Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Anton Matafonov"'
Autor:
Charles E Bane, Ivan Ivanov, Anton Matafonov, Kelli L Boyd, Qiufang Cheng, Edward R Sherwood, Erik I Tucker, Stephen T Smiley, Owen J T McCarty, Andras Gruber, David Gailani
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152968 (2016)
Sepsis, a systemic inflammatory response to infection, is often accompanied by abnormalities of blood coagulation. Prior work with a mouse model of sepsis induced by cecal ligation and puncture (CLP) suggested that the protease factor XIa contributed
Externí odkaz:
https://doaj.org/article/15e4234e34084d13b6001a61916bc58a
Autor:
Keiko Takahashi, Anton Matafonov, Katherine Sumarriva, Hideyuki Ito, Colette Lauhan, Dana Zemel, Nobuo Tsuboi, Jin Chen, Albert Reynolds, Takamune Takahashi
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112753 (2014)
CD148 is a transmembrane tyrosine phosphatase that is expressed at cell junctions. Recent studies have shown that CD148 associates with the cadherin/catenin complex and p120 catenin (p120) may serve as a substrate. However, the role of CD148 in cadhe
Externí odkaz:
https://doaj.org/article/ec49b215f0de41a1a911437864f87a2f
Autor:
Maxim Litvak, Aleksandr Shamanaev, Sandip Zalawadiya, Anton Matafonov, Anton Kobrin, Edward P. Feener, Michael Wallisch, Erik I. Tucker, Owen J.T. McCarty, David Gailani
Publikováno v:
Journal of Thrombosis and Haemostasis. 21:1200-1213
Autor:
Qiufang Cheng, Bassem M Mohammed, David Gailani, Anton Matafonov, Mao-fu Sun, Ingrid M. Verhamme, Kusumam Joseph, Allen P. Kaplan, Ivan B. Ivanov, S. Kent Dickeson
Publikováno v:
Blood. 135:558-567
Prekallikrein (PK) is the precursor of the trypsin-like plasma protease kallikrein (PKa), which cleaves kininogens to release bradykinin and converts the protease precursor factor XII (FXII) to the enzyme FXIIa. PK and FXII undergo reciprocal convers
Autor:
Bassem M. Mohammed, Dougald M. Monroe, Qiufang Cheng, Anton Matafonov, David Gailani, Joost C. M. Meijers
Publikováno v:
Journal of thrombosis and haemostasis, 16(10), 2044-2049. Wiley-Blackwell
Essentials Mice lacking factor IX (FIX) or factor XI (FXI) were tested in a saphenous vein bleeding model. FIX-deficient mice displayed a hemostatic defect and FXI-deficient mice were similar to wild type mice. Infusion of FXI or over-expression of F
Publikováno v:
Research and Practice in Thrombosis and Haemostasis
Essentials Conversion of FXII to α‐FXIIa on surfaces requires cleavage after Arginine 353.Replacing Arg353 with alanine results in a single chain form (FXII‐R353A) that has some activity.Replacing Arg‐353 with proline (FXII‐Locarno, FXII‐R
Autor:
Anton Matafonov, Igor Feoktistov, Truc-Linh Tran, Cristi L. Galindo, Qinkun Zhang, Carrie Geisberg Lenneman, Douglas B. Sawyer, Daniel J. Lenihan, Sergey Ryzhov
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 312:H907-H918
Immune activation in chronic systolic heart failure (HF) correlates with disease severity and prognosis. Recombinant neuregulin-1 (rNRG-1) is being developed as a possible therapy for HF, based on the activation of ERBB receptors in cardiac cells. Wo
Autor:
Ana Serezani, Timothy S. Blackwell, Georgii Vasiukov, Vasiliy V. Polosukhin, Sergey Gutor, Anton Matafonov, Wei Han, Rinat Zaynagetdinov, Sergey V. Novitskiy, Linda A. Gleaves, Taylor P. Sherrill
Publikováno v:
Oncotarget
Growth arrest-specific 6 (Gas6) has been implicated in carcinogenesis through activation of its receptors, particularly MerTK. To investigate whether Gas6 plays a role in resistance to NF-κB inhibitors, which have not proven to be effective agents f
Autor:
David Gailani, Shauna Mason, Daniel J. Sexton, Ivan B. Ivanov, Thomas Renné, Yasin Kokoye, Edward P. Feener, Anton Matafonov, Keith R. McCrae, Qiufang Cheng, S. Kent Dickeson
Publikováno v:
Thrombosis Research. 140:118-124
Studies with animal models implicate the plasma proteases factor XIIa (FXIIa) and α-kallikrein in arterial and venous thrombosis. As congenital deficiencies of factor XII (FXII) or prekallikrein (PK), the zymogens of FXIIa and α-kallikrein respecti
Autor:
Tarek S. Absi, Niki L Fortune, Daniel T. Matthews, James West, Anna R. Hemnes, Eric D. Austin, Yan Ru Su, David Gailani, Stephen J. Halliday, M. Talati, Anton Matafonov
Publikováno v:
JRSM Cardiovascular Disease, Vol 9 (2020)
JRSM Cardiovascular Disease
JRSM Cardiovascular Disease
Purpose Chronic thromboembolic pulmonary hypertension is characterized by incomplete thrombus resolution following acute pulmonary embolism, leading to pulmonary hypertension and right ventricular dysfunction. Conditions such as thrombophilias, dysfi