Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Anton Golovnin"'
Autor:
Larisa Melnikova, Margarita Kostyuchenko, Alexander Parshikov, Pavel Georgiev, Anton Golovnin
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193497 (2018)
Su(Hw) belongs to the class of proteins that organize chromosome architecture and boundaries/insulators between regulatory domains. This protein contains a cluster of 12 zinc finger domains most of which are responsible for binding to three different
Externí odkaz:
https://doaj.org/article/0ad061441f3f48c984500e8c05567078
Autor:
Larisa Melnikova, Margarita Kostyuchenko, Varvara Molodina, Alexander Parshikov, Pavel Georgiev, Anton Golovnin
Publikováno v:
Open Biology, Vol 7, Iss 10 (2017)
The best-studied Drosophila insulator complex consists of two BTB-containing proteins, the Mod(mdg4)-67.2 isoform and CP190, which are recruited to the chromatin through interactions with the DNA-binding Su(Hw) protein. It was shown previously that M
Externí odkaz:
https://doaj.org/article/355a6e05c7484d93aff54327dae4578e
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140991 (2015)
Recent data suggest that insulators organize chromatin architecture in the nucleus. The best studied Drosophila insulator proteins, dCTCF (a homolog of the vertebrate insulator protein CTCF) and Su(Hw), are DNA-binding zinc finger proteins. Different
Externí odkaz:
https://doaj.org/article/ecea1a63ac9c4884b40d1336e642ff02
Publikováno v:
Doklady Biochemistry and Biophysics. 498:184-189
In Drosophila, the BEAF-32, Z4/putzig, and Chriz/Chromator proteins colocalize in the interbands of polytene chromosomes. It was assumed that these proteins can form a complex that affects the structure of chromatin. However, the mechanism of the for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4ccc5ab24d22b18a46511fb19e7a67e
https://doi.org/10.1134/s1607672921030066
https://doi.org/10.1134/s1607672921030066
Publikováno v:
Acta Naturae
The mechanisms underlying long-range interactions between chromatin regions and the principles of chromosomal architecture formation are currently under extensive scrutiny. A special class of regulatory elements known as insulators is believed to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0903f08d9184ce7e8959b3aca15fc7
https://doi.org/10.32607/actanaturae.11144
https://doi.org/10.32607/actanaturae.11144
Publikováno v:
Doklady Biochemistry and Biophysics. 486:175-180
It is found that, in embryonic D. melanogaster cells, Mod(mdg4) protein isoforms can interact with each other through BTB domains. However, this nonspecific interaction is destroyed as a result of recruitment of protein complexes to the chromatin sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0437c8e121b2ce80b95c55242e84a19
https://doi.org/10.1134/s1607672919030049
https://doi.org/10.1134/s1607672919030049
Publikováno v:
Vavilovskij Žurnal Genetiki i Selekcii, Vol 23, Iss 2, Pp 168-173 (2019)
The Su(Hw) protein was first identified as a DNA-binding component of an insulator complex in Drosophila. Insulators are regulatory elements that can block the enhancer-promoter communication and exhibit boundary activity. Some insulator complexes co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039b2438c790efd8a4f07291b0e701cc
https://doi.org/10.18699/vj19.477
https://doi.org/10.18699/vj19.477
Publikováno v:
Russian Journal of Genetics. 55:295-300
In D. melanogaster, the nuclear matrix protein EAST functionally interacts with the Su(Hw)-dependent insulator complex. The y2 allele, in which the MDG4 retrotransposon is inserted between enhancers and the gene promoter, was previously described. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6cb3053c5dd1a5443f7cae111e7487c
https://doi.org/10.1134/s1022795419030074
https://doi.org/10.1134/s1022795419030074
Autor:
Anton Golovnin, M. M. Erokhin, V. V. Molodina, D. A. Chetverina, P. V. Elizar’ev, M. V. Kostyuchenko, Larisa Melnikova, Pavel Georgiev
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Suppressor of Hairy-wing [Su(Hw)] is a DNA-binding architectural protein that participates in the organization of insulators and repression of promoters in Drosophila. This protein contains acidic regions at both ends and a central cluster of 12 zinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e758485bdd24e22c15c3b88dfcf3b6
http://link.springer.com/article/10.1038/s41598-019-41761-6
http://link.springer.com/article/10.1038/s41598-019-41761-6
Autor:
Marina Yu. Mazina, Anton Golovnin, Nadezhda E. Vorobyeva, Rustam H. Ziganshin, Mikhail D. Magnitov
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Proximity-dependent biotin labelling revealed undescribed participants of the ecdysone response in Drosophila. Two labelling enzymes (BioID2 and APEX2) were fused to EcR or Usp to biotin label the surrounding proteins. The EcR/Usp heterodimer was fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3488da274662b6c0ce9626a13b227586
http://europepmc.org/articles/PMC7075897
http://europepmc.org/articles/PMC7075897