Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anton Sinitskiy"'
Autor:
Emma King-Smith, Felix Faber, Usa Reilly, Anton Sinitskiy, Qingyi Yang, Bo Liu, Dennis Hyek, Alpha Lee
Structural diversification of lead molecules is a key component of drug discovery to explore chemical space. Late stage functionalizations (LSFs) are versatile methodologies capable of installing functional handles on richly decorated intermediates t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3dec14f4b80ad9edd74d1765f524d38
https://doi.org/10.21203/rs.3.rs-2741247/v1
https://doi.org/10.21203/rs.3.rs-2741247/v1
Meaningful exploration of the chemical space of druglike molecules in drug design is a highly challenging task due to a combinatorial explosion of possible modifications of molecules. In this work, we address this problem with transformer models, a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08c3dbb1d3d29d07ac4e7b71f1429b06
https://doi.org/10.26434/chemrxiv-2022-gln27
https://doi.org/10.26434/chemrxiv-2022-gln27
Transformation of C-H to C-F bonds in organic compounds can be used in drug design to easily diversify molecular series under exploration. A particularly attractive fluorination reaction is the recently discovered aliphatic C-H bonds fluorination cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e57fd8989b202f0031b1306d2e2765a7
https://doi.org/10.26434/chemrxiv-2022-2vtzg
https://doi.org/10.26434/chemrxiv-2022-2vtzg
Autor:
Olga Saeva, N. V. Yurkevich, Yaroslav K. Kamnev, Anton Sinitskiy, Aleksandr Shein, Nataliya Yurkevich
Publikováno v:
Interexpo GEO-Siberia. 2:129-136
This paper presents the chemical and mineral composition of the soil core of the Gydan Peninsula near the Parisento Lake. The changes in the K, Ca, Mn, Fe, Ti, Cu, Pb, Br, As concentrations over the core depth depending on its structure, mineralogica
Publikováno v:
Interexpo GEO-Siberia. 2:103-110
The article presents the results of studies of freezing talik under lake with using of electrical resistivity tomography. The research was conducted on one of paleolake – khasyrey. The measurements performed in two perpendicular profiles by pole-di
Publikováno v:
26th International Symposium on Atmospheric and Ocean Optics, Atmospheric Physics.
The department traditionally holds specialized practices of cryolithology and glaciology. Recently, specialized field course (sometimes international) have been concentrated in the Arctic region of Russia in the south of Yamal. The studies were focus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1225af301a6d7ec39df2271b03097d5b
https://doi.org/10.5194/egusphere-egu2020-17896
https://doi.org/10.5194/egusphere-egu2020-17896