N-Azidoacetylmannosamine-mediated chemical tagging of gangliosides

Autor: Anton P. Bussink, Paul F. van Swieten, Karen Ghauharali, Saskia Scheij, Marco van Eijk, Tom Wennekes, Gijs A. van der Marel, Rolf G. Boot, Johannes M.F.G. Aerts, Herman S. Overkleeft

Publikováno v: Journal of Lipid Research, Vol 48, Iss 6, Pp 1417-1421 (2007)

Peracetylated N-α-azidoacetylmannosamine (Ac4ManNAz) is metabolized by cells to CMP-azidosialic acid. It has been demonstrated previously that in this way azidosialic acid-containing glycoproteins are formed that can be labeled on the cell surface b

Externí odkaz: https://doaj.org/article/66c6502612744bc7b882a6938d45887c

Suboptimal Viral Suppression Rates Among HIV-Infected Children in Low- and Middle-Income Countries: A Meta-analysis

Autor: Tobias F. Rinke de Wit, T. Sonia Boender, Michael Boele van Hensbroek, Ragna S. Boerma, Kim C.E. Sigaloff, Anton P. Bussink, Silvia Bertagnolio, Job C. J. Calis

Publikováno v: Boerma, R S, Boender, T S, Bussink, A P, Calis, J C J, Bertagnolio, S, Rinke de Wit, T F, Boele van Hensbroek, M & Sigaloff, K C E 2016, ' Suboptimal Viral Suppression Rates Among HIV-Infected Children in Low-and Middle-Income Countries : A Meta-analysis ', Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol. 63, no. 12, pp. 1645-1654 . https://doi.org/10.1093/cid/ciw645
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 63(12), 1645-1654
Clinical infectious diseases, 63(12), 1645-1654. Oxford University Press

BACKGROUND: The 90-90-90 goal to achieve viral suppression in 90% of all human immunodeficiency virus (HIV)-infected people on antiretroviral treatment (ART) is especially challenging in children. Global estimates of viral suppression among children

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e00aa7d6055789ba7cd2dd50f31add
https://pubmed.ncbi.nlm.nih.gov/27660236

Evolution of Mammalian Chitinase(-Like) Members of Family 18 Glycosyl Hydrolases

Autor: Anton P. Bussink, Johannes M. F. G. Aerts, Dave Speijer, Rolf G. Boot

Publikováno v: Genetics, 177(2), 959-970. Genetics Society of America

Family 18 of glycosyl hydrolases encompasses chitinases and so-called chi-lectins lacking enzymatic activity due to amino acid substitutions in their active site. Both types of proteins widely occur in mammals although these organisms lack endogenous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a0df77d41b69ae182582ada3544034
https://doi.org/10.1534/genetics.107.075846

The biology of the Gaucher cell: the cradle of human chitinases

Autor: G. Herma Renkema, Anton P. Bussink, Rolf G. Boot, Johannes M. F. G. Aerts, Marco van Eijk

Publikováno v: International Review of Cytology ISBN: 9780123646569

Gaucher disease (GD) is the most common lysosomal storage disorder and is caused by inherited deficiencies of glucocerebrosidase, the enzyme responsible for the lysosomal breakdown of the lipid glucosylceramide. GD is characterized by the accumulatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91cd438701ac472ed83d28aae600db5
https://doi.org/10.1016/s0074-7696(06)52001-7

Pancreatic-type ribonuclease 1 gene duplications in rat species

Autor: François Catzeflis, Patty Mulder, Peter A. Jekel, Jaap J. Beintema, Anton P. Bussink, Jean-Yves F. Dubois, Antonella Carsana

Publikováno v: Journal of Molecular Evolution, 55(5), 522-533. Springer Verlag

Mammalian pancreatic-type ribonucleases (RNases) 1 represent single-copy genes in the genome of most investigated mammalian species, including Mus musculus and other murid rodents. However, in six species belonging to the genus Rattus and closely rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c1aa399f3fa67fd629d13bacd5ba65
https://doi.org/10.1007/s00239-002-2347-8