Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Anton M. Bennett"'
Autor:
Bin Qiu, Ahmed Lawan, Chrysovalantou E. Xirouchaki, Jae-Sung Yi, Marie Robert, Lei Zhang, Wendy Brown, Carlos Fernández-Hernando, Xiaoyong Yang, Tony Tiganis, Anton M. Bennett
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Nonalcoholic steatohepatitis (NASH) is triggered by hepatocyte death through activation of caspase 6, as a result of decreased adenosine monophosphate (AMP)-activated protein kinase-alpha (AMPKα) activity. Increased hepatocellular death pro
Externí odkaz:
https://doaj.org/article/7f0cbbbde00c4636bef5fd1be82a4956
Autor:
Theodoros Karampitsakos, Apostolos Galaris, Ilianna Barbayianni, Giuseppe DeIuliis, Farida Ahangari, Fotis Sampsonas, Vasilina Sotiropoulou, Vassilis Aidinis, Anton M. Bennett, Jose D. Herazo-Maya, Nikolaos Xylourgidis, Petros Bakakos, Demosthenes Bouros, Naftali Kaminski, Argyrios Tzouvelekis
Publikováno v:
Diagnostics, Vol 13, Iss 6, p 1166 (2023)
Background: We have previously shown that SHP2 downregulation may predispose fibroblasts to differentiate into myofibroblasts and proposed a role for SHP2 downregulation in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Recent data have sho
Externí odkaz:
https://doaj.org/article/02774861c2644bee8c0e2beff5b819c2
Autor:
Xinbo Zhang, Zhiqiang Zhao, Margaret Baldini, Cheng Zhang, Bo Tao, Lei Zhang, Anton M. Bennett, Jun Yu
Publikováno v:
JVS - Vascular Science, Vol 3, Iss , Pp 423- (2022)
Externí odkaz:
https://doaj.org/article/64e345d81d6e45a38d821d064d0cf005
Autor:
Chao Zhong, Kisuk Min, Zhiqiang Zhao, Cheng Zhang, Erhe Gao, Yan Huang, Xinbo Zhang, Margaret Baldini, Rajika Roy, Xiaofeng Yang, Walter J. Koch, Anton M. Bennett, Jun Yu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cardiac fibrosis, a pathological condition due to excessive extracellular matrix (ECM) deposition in the myocardium, is associated with nearly all forms of heart disease. The processes and mechanisms that regulate cardiac fibrosis are not fully under
Externí odkaz:
https://doaj.org/article/4f0f02c0a7a241859176ace2d6dc8885
Autor:
Aaron D. Levy, Xiao Xiao, Juliana E. Shaw, Suma Priya Sudarsana Devi, Sara Marie Katrancha, Anton M. Bennett, Charles A. Greer, James R. Howe, Kazuya Machida, Anthony J. Koleske
Publikováno v:
Cell Reports, Vol 24, Iss 6, Pp 1523-1535 (2018)
Summary: Hyperactivating mutations in the non-receptor tyrosine phosphatase SHP2 cause Noonan syndrome (NS). NS is associated with cognitive deficits, but how hyperactivation of SHP2 in NS changes neuron function is not well understood. We find that
Externí odkaz:
https://doaj.org/article/2fcf40d6c87c43689141ac463046f066
Publikováno v:
Skeletal Muscle, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Background The mitogen-activated protein kinases (MAPKs) have been shown to be involved in regulating myofiber survival. In skeletal muscle, p38 MAPK and JNK are negatively regulated by MAPK phosphatase-5 (MKP-5). During muscle regeneration,
Externí odkaz:
https://doaj.org/article/36ab4de4182445a79c4ca37ca92a748e
Publikováno v:
Annual Review of Pharmacology and Toxicology. 63:617-636
Phosphatases and kinases maintain an equilibrium of dephosphorylated and phosphorylated proteins, respectively, that are required for critical cellular functions. Imbalance in this equilibrium or irregularity in their function causes unfavorable cell
Autor:
