Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Anton M Sholukh"'
Autor:
Anton M Sholukh, Muhammad M Mukhtar, Michael Humbert, Sosthène S Essono, Jennifer D Watkins, Hemant K Vyas, Vivekanandan Shanmuganathan, Girish Hemashettar, Maria Kahn, Shiu-Lok Hu, David C Montefiori, Victoria R Polonis, Peter H Schur, Ruth M Ruprecht
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38943 (2012)
Existing technologies allow isolating antigen-specific monoclonal antibodies (mAbs) from B cells. We devised a direct approach to isolate mAbs with predetermined conformational epitope specificity, using epitope mimetics (mimotopes) that reflect the
Externí odkaz:
https://doaj.org/article/a1ec615739fa408abdc9fe5924127437
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107527- (2023)
Summary: Because virus neutralization cannot solely explain vaccine-induced, antibody-mediated protection, antibody effector functions are being considered as a potential correlate of protection (CoP). However, measuring effector functions at a fixed
Externí odkaz:
https://doaj.org/article/89ca062fe2c84b678c418ecc6e243bb1
Autor:
Sebastian Fiedler, Sean R. A. Devenish, Alexey S. Morgunov, Alison Ilsley, Francesco Ricci, Marc Emmenegger, Vasilis Kosmoliaptsis, Elitza S. Theel, John R. Mills, Anton M. Sholukh, Adriano Aguzzi, Akiko Iwasaki, Andrew K. Lynn, Tuomas P. J. Knowles
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The effectiveness of therapeutic monoclonal antibodies (mAbs) against variants of the SARS-CoV-2 virus is highly variable. As target recognition of mAbs relies on tight binding affinity, we assessed the affinities of five therapeutic mAbs to
Externí odkaz:
https://doaj.org/article/37ab6ec638ee406db7b4169cab17fda0
Autor:
Nicholas K. Hurlburt, Leah J. Homad, Irika Sinha, Madeleine F. Jennewein, Anna J. MacCamy, Yu-Hsin Wan, Jim Boonyaratanakornkit, Anton M. Sholukh, Abigail M. Jackson, Panpan Zhou, Dennis R. Burton, Raiees Andrabi, Gabriel Ozorowski, Andrew B. Ward, Leonidas Stamatatos, Marie Pancera, Andrew T. McGuire
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Structural and functional characterisation of an antibody CV3-25 reveals wide neutralisation spectrum of the antibody against multiple SARS-CoV2 variants.
Externí odkaz:
https://doaj.org/article/9ae2f5da8740455aa2d1d7b54d5933e4
Autor:
Andres Chang, Anton M. Sholukh, Andreas Wieland, David L. Jaye, Mary Carrington, Meei-Li Huang, Hong Xie, Keith R. Jerome, Pavitra Roychoudhury, Alexander L. Greninger, Jean L. Koff, Jonathon B. Cohen, David M. Koelle, Lawrence Corey, Christopher R. Flowers, Rafi Ahmed
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 18 (2022)
Background Herpes simplex virus lymphadenitis (HSVL) is an unusual presentation of HSV reactivation in patients with chronic lymphocytic leukemia (CLL) and is characterized by systemic symptoms and no herpetic lesions. The immune responses during HSV
Externí odkaz:
https://doaj.org/article/b553259f84e34b31aaacb3c20315e95c
Autor:
Jim Boonyaratanakornkit, Anton M. Sholukh, Matthew Gray, Emily L. Bossard, Emily S. Ford, Kizzmekia S. Corbett, Lawrence Corey, Justin J. Taylor
Publikováno v:
Viruses, Vol 13, Iss 10, p 2075 (2021)
The human Betacoronavirus OC43 is a common cause of respiratory viral infections in adults and children. Lung infections with OC43 are associated with mortality, especially in hematopoietic stem cell transplant recipients. Neutralizing antibodies pla
Externí odkaz:
https://doaj.org/article/6b7e086a7deb4ab0b24fa10940af3282
Autor:
Emily S. Ford, Koshlan Mayer-Blackwell, Lichen Jing, Anton M. Sholukh, Russell St. Germain, Emily L. Bossard, Hong Xie, Thomas H. Pulliam, Saumya Jani, Stacy Selke, Carlissa J. Burrow, Christopher L. McClurkan, Anna Wald, Michael R. Holbrook, Brett Eaton, Elizabeth Eudy, Michael Murphy, Elena Postnikova, Harlan S. Robins, Rebecca Elyanow, Rachel M. Gittelman, Matyas Ecsedi, Elise Wilcox, Aude G. Chapuis, Andrew Fiore-Gartland, David M. Koelle
Almost three years into the SARS-CoV-2 pandemic, hybrid immunity is highly prevalent worldwide and more protective than vaccination or prior infection alone. Given emerging resistance of variant strains to neutralizing antibodies (nAb), it is likely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7289f7cc61349935427f6be13b556e0e
https://doi.org/10.21203/rs.3.rs-2146712/v1
https://doi.org/10.21203/rs.3.rs-2146712/v1
Publikováno v:
SSRN Electronic Journal.
Autor:
Panpan Zhou, Raiees Andrabi, Madeleine F Jenewein, Anton M Sholukh, Leonidas Stamatatos, Jim Boonyaratanakornkit, Leah J. Homad, Dennis R. Burton, Anna J. MacCamy, Nicholas K. Hurlburt, Yu-Hsin Wan, Andrew T. McGuire, Irika Siha, Marie Pancera
Three highly pathogenic betacoronaviruses have crossed the species barrier and established human-to-human transmission causing significant morbidity and mortality in the past 20 years. The most current and widespread of these is SARS-CoV-2. The ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5e191bd06ef3161bfcc42e2ba89ce80
https://doi.org/10.1101/2021.08.02.454829
https://doi.org/10.1101/2021.08.02.454829
Autor:
Peter B. Rupert, Meei-Li Huang, Haiying Zhu, Andrew Fiore-Gartland, Arnold Park, Colleen McLaughlin, Chance Brock, April K. Randhawa, Roland K. Strong, Maurine D. Miner, Yixuan J. Hou, Matthew Buerger, Ralph S. Baric, Emily S Ford, Leonidas Stamatatos, Anton M Sholukh, Hannah Kaiser, Russell St Germain, Florian A. Lempp, Keith R. Jerome, Andrew B. Stuart, Joyce Y C Lu, Emily L Bossard, Bhanupriya Madarampalli, Margaret K. Doll, Jia Jin Kee, Kurt Diem, Lawrence Corey, Longping V. Tse, David C. Montefiori
Publikováno v:
Journal of Clinical Microbiology
Determinants of protective immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection require the development of well-standardized, reproducible antibody assays. This need has led to the emergence of a variety of neutrali