Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Anton Goussev"'
Autor:
Changsheng Qu, Ruizhuo Ning, Anton Goussev, Asim Mahmood, David L. Kaplan, Ye Xiong, Michael Chopp
Publikováno v:
Journal of Neurosurgery. 111:658-665
Object This study was designed to investigate new ways of delivering human marrow stromal cells (hMSCs) to the injured brain by impregnating them into collagen scaffolds in a mouse model of traumatic brain injury (TBI). Methods Eight C57BL/6 J mice w
Autor:
Anton Goussev, Ye Xiong, Dunyue Lu, Changsheng Qu, Asim Mahmood, Constance Tom Noguchi, Zheng Gang Zhang, Timothy J Schallert, Michael Chopp, Humaira Kazmi
Publikováno v:
Brain Research. 1230:247-257
Erythropoietin (EPO) and its receptor (EPOR), essential for erythropoiesis, are expressed in the nervous system. Recombinant human EPO treatment promotes functional outcome after traumatic brain injury (TBI) and stroke, suggesting that the endogenous
Autor:
Ye Xiong, Changsheng Qu, Timothy J Schallert, Anton Goussev, Dunyue Lu, Asim Mahmood, Michael Chopp
Publikováno v:
Journal of Neurosurgery. 109:510-521
Object This study was designed to investigate the beneficial effects of recombinant human erythropoietin (rhEPO) treatment of traumatic brain injury (TBI) in mice. Methods Adult male C57BL/6 mice were divided into 3 groups: 1) the saline group (TBI a
Autor:
Asim Mahmood, Anton Goussev, Dunyue Lu, Changsheng Qu, Timothy J Schallert, Michael Chopp, Ye Xiong
Publikováno v:
Brain Research. 1185:301-312
The aim of this study was to investigate the role of gender in histological and functional outcome, angiogenesis, neurogenesis and therapeutic effects of recombinant human erythropoietin (rhEPO) in mice after traumatic brain injury (TBI). TBI caused
Autor:
Asim Mahmood, Michael Chopp, Dunyue Lu, Chang Lu, Anton Goussev, Changsheng Qu, Zheng Gang Zhang
Publikováno v:
Journal of Neurosurgery. 107:392-397
Object This study was designed to investigate the neuroprotective properties of recombinant erythropoietin (EPO) and carbamylated erythropoietin (CEPO) administered following traumatic brain injury (TBI) in rats. Methods Sixty adult male Wistar rats
Autor:
Asim Mahmood, Jieli Chen, Chang Lu, Anton Goussev, Timothy J Schallert, Yi Li, Dunyue Lu, Changsheng Qu, Hao Jiang, Michael Chopp
Publikováno v:
Journal of Neurotrauma. 24:1132-1146
Traumatic brain injury (TBI) remains a major public health problem globally. Presently, there is no way to restore cognitive deficits caused by TBI. In this study, we seek to evaluate the effect of statins (simvastatin and atorvastatin) on the spatia
Publikováno v:
Neurosurgery. 60:546-554
Objective This study investigated the effects of a combination therapy of marrow stromal cells (MSCs) and statins (atorvastatin) after traumatic brain injury in rats. Methods Thirty-two female Wistar rats were injured by controlled cortical impact an
Publikováno v:
Journal of Neurosurgery. 104:272-277
Object This study was designed to follow the effects of bone marrow stromal cell (BMSC) administration in rats after traumatic brain injury (TBI) for a 3-month period. Methods Forty adult female Wistar rats were injured by a controlled cortical impac
Publikováno v:
Neurosurgery. 57:1026-1031
This study was designed to investigate the effects of human bone marrow stromal cell (hMSC) administration in rats for 3 months after traumatic brain injury (TBI).Adult male Wistar rats (n = 60) were injured with controlled cortical impact and divide
Publikováno v:
Journal of Neurosurgery. 103:695-701
Object. Atorvastatin administered after traumatic brain injury (TBI) induced by controlled cortical impact promotes functional improvement in male rats. Note, however, that parallel studies have not been performed in female rats. Therefore, the autho