TWEAK Receptor Deficiency Has Opposite Effects on Female and Male Mice Subjected to Neonatal Hypoxia–Ischemia

Autor: Anton Kichev, Ana A. Baburamani, Regina Vontell, Pierre Gressens, Linda Burkly, Claire Thornton, Henrik Hagberg

Publikováno v: Frontiers in Neurology, Vol 9 (2018)

Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) is a multifunctional cytokine member of the TNF family. TWEAK binds to its only known receptor, Fn14, enabling it to activate downstream signaling processes in response to tissue inju

Externí odkaz: https://doaj.org/article/62a4098eec1c4f3fa55364f625d9a144

Oxidative stress and endoplasmic reticulum (ER) stress in the development of neonatal hypoxic-ischaemic brain injury

Autor: Claire Thornton, Henrik Hagberg, Anton Kichev, Ana A. Baburamani

Publikováno v: Thornton, C, Baburamani, A, Kichev, A & Hagberg, H 2017, ' Oxidative stress and endoplasmic reticulum (ER) stress in the development of neonatal hypoxic-ischaemic brain injury. ', Biochemical Society Transactions, vol. 45, no. 5, pp. 1067-1076 . https://doi.org/10.1042/BST20170017
Biochemical Society Transactions

Birth asphyxia in term neonates affects 1–2/1000 live births and results in the development of hypoxic–ischaemic encephalopathy with devastating life-long consequences. The majority of neuronal cell death occurs with a delay, providing the potent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3af238c50a69666d3fad19fe3879991
https://kclpure.kcl.ac.uk/ws/files/84278699/Oxidative_stress_and_endoplasmic_THORNTON_Publishedonline22September2017_GOLD_VoR_CC_BY_.pdf

Implicating Receptor Activator of NF-κB (RANK)/RANK Ligand Signalling in Microglial Responses to Toll-Like Receptor Stimuli

Autor: Anton, Kichev, Pascale, Eede, Pierre, Gressens, Claire, Thornton, Henrik, Hagberg

Publikováno v: Developmental neuroscience. 39(1-4)

Inflammation in the perinatal brain caused by maternal or intrauterine fetal infection is now well established as an important contributor to the development of perinatal brain injury. Exposure to inflammatory products can impair perinatal brain deve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::002c1997e92509461ffcfb440fc7940f
https://pubmed.ncbi.nlm.nih.gov/28402971

Pro-NGF from Alzheimer's Disease and Normal Human Brain Displays Distinctive Abilities to Induce Processing and Nuclear Translocation of Intracellular Domain of p75NTR and Apoptosis

Autor: Jordi Saurat, Begoña Perez, Isidre Ferrer, Petar Podlesniy, Mario Encinas, Carlos E. Pedraza, Anton Kichev, Carme Espinet

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Repositorio Abierto de la UdL
Universitad de Lleida

The pro form of neurotrophic growth factor (pro-NGF), purified by chromatography from human Alzheimer’s disease (AD)-affected brains (ADhbi-pro-NGF), has been shown to induce apoptotic cell death in neuronal cell cultures through its interaction wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8435ecf378bad3c58e6561280ef62a21
https://doi.org/10.2353/ajpath.2006.050787

A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice

Autor: Catherine I, Rousset, Fiona C, Leiper, Anton, Kichev, Pierre, Gressens, David, Carling, Henrik, Hagberg, Claire, Thornton

Publikováno v: Journal of Neurochemistry

Perinatal hypoxic–ischaemic encephalopathy (HIE) occurs in 1–2 in every 1000 term infants and the devastating consequences range from cerebral palsy, epilepsy and neurological deficit to death. Cellular damage post insult occurs after a delay and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91a6e15703a8f80035897cccebdc91e3
https://pubmed.ncbi.nlm.nih.gov/25598140