Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Anton H. N. Hopman"'
Autor:
Stefan G. C. Mestrum, Norbert C. J. de Wit, Eline M. P. Cremers, Roosmarie J. M. Drent, Frans C. S. Ramaekers, Anton H. N. Hopman, Math P. G. Leers
Publikováno v:
HemaSphere, Vol 6, Iss 12, p e804 (2022)
Externí odkaz:
https://doaj.org/article/b9e57974a5ba4b56be736fd375b52052
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0297008 (2024)
Methylation and hydroxymethylation of cytosine moieties in CpG islands of specific genes are epigenetic processes shown to be involved in the development of cervical (pre)neoplastic lesions. We studied global (hydroxy)methylation during the subsequen
Externí odkaz:
https://doaj.org/article/e0f64a838b884ead8dc65e263fb9329a
Autor:
Jobran M. Moshi, Monique Ummelen, Jos L. V. Broers, Frans C. S. Ramaekers, Anton H. N. Hopman
Publikováno v:
Histochemistry and Cell Biology. Springer Verlag
This study compares three different pretreatment protocols for the immunohistochemical detection of 5-methylcytosine (5-mC) and 5-hydroxymethylcytosine (5-hmC) in nuclear DNA. The human biological samples analyzed included formalin-fixed and paraffin
Autor:
Jobran M. Moshi, Monique Ummelen, Jos L. V. Broers, Frank Smedts, Koen K. Van de Vijver, Jack P. M. Cleutjens, Rogier J. N. T. M. Litjens, Frans C. S. Ramaekers, Anton H. N. Hopman
Publikováno v:
Histochemistry and Cell Biology, 158(6), 545-559. Springer Verlag
SOX2 expression in high-grade cervical intraepithelial neoplasia (CIN3) and cervical squamous cell carcinoma is increased compared to that in the normal cervical epithelium. However, data on the expression and histological distribution of SOX2 in squ
Autor:
Stefan G. C. Mestrum, Roanalis B. Y. Vanblarcum, Roosmarie J. M. Drent, Bert T. Boonen, Wouter L. W. van Hemert, Frans C. S. Ramaekers, Anton H. N. Hopman, Math P. G. Leers
Publikováno v:
Cytometry Part A, 101(7), 552-563. Wiley
Recent developments in clinical flow cytometry allow the simultaneous assessment of proliferative and anti-apoptotic activity in the different hematopoietic cell lineages and during their maturation process. This can further advance the flow cytometr
The aim of this study was to compare three different pretreatment protocols for the detection of 5-methylcytosine (5-mC) and 5-hydroxymethylcytosine (5-hmC) in nuclear DNA. Several types of human biological samples were analyzed, including formalin f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e984edfa39b547ff8320be90954a9531
https://doi.org/10.21203/rs.3.rs-2234522/v1
https://doi.org/10.21203/rs.3.rs-2234522/v1
Publikováno v:
Blood Adv
Standardization of the detection and quantification of leukocyte differentiation markers by the EuroFlow Consortium has led to a major step forward in the integration of flow cytometry into classification of leukemia and lymphoma. In our opinion, thi
Autor:
Roosmarie J. M. Drent, Stefan G. C. Mestrum, Norbert C. J. de Wit, Math P. G. Leers, Anton H. N. Hopman, Frans C. S. Ramaekers
Publikováno v:
Cytometry Part B: Clinical Cytometry. 100:322-330
The proliferation marker Ki-67 is widely used within the field of diagnostic histopathology as a prognostic marker for solid cancers. However, Ki-67 is hardly used for prognostic and diagnostic purposes in flow cytometric analyses of hematologic neop
Autor:
Stefan G C, Mestrum, Norbert C J, de Wit, Roosmarie J M, Drent, Anton H N, Hopman, Frans C S, Ramaekers, Math P G, Leers
Publikováno v:
Cytometry. Part B, Clinical Cytometry
The proliferation marker Ki‐67 is widely used within the field of diagnostic histopathology as a prognostic marker for solid cancers. However, Ki‐67 is hardly used for prognostic and diagnostic purposes in flow cytometric analyses of hematologic
Autor:
Irene T Øvestad, Roy F.P.M. Kruitwagen, Arnold J. Kruse, Monique Ummelen, Margot M. Koeneman, Emiel A. M. Janssen, Anton H. N. Hopman
Publikováno v:
Pathology Oncology Research
Pathology & oncology Research, 25(2), 549-557. Springer, Cham
Pathology & oncology Research, 25(2), 549-557. Springer, Cham
Approximately 20-40% of high-grade Cervical Intraepithelial Neoplasia (CIN) regresses spontaneously, but the natural prognosis of an individual lesion is unpredictable. Gain of the chromosomal 3q region, which contains the human telomerase RNA gene o