Pablo Fernández-Tussy, Jonathan Sun, Magdalena P. Cardelo, Nathan L. Price, Leigh Goedeke, Chrysovalantou E. Xirouchaki, Xiaoyong Yang, Oscar Pastor-Rojo, Anton M. Bennett, Tony Tiganis, Yajaira Suárez, Carlos Fernández-Hernando
Publikováno v:
bioRxiv
The complexity of the multiple mechanisms underlying non-alcoholic fatty liver disease (NAFLD) progression remains a significant challenge for the development of effective therapeutics. miRNAs have shown great promise as regulators of biological proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a685c6a02c0c1eb0bf66953c653aed
https://europepmc.org/articles/PMC9882318/
https://europepmc.org/articles/PMC9882318/
Autor:
Anton M. Bennett
Publikováno v:
Journal of Biological Chemistry. 299:104731
Autor:
Maria I. Kontaridis, Amy E. Roberts, Lisa Schill, Lisa Schoyer, Beth Stronach, Gregor Andelfinger, Yoko Aoki, Marni E. Axelrad, Annette Bakker, Anton M. Bennett, Alberto Broniscer, Pau Castel, Caitlin A. Chang, Lukas Cyganek, Tirtha K. Das, Jeroen Hertog, Emilia Galperin, Shruti Garg, Bruce D. Gelb, Kristiana Gordon, Tamar Green, Karen W. Gripp, Maxim Itkin, Maija Kiuru, Bruce R. Korf, Jeff R. Livingstone, Alejandro López‐Juárez, Pilar L. Magoulas, Sahar Mansour, Theresa Milner, Elisabeth Parker, Elizabeth I. Pierpont, Kevin Plouffe, Katherine A. Rauen, Suma P. Shankar, Shane B. Smith, David A. Stevenson, Marco Tartaglia, Richard Van, Morgan E. Wagner, Stephanie M. Ware, Martin Zenker
Publikováno v:
American journal of medical genetics. Part A, vol 188, iss 6
Kontaridis, M I, Roberts, A E, Schill, L, Schoyer, L, Stronach, B, Andelfinger, G, Aoki, Y, Axelrad, M E, Bakker, A, Bennett, A M, Broniscer, A, Castel, P, Chang, C A, Cyganek, L, Das, T K, den Hertog, J, Galperin, E, Garg, S, Gelb, B D, Gordon, K, Green, T, Gripp, K W, Itkin, M, Kiuru, M, Korf, B R, Livingstone, J R, López-Juárez, A, Magoulas, P L, Mansour, S, Milner, T, Parker, E, Pierpont, E I, Plouffe, K, Rauen, K A, Shankar, S P, Smith, S B, Stevenson, D A, Tartaglia, M, Van, R, Wagner, M E, Ware, S M & Zenker, M 2022, ' The seventh international RASopathies symposium : Pathways to a cure-expanding knowledge, enhancing research, and therapeutic discovery ', American Journal of Medical Genetics. Part A . https://doi.org/10.1002/ajmg.a.62716
American Journal of Medical Genetics, Part A, 188(6), 1915-1927. Wiley-Liss Inc.
Kontaridis, M I, Roberts, A E, Schill, L, Schoyer, L, Stronach, B, Andelfinger, G, Aoki, Y, Axelrad, M E, Bakker, A, Bennett, A M, Broniscer, A, Castel, P, Chang, C A, Cyganek, L, Das, T K, den Hertog, J, Galperin, E, Garg, S, Gelb, B D, Gordon, K, Green, T, Gripp, K W, Itkin, M, Kiuru, M, Korf, B R, Livingstone, J R, López-Juárez, A, Magoulas, P L, Mansour, S, Milner, T, Parker, E, Pierpont, E I, Plouffe, K, Rauen, K A, Shankar, S P, Smith, S B, Stevenson, D A, Tartaglia, M, Van, R, Wagner, M E, Ware, S M & Zenker, M 2022, ' The seventh international RASopathies symposium : Pathways to a cure-expanding knowledge, enhancing research, and therapeutic discovery ', American Journal of Medical Genetics. Part A . https://doi.org/10.1002/ajmg.a.62716
American Journal of Medical Genetics, Part A, 188(6), 1915-1927. Wiley-Liss Inc.
RASopathies are a group of genetic disorders that are caused by genes that affect the canonical Ras/mitogen-activated protein kinase (MAPK) signaling pathway. Despite tremendous progress in understanding the molecular consequences of these genetic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66770a599b697c0d77d007bd425f8e74
https://escholarship.org/uc/item/44s997fh
https://escholarship.org/uc/item/44s997fh