Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Anton Beyer"'
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28778 (2011)
Pharmacological inhibition of cardiac hERG K(+) channels is associated with increased risk of lethal arrhythmias. Many drugs reduce hERG current by directly binding to the channel, thereby blocking ion conduction. Mutation of two aromatic residues (F
Externí odkaz:
https://doaj.org/article/bc466ea9fbd24dde873fbbe4f17382a0
Publikováno v:
Flavour and Fragrance Journal. 24:192-197
Studies on the odorant receptor cluster located on human chromosome 17, which contains 18 odorant receptor genes, are presented. After an extended search for orthologues of those odorant receptor genes in chimpanzee, rat and mouse genomes, comparison
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e75c143073345a4d2b2244fc05ccb52a
https://doi.org/10.1002/ffj.1933
https://doi.org/10.1002/ffj.1933
Publikováno v:
Current Computer Aided-Drug Design. 3:87-100
HIV-1 Reverse transcriptase (RT) is an essential enzyme for HIV-1 replication and, therefore, it is an important target for the attack of antiviral agents. Although some products are already on the market, there is need to design new drugs, because m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9ae14c38b0db61a2755b2f46d5ecd40
https://doi.org/10.2174/157340907780809507
https://doi.org/10.2174/157340907780809507
Autor:
Thomas Karl, Michael Löffler, Herbert Wimmer, Kamil Önder, Alena Pichová, Lore Koller, Anton Beyer, Albert Thür, Rimantas Kodzius, Torsten Klade, Michael Breitenbach, Harald Hundsberger
Publikováno v:
Current Genetics. 34:419-429
The yeast gene, GRC5 (growth control), is a member of the highly conserved QM gene family, the human member of which has been associated with the suppression of Wilms' tumor. GRC5 encodes ribosomal protein L10, which is thought to play a regulatory r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff948f722f0c8703da2fb987355bf9f
https://doi.org/10.1007/s002940050416
https://doi.org/10.1007/s002940050416
Autor:
Supa Hannongbua, Patchreenart Saparpakorn, Auradee Punkvang, Peter Wolschann, Anton Beyer, Pornpan Pungpo
Publikováno v:
European journal of medicinal chemistry. 45(12)
Arylamides have been identified as direct InhA inhibitors which overcome the drug-resistance problem of isoniazid, the first-line drug for tuberculosis treatment. However, arylamide properties are not yet optimal against Mycobacterium tuberculosis .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4544a2481b8527043490ea1fdf7f40c0
https://pubmed.ncbi.nlm.nih.gov/20888672
https://pubmed.ncbi.nlm.nih.gov/20888672
Publikováno v:
Monatshefte f�r Chemie Chemical Monthly. 123:417-423
Summary. The conformation of garuganin-I was analyzed in terms of the mobility of the cyclic structure. Molecular mechanics calculations were applied to show that the interconversion of the optical isomers is not possible at room temperature due to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d6edcebf5526a8252032e2b443c6bc5
https://doi.org/10.1007/bf00817597
https://doi.org/10.1007/bf00817597
Autor:
Anton Beyer, Peter Schuster
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 121:339-349
The international motions of a single cyclohexane molecule are studied by molecular dynamics calculations. Classical trajectories are calculated by integrating Newton's equation of motion. The potential functions used are essentially the same as in A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4fda8d70ef0276e53cae45527feb09d
https://doi.org/10.1007/bf00809448
https://doi.org/10.1007/bf00809448
Publikováno v:
Scopus-Elsevier
The conformations of the HIV-1 reverse transcriptase inhibitor 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) are calculated by semiempirical and mainly by ab initio methods in order to estimate the potential for the rotation around the car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996334d93a3f7ce31bebad481ed3ae69
https://pubmed.ncbi.nlm.nih.gov/10195434
https://pubmed.ncbi.nlm.nih.gov/10195434
Autor:
Anton Beyer, Aron Bauer
Publikováno v:
Scopus-Elsevier
We present a novel method to improve a simple pair potential of mean force, derived from experimentally determined protein structures, in such a way that it recognizes native protein folds with high reliability. This improvement is based on the use o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f1b653be9748d68ae185cac853ab6a
https://pubmed.ncbi.nlm.nih.gov/8202466
https://pubmed.ncbi.nlm.nih.gov/8202466
Publikováno v:
Monatshefte fuer Chemie/Chemical Monthly. 130:1347
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96db0a54f89f250c9598914f918865ed
https://doi.org/10.1007/s007060050293
https://doi.org/10.1007/s007060050293