukhov, Sofiia R Mefedova
Publikováno v:
Molecular pharmaceutics. 18(1)
In this work, we have developed covalent and low molecular weight docetaxel delivery systems based on conjugation with N-acetyl-d-galactosamine and studied their properties related to hepatocellular carcinoma cells. The resulting glycoconjugates have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e137e7aecf403164e00f990463563d82
https://pubmed.ncbi.nlm.nih.gov/33264010
https://pubmed.ncbi.nlm.nih.gov/33264010
Autor:
Alexander N. Lobov, Natalia L. Klyachko, Olga Y. Burenina, Ivan V Kislyakov, Yan A. Ivanenkov, Galina S Reshitko, Sergey V. Kovalev, Elena K. Beloglazkina, Irina V. Saltykova, Alexander Erofeev, Dmitry O Shkil, Emil Yu. Yamansarov, Elena V Lopatukhina, Peter Gorelkin, Anastasiia S Garanina, Olga A. Dontsova, Alexander G. Majouga, Sergei A Evteev, Anton V Lopukhov
Publikováno v:
Bioconjugate chemistry. 31(5)
Since the asialoglycoprotein receptor (also known as the "Ashwell-Morell receptor" or ASGPR) was discovered as the first cellular mammalian lectin, numerous drug delivery systems have been developed and several gene delivery systems associated with m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a0036c9314579988adf7544e1bf3c5
https://pubmed.ncbi.nlm.nih.gov/32379426
https://pubmed.ncbi.nlm.nih.gov/32379